Patents by Inventor William Griffiths
William Griffiths has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240131268Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.Type: ApplicationFiled: November 27, 2023Publication date: April 25, 2024Inventors: Arthur Uber, III, Chelsea Marsh, William Barone, Michael McDermott, Timothy Newing, Michael Spohn, Vince Delbrugge, Ralph Schriver, Kevin Cowan, David Griffiths
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Publication number: 20240108844Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.Type: ApplicationFiled: September 20, 2023Publication date: April 4, 2024Inventors: Hamish Adrian OSBORNE, Gavin Walsh Millar, Stephen David Evans, Bruce Gordon Holyoake, James William Stanton, David Leon McCauley, Gareth Thomas McDermott, Nicholas James Michael McKenna, Myfanwy Jane Antica Norton, Adrian John Elsworth, Michael John Andresen, Jonathan Andrew George Lambert, Sandeep Singh Gurm, Tessa Hazel Paris, Joseph Nathaniel Griffiths, Ping Si, Christopher Gareth Sims, Elmo Benson Stoks, Dexter Chi Lun Cheung, Peter Alan Seekup, Po-Yen Liu, Richard Edward Lang, Paul James Tonkin, Ian Lee Wai Kwan
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Patent number: 11947600Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and wired and wireless network communications to interface among repositories of disparate datasets and computing machine-based entities configured to access datasets, and, more specifically, to a computing and data storage platform to implement computerized tools to facilitate expedited queries based on query results generated by disparate computing and database architectures, according to at least some examples. For example, a method may include generating multiple results of queries, storing the multiple results of queries in a memory, and linking each of the multiple results of queries to a portion of data stored in a graph. The method can include receiving data representing a query and accessing data representing quiescent data values to form a query result.Type: GrantFiled: November 30, 2021Date of Patent: April 2, 2024Assignee: data.world, Inc.Inventors: David Lee Griffith, Shad William Reynolds
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Patent number: 11941140Abstract: Various techniques are described for platform management of integrated access of public and privately-accessible datasets utilizing federated query generation and query schema rewriting optimization, including receiving at a dataset access platform a query formatted according to a first data schema, generating a copy of the query, saving the query and the copy to a datastore, parsing the copy of the query in the first schema using an inference engine, determining whether the query comprises data associated with an access control condition associated with accessing the dataset, the access control condition being configured to indicate whether the query is permitted to access the dataset, and rewriting, using a proxy server, the copy of the query in a second schema, and optimizing the rewriting by identifying a database engine to execute the query and including other data converted into another triple associated with an attribute of the query.Type: GrantFiled: June 30, 2022Date of Patent: March 26, 2024Assignee: data.world, Inc.Inventors: Bryon Kristen Jacob, David Lee Griffith, Triet Minh Le, Shad William Reynolds, Arthur Albert Keen
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Patent number: 11939321Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.Type: GrantFiled: April 7, 2021Date of Patent: March 26, 2024Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Valerio Berdini, Ildiko Maria Buck, James Edward Harvey Day, Charlotte Mary Griffiths-Jones, Thomas Daniel Heightman, Steven Howard, Christopher William Murray, David Norton, Marc O'Reilly, Alison Jo-Anne Woolford, Michael Liam Cooke, David Cousin, Stuart Thomas Onions, Jonathan Martin Shannon, John Paul Watts
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Patent number: 11925202Abstract: A smoking article may include a cigarette incorporated within an electrically powered aerosol generating device that acts as a holder for that cigarette. The smoking article possesses at least one form of tobacco. The smoking article also possesses a mouth-end piece that is used by the smoker to inhale components of tobacco that are generated by the action of heat upon components of the cigarette. A representative smoking article possesses an outer housing incorporating a source of electrical power (e.g., a battery), a sensing mechanism for powering the device at least during periods of draw, and a heating device (e.g., at least one electrical resistance heating element) for forming a thermally generated aerosol that incorporates components of tobacco. During use, the cigarette is positioned within the device, and after use, the used cigarette is removed from the device and replaced with another cigarette.Type: GrantFiled: March 31, 2023Date of Patent: March 12, 2024Assignee: RAI Strategic Holdings, Inc.Inventors: John Howard Robinson, David William Griffith, Jr., Billy Tyrone Conner, Evon Llewellyn Crooks, Dempsey Bailey Brewer, Jr.
