Abstract: Systems and methods are provided including a universal connector hub that may be removably coupled to a return cannula for fluid communication with a patient's vasculature for permitting a user to select between directing blood flow through a first portion of the connector hub in a cannula mode and enabling an interventional medical procedure through a second large bore portion of the connector hub in a sheath mode, or performing both the cannula and sheath modes simultaneously. The connector hub may comprise first and second Luer ports for auto-washout stasis regions of blood and/or for redirecting blood for perfusion of the patient's distal extremities. The systems may include a series of accessory components, such as removable caps for temporarily sealing respective portions of the connector hub, providing a hemostatic valve, and/or coupling to additional accessory components to provide further operational versatility and functionality.

Abstract: Systems are provided including a sheath and cannula combination device for permitting a user to select between directing blood flow through a first cannula portion of the combination device in a cannula mode and enabling an interventional medical procedure through a second sheath portion of the combination device in a sheath mode, or performing both the cannula mode and the sheath mode simultaneously. The combination device may include a connector hub configured to auto-washout stasis regions of blood within the first cannula portion. The systems may include a series of removable caps for temporarily sealing the first cannula portion and/or the second sheath portion of the combination device, such that the user may seamlessly select when to use the combination device in the cannula mode, the sheath mode, both the cannula mode and the sheath mode simultaneously, or neither the cannula mode nor the sheath mode.

Abstract: Disclosed is a blood oxygenator for a premature fetus comprising a housing defining a cavity therein, wherein the housing comprises a blood inlet, a blood outlet, a gas inlet, and a gas outlet; and a gas exchanger disposed within the cavity, wherein the gas exchanger comprises a plurality of hollow fibers arranged in a pattern allowing blood to flow past the hollow fibers when in contact with the hollow fibers, wherein the hollow fibers comprise a receiving end in communication with the gas inlet for receiving a sweep gas and an emitting end in communication with the gas outlet from which the sweep gas exits, wherein the oxygenator is designed to rely on the fetal heart as sole blood pump.

Abstract: Systems are provided including a sheath and cannula combination device for permitting a user to select between directing blood flow through a first cannula portion of the combination device in a cannula mode and enabling an interventional medical procedure through a second sheath portion of the combination device in a sheath mode, or performing both modes simultaneously. The combination device may include a connector hub configured to auto-washout stasis regions of blood within the first cannula portion. The system may include a series of removable caps for temporarily sealing the first and/or second portions of the combination device, such that the user may seamlessly select when to use the combination device in the cannula mode, the sheath mode, both the cannula and sheath modes simultaneously, or neither the cannula mode nor the sheath mode.

Abstract: A blood oxygenator includes a housing having a first end opposite a second end with a sidewall extending between the first end and the second end along a longitudinal axis. The housing defines an interior chamber having a liquid inlet at the first end and a liquid outlet at the second end. The oxygenator further includes a gas exchange assembly positioned within the interior chamber. The gas exchange assembly includes a retainer having an upper cap spaced apart from a lower cap by one or more spacers, and a gas exchange medium disposed between the upper cap and the lower cap. The gas exchange medium has a plurality of subunits stacked on top of each other, with each subunit having a plurality of layers of hollow fiber mats.

Abstract: A blood oxygenator includes a housing having a first end opposite a second end with a sidewall extending between the first end and the second end along a longitudinal axis. The housing defines an interior chamber having a liquid inlet at the first end and a liquid outlet at the second end. The oxygenator further includes a gas exchange assembly positioned within the interior chamber. The gas exchange assembly includes a retainer having an upper cap spaced apart from a lower cap by one or more spacers, and a gas exchange medium disposed between the upper cap and the lower cap. The gas exchange medium has a plurality of subunits stacked on top of each other, with each subunit having a plurality of layers of hollow fiber mats.

Abstract: A blood oxygenator has a housing with a first end opposite a second end and a sidewall extending between the first end and the second end along a longitudinal axis. The housing may define an interior chamber having a fluid inlet and a fluid outlet. The blood oxygenator further has a gas exchange medium positioned within the interior chamber. The gas exchange medium may have a plurality of hollow fibers rolled into a spiral shape. The blood oxygenator further has a flow diverter positioned within the interior chamber and configured for guiding fluid flow through the gas exchange medium.

Abstract: A blood oxygenator includes a housing having a blood inlet, a blood outlet, a gas inlet, and a gas outlet; and a gas exchange medium having a plurality of hollow fibers in fluid communication with the gas inlet and the gas outlet. Each of the hollow fibers has a roughened outer surface configured to decrease a thickness of a boundary layer at an interface between blood and the roughened outer surface and increase a gas exchange rate at the interface.

Abstract: A blood oxygenator includes a housing having a first end opposite a second end with a sidewall extending between the first end and the second end along a longitudinal axis. The housing defines an interior chamber having a liquid inlet at the first end and a liquid outlet at the second end. The oxygenator further includes a gas exchange assembly positioned within the interior chamber. The gas exchange assembly includes a retainer having an upper cap spaced apart from a lower cap by one or more spacers, and a gas exchange medium disposed between the upper cap and the lower cap. The gas exchange medium has a plurality of subunits stacked on top of each other, with each subunit having a plurality of layers of hollow fiber mats.

Abstract: A winged securement device includes a flexible base having an adhesive side and an opposite non-adhesive side. A generally planar, integral elastomeric anchoring member is mounted on the base non-adhesive side. The anchoring member includes a pair of opposing gripping tabs formed therein the anchoring member and a slit disposed between the tabs. The gripping tabs may be pulled to open the slit for receiving wings of a catheter hub therein and for securing the wings between the anchoring member and the base.