Patents by Inventor William GO

William GO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240082307
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes methods of identifying a patient who would respond well to a T cell therapy or conditioning a patient prior to a T cell therapy so that the patient responds well to a T cell therapy. The conditioning involves administering one or more preconditioning agents prior to a T cell therapy and identifying biomarker cytokines prior to administering a T cell therapy.
    Type: Application
    Filed: August 24, 2023
    Publication date: March 14, 2024
    Applicants: Kite Pharma, Inc., Ofc of Tech Transfer, NIH
    Inventors: Adrian BOT, Jeffrey S. WIEZOREK, William GO, Rajul JAIN, James N. KOCHENDERFER, Steven A. ROSENBERG
  • Patent number: 11779601
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes methods of identifying a patient who would respond well to a T cell therapy or conditioning a patient prior to a T cell therapy so that the patient responds well to a T cell therapy. The conditioning involves administering one or more preconditioning agents prior to a T cell therapy and identifying biomarker cytokines prior to administering a T cell therapy.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: October 10, 2023
    Assignees: Kite Pharma, Inc., The United States of America as represented by the Secretary, Department of Health and Human Services
    Inventors: Adrian Bot, Jeffrey S. Wiezorek, William Go, Rajul Jain, James N. Kochenderfer, Steven A. Rosenberg
  • Publication number: 20230158075
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a patient prior to a T cell therapy, wherein the conditioning involves administering a combination of cyclophosphamide and fludarabine.
    Type: Application
    Filed: September 27, 2022
    Publication date: May 25, 2023
    Applicants: Kite Pharma Inc., United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Adrian BOT, Jeffrey WIEZOREK, William GO, Rajul JAIN, James N. KOCHENDERFER, Steven A. ROSENBERG
  • Patent number: 11491187
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a patient prior to a T cell therapy, wherein the conditioning involves administering a combination of cyclophosphamide and fludarabine.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: November 8, 2022
    Assignees: Kite Pharma, Inc., The United States of America as Represented by the Secretary, Department of Health and Human Services
    Inventors: Adrian Bot, Jeffrey S. Wiezorek, William Go, Rajul Jain, James N. Kochenderfer, Steven A. Rosenberg
  • Publication number: 20220169694
    Abstract: The disclosure provides methods of treating a malignancy comprising administering an effective dose of a chimeric antigen receptor genetically modified T cell immunotherapy and methods for manufacturing such immunotherapy. Some aspects of the disclosure relate to methods of determining objective response of a patient to a T cell immunotherapy based on the levels of attributes prior to and after administration of the immunotherapy to the patient.
    Type: Application
    Filed: February 20, 2021
    Publication date: June 2, 2022
    Inventors: Adrian Bot, John Rossi, Vicki Plaks, Szu-Ting Chou, William Go, Jenny Jiyun Kim
  • Patent number: 10322146
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a patient prior to a T cell therapy, wherein the conditioning involves administering a combination of cyclophosphamide and fludarabine.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: June 18, 2019
    Assignees: Kite Pharma, Inc., The United States of America as Represented by the Secretary, Department of Health and Human Services
    Inventors: Adrian Bot, Jeffrey S. Wiezorek, William Go, Rajul Jain, James N. Kochenderfer, Steven A. Rosenberg
  • Publication number: 20180369283
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a patient prior to a T cell therapy, wherein the conditioning involves administering a combination of cyclophosphamide and fludarabine.
    Type: Application
    Filed: April 10, 2018
    Publication date: December 27, 2018
    Applicants: Kite Pharma, Inc., United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Adrian BOT, Jeffrey S. WIEZOREK, William GO, Rajul JAIN, James N. KOCHENDERFER, Steven A. ROSENBERG
  • Publication number: 20180344767
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes methods of identifying a patient who would respond well to a T cell therapy or conditioning a patient prior to a T cell therapy so that the patient responds well to a T cell therapy. The conditioning involves administering one or more preconditioning agents prior to a T cell therapy and identifying biomarker cytokines prior to administering a T cell therapy.