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Patent number: 11928596Abstract: Various techniques are described for platform management of integrated access of public and privately-accessible datasets utilizing federated query generation and query schema rewriting optimization, including receiving at a dataset access platform a query formatted according to a first data schema, generating a copy of the query, saving the query and the copy to a datastore, parsing the copy of the query in the first schema using an inference engine, determining whether the query comprises data associated with an access control condition associated with accessing the dataset, the access control condition being configured to indicate whether the query is permitted to access the dataset, and rewriting, using a proxy server, the copy of the query in a second schema by converting the copy of the query into a triple associated with the query and another triple associated with the access control condition.Type: GrantFiled: May 31, 2022Date of Patent: March 12, 2024Assignee: data.world, Inc.Inventors: Bryon Kristen Jacob, David Lee Griffith, Triet Minh Le, Shad William Reynolds, Arthur Albert Keen
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Publication number: 20240000129Abstract: A smoking article may include a cigarette incorporated within an electrically powered aerosol generating device that acts as a holder for that cigarette. The smoking article possesses at least one form of tobacco. The smoking article also possesses a mouth-end piece that is used by the smoker to inhale components of tobacco that are generated by the action of heat upon components of the cigarette. A representative smoking article possesses an outer housing incorporating a source of electrical power (e.g., a battery), a sensing mechanism for powering the device at least during periods of draw, and a heating device (e.g., at least one electrical resistance heating element) for forming a thermally generated aerosol that incorporates components of tobacco. During use, the cigarette is positioned within the device, and after use, the used cigarette is removed from the device and replaced with another cigarette.Type: ApplicationFiled: September 18, 2023Publication date: January 4, 2024Inventors: John Howard Robinson, David William Griffith, Jr., Billy Tyrone Conner, Evon Llewellyn Crooks, Dempsey Bailey Brewer, Jr.
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Publication number: 20230416299Abstract: Pharmaceutical compositions comprising cholestenoic acids and deuterated derivatives thereof, methods of treatment or prevention of neurodegenerative conditions, as well as diagnostic methods and novel biomarkers form aspects of the invention.Type: ApplicationFiled: January 20, 2023Publication date: December 28, 2023Inventors: William Griffiths, Yuqin Wang, Spyridon Theofilopoulos, John Normanton, Ernest Arenas
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Patent number: 11827405Abstract: An apparatus for removing goods from a two-part carton having a base and a lid, the base being formed with side walls having external gussets secured against external side faces of the carton, the apparatus including: a lid removal module for engaging the lid and removing it from the carton; expansion members configured to be advanced between the gussets and the external side faces of the carton to remove the gussets from the side faces; engagement members for engaging side walls of the base and drawing them away from the goods and holding them in a position away from the goods; and a goods transfer module for engaging the goods and removing them from the carton.Type: GrantFiled: August 7, 2020Date of Patent: November 28, 2023Assignee: VISY R & D PTY LTDInventors: Michael William Griffith, Kaine Michael Cole, Derek Ian Campbell Ford, Matthew Stevens
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Patent number: 11805806Abstract: A smoking article may include a cigarette incorporated within an electrically powered aerosol generating device that acts as a holder for that cigarette. The smoking article possesses at least one form of tobacco. The smoking article also possesses a mouth-end piece that is used by the smoker to inhale components of tobacco that are generated by the action of heat upon components of the cigarette. A representative smoking article possesses an outer housing incorporating a source of electrical power (e.g., a battery), a sensing mechanism for powering the device at least during periods of draw, and a heating device (e.g., at least one electrical resistance heating element) for forming a thermally generated aerosol that incorporates components of tobacco. During use, the cigarette is positioned within the device, and after use, the used cigarette is removed from the device and replaced with another cigarette.Type: GrantFiled: February 8, 2019Date of Patent: November 7, 2023Assignee: RAI Strategic Holdings, Inc.Inventors: John Howard Robinson, David William Griffith, Jr., Billy Tyrone Conner, Evon Llewellyn Crooks, Dempsey Bailey Brewer, Jr.
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Patent number: 11785978Abstract: A smoking article may include a cigarette incorporated within an electrically powered aerosol generating device that acts as a holder for that cigarette. The smoking article possesses at least one form of tobacco. The smoking article also possesses a mouth-end piece that is used by the smoker to inhale components of tobacco that are generated by the action of heat upon components of the cigarette. A representative smoking article possesses an outer housing incorporating a source of electrical power (e.g., a battery), a sensing mechanism for powering the device at least during periods of draw, and a heating device (e.g., at least one electrical resistance heating element) for forming a thermally generated aerosol that incorporates components of tobacco. During use, the cigarette is positioned within the device, and after use, the used cigarette is removed from the device and replaced with another cigarette.Type: GrantFiled: February 8, 2019Date of Patent: October 17, 2023Assignee: RAI Strategic Holdings, Inc.Inventors: John Howard Robinson, David William Griffith, Jr., Billy Tyrone Conner, Evon Llewellyn Crooks, Dempsey Bailey Brewer, Jr.
