Abstract: Techniques disclosed herein relate to inferring a type of multiple sclerosis and determining whether to output an alert based on codes detected within noisy assessment data corresponding to a subject. The noisy assessment data includes content originating from a care provider that identifies a characteristic of the subject or of a treatment for the subject, and the subject has been diagnosed with multiple sclerosis. A temporal dynamic or distribution is determined based on instances of the code detection, and a modulation is determined based on the temporal dynamic or the distribution. It is determined whether an alert criterion is satisfied based on whether the modulation is above a threshold so as to represent noise or a predicted transition across types of multiple sclerosis. The inferred type of multiple sclerosis is output. When the alert criterion is satisfied, an alert is output as well.

Abstract: Provided are processes that include: obtaining, with a computer system, a time-series machine learning model trained to influence the actions of an agent; selecting, with the computer system, with the time-series machine learning model, stimuli to drive the agent to engage in a targeted activity; causing, with the computer system, the stimuli to be presented to the agent; obtaining, with the computer system, feedback indicative of whether the agent engaged in the targeted activity; adjusting, with the computer system, parameters of the time-series machine learning based on the feedback; and storing, with the computer system, the adjusted parameters in memory.

Abstract: A method for treating a patient suffering from allergy by desensitizing the patient to an allergen component that includes orally, sublingually, or intranasally administering to the patient a therapeutically effective amount of an immunomodulating composition and successively repeating the administration at a selected interval with the therapeutically effective amount of each successive administration comprising an increasing amount of the allergen component. The composition includes an amount of the allergen component that is sufficient to impart an immune response and a pharmaceutically acceptable carrier that is at least substantially free of phenol. The successive repeating occurs a sufficient number of times to reduce patient sensitivity to the allergen component, and avoids or minimizes oral adverse effects. An immunomodulating product is also described.

Abstract: A company's ability to expand its market presence by delivering value to emerging and immature markets is influenced by its ability to develop a rich and differentiated value net within these emerging markets. Techniques are disclosed for making resource placement decisions in an objective manner, using results from a value chain analysis. Geographies or locations that are candidates for the resource placement are analyzed in terms of a set of criteria which, in preferred embodiments, are directed toward identifying strengths and weaknesses of each location as part of an overall value chain.