Abstract: Disclosed is a disposable diaper that has one or more chemical reagents provided in the absorbent region of the diaper, which comes into contact with urine when a patient wearing the diaper urinates. These chemical reagents change color when they contact urine containing abnormal levels of substances, such as leukocytes, blood, glucose, nitrites, protein, ketones, bilirubin, or urobilinogen; which substances may indicate the presence of a medical abnormality. Such a color change provides a visible indication of an abnormality in the urine and thus a possible incipient medical condition, such as a urinary tract infection, diabetes mellitus, hematuria, or the like. Such a color change is easily assessed by personnel having limited medical training, allowing such personnel to screen patients for these medical conditions and refer them to the appropriate medical personnel.