    Type: Application
    Filed: May 27, 2016
    Publication date: December 6, 2018
    Applicants: Kite Pharma, Inc., The United States of America as represented by the Secretary Department of Health and Human Services
    Inventors: Adrian BOT, Jeffrey S. WIEZOREK, William GO, Rajul JAIN, James N. KOCHENDERFER, Steven A. ROSENBERG
  • Patent number: 9855298
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a patient prior to a T cell therapy, wherein the conditioning involves administering a combination of cyclophosphamide and fludarabine.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: January 2, 2018
    Assignees: Kite Pharma, Inc., The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: Adrian Bot, Jeffrey S. Wiezorek, William Go, Rajul Jain, James N. Kochenderfer, Steven A. Rosenberg
  • Publication number: 20170368101
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a patient prior to a T cell therapy, wherein the conditioning involves administering a combination of cyclophosphamide and fludarabine.
    Type: Application
    Filed: July 13, 2017
    Publication date: December 28, 2017
    Applicants: Kite Pharma, Inc., United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Adrian BOT, Jeffrey S. WIEZOREK, William GO, Rajul JAIN, James N. KOCHENDERFER, Steven A. ROSENBERG
  • Publication number: 20160346326
    Abstract: The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a patient prior to a T cell therapy, wherein the conditioning involves administering a combination of cyclophosphamide and fludarabine.
    Type: Application
    Filed: May 27, 2016
    Publication date: December 1, 2016
    Applicants: Kite Pharma, Inc., National Cancer Institute
    Inventors: Adrian BOT, Jeffrey S. WIEZOREK, William GO, Rajul JAIN, James N. KOCHENDERFER, Steven A. ROSENBERG
  • Patent number: 8161067
    Abstract: A method and apparatus for managing complex presentation objects using globally-unique identifiers. Downloaded objects are identified by globally-unique identifiers to maintain object integrity and to facilitate capturing downloaded objects for reuse without additional download time overhead. An object may be referenced by selected indicia, such as a name, a globally-unique identifier or a globally-unique identifier and an object locator, The object is located by the selected indicia. Then, a decision is made whether to allow capture of the object based upon whether the selected indicia includes a globally-unique identifier and is secure.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: April 17, 2012
    Assignee: International Business Machines Corporation
    Inventors: Reinhard Heinrich Hohensee, Craig D Brossman, Robert William Goings, Arthur Ray Roberts, John Thomas Varga, Calvin Larry Doescher, Lynn Mette Mastie, David Earl Stone, Dwight Ross Palmer
  • Patent number: 7265854
    Abstract: A method and apparatus for managing complex presentation objects using globally-unique identifiers. Downloaded objects are identified by globally-unique identifiers to maintain object integrity and to facilitate capturing downloaded objects for reuse without additional download time overhead. An object may be referenced by selected indicia, such as a name, a globally-unique identifier or a globally-unique identifier and an object locator, The object is located by the selected indicia. Then, a decision is made whether to allow capture of the object based upon whether the selected indicia includes a globally-unique identifier and is secure.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: September 4, 2007
    Assignee: International Business Machines Corporation
    Inventors: Reinhard Heinrich Hohensee, Craig D Brossman, Robert William Goings, Arthur Ray Roberts, John Thomas Varga, Calvin Larry Doescher, Lynn Mette Mastie, David Earl Stone, Dwight Ross Palmer
  • Publication number: 20040156075
    Abstract: A method and apparatus for managing complex presentation objects using globally-unique identifiers. Downloaded objects are identified by globally-unique identifiers to maintain object integrity and to facilitate capturing downloaded objects for reuse without additional download time overhead. An object may be referenced by selected indicia, such as a name, a globally-unique identifier or a globally-unique identifier and an object locator, The object is located by the selected indicia. Then, a decision is made whether to allow capture of the object based upon whether the selected indicia includes a globally-unique identifier and is secure.
    Type: Application
    Filed: February 3, 2004
    Publication date: August 12, 2004
    Applicant: International Business Machines Corporation
    Inventors: Reinhard Heinrich Hohensee, Craig D. Brossman, Robert William Goings, Arthur Ray Roberts, John Thomas Varga, Calvin Larry Doescher, Lynn Mette Mastie, David Earl Stone, Dwight Ross Palmer