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Patent number: 11758936Abstract: A smoking article may include a cigarette incorporated within an electrically powered aerosol generating device that acts as a holder for that cigarette. The smoking article possesses at least one form of tobacco. The smoking article also possesses a mouth-end piece that is used by the smoker to inhale components of tobacco that are generated by the action of heat upon components of the cigarette. A representative smoking article possesses an outer housing incorporating a source of electrical power (e.g., a battery), a sensing mechanism for powering the device at least during periods of draw, and a heating device (e.g., at least one electrical resistance heating element) for forming a thermally generated aerosol that incorporates components of tobacco. During use, the cigarette is positioned within the device, and after use, the used cigarette is removed from the device and replaced with another cigarette.Type: GrantFiled: February 16, 2022Date of Patent: September 19, 2023Assignee: RAI Strategic Holdings, Inc.Inventors: John Howard Robinson, David William Griffith, Jr., Billy Tyrone Conner, Evon Llewellyn Crooks, Dempsey Bailey Brewer, Jr.
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Publication number: 20230232886Abstract: A smoking article may include a cigarette incorporated within an electrically powered aerosol generating device that acts as a holder for that cigarette. The smoking article possesses at least one form of tobacco. The smoking article also possesses a mouth-end piece that is used by the smoker to inhale components of tobacco that are generated by the action of heat upon components of the cigarette. A representative smoking article possesses an outer housing incorporating a source of electrical power (e.g., a battery), a sensing mechanism for powering the device at least during periods of draw, and a heating device (e.g., at least one electrical resistance heating element) for forming a thermally generated aerosol that incorporates components of tobacco. During use, the cigarette is positioned within the device, and after use, the used cigarette is removed from the device and replaced with another cigarette.Type: ApplicationFiled: March 31, 2023Publication date: July 27, 2023Inventors: John Howard Robinson, David William Griffith, Jr., Billy Tyrone Conner, Evon Llewellyn Crooks, Dempsey Bailey Brewer, Jr.
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Publication number: 20230175016Abstract: The present invention provides a viral vector comprising a nucleotide sequence encoding a complement protein, wherein the nucleotide sequence is operably linked to a podocyte-specific promoter and/or the viral vector is capable of specifically transducing podocytes.Type: ApplicationFiled: June 30, 2021Publication date: June 8, 2023Inventors: Alan William Griffith, Lukas Stanczuk, Valeryia Kuzmuk, Chris Hollowood, Dominic Schmidt, Moin Ahson Saleem-Uddin, Gavin Iain Welsh
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Patent number: 11647781Abstract: A smoking article may include a cigarette incorporated within an electrically powered aerosol generating device that acts as a holder for that cigarette. The smoking article possesses at least one form of tobacco. The smoking article also possesses a mouth-end piece that is used by the smoker to inhale components of tobacco that are generated by the action of heat upon components of the cigarette. A representative smoking article possesses an outer housing incorporating a source of electrical power (e.g., a battery), a sensing mechanism for powering the device at least during periods of draw, and a heating device (e.g., at least one electrical resistance heating element) for forming a thermally generated aerosol that incorporates components of tobacco. During use, the cigarette is positioned within the device, and after use, the used cigarette is removed from the device and replaced with another cigarette.Type: GrantFiled: May 9, 2022Date of Patent: May 16, 2023Assignee: RAI Strategic Holdings, Inc.Inventors: John Howard Robinson, David William Griffith, Jr., Billy Tyrone Conner, Evon Llewellyn Crooks, Dempsey Bailey Brewer, Jr.
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Patent number: 11641871Abstract: A smoking article may include a cigarette incorporated within an electrically powered aerosol generating device that acts as a holder for that cigarette. The smoking article possesses at least one form of tobacco. The smoking article also possesses a mouth-end piece that is used by the smoker to inhale components of tobacco that are generated by the action of heat upon components of the cigarette. A representative smoking article possesses an outer housing incorporating a source of electrical power (e.g., a battery), a sensing mechanism for powering the device at least during periods of draw, and a heating device (e.g., at least one electrical resistance heating element) for forming a thermally generated aerosol that incorporates components of tobacco. During use, the cigarette is positioned within the device, and after use, the used cigarette is removed from the device and replaced with another cigarette.Type: GrantFiled: January 14, 2019Date of Patent: May 9, 2023Assignee: RAI Strategic Holdings, Inc.Inventors: John Howard Robinson, David William Griffith, Jr., Billy Tyrone Conner, Evon Llewellyn Crooks, Dempsey Bailey Brewer, Jr.
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Publication number: 20230132848Abstract: A casing for a fragmentation weapon has a fragmentation layer 1 of preformed fragments 3 slidably fitted within preformed cells 6 of a lattice 2 sandwiched between an inner casing layer 4 and outer casing layer 5. The casing is particularly suited to use in fragmentation weapons and warheads. Upon detonation of the weapon, the preformed fragments 3 can freely separate from their cells 6 without being attached to the lattice 2 or other fragments 3.Type: ApplicationFiled: February 17, 2021Publication date: May 4, 2023Inventor: Owain Stephen William Griffiths
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Publication number: 20230077424Abstract: An example computer-implemented method of controlling access to a storage system includes using, in response to a request to access a resource of the storage system during a transitional state associated with a transition of the storage system to use a security protocol to control access to the storage system, a guest role to control access to the resource of the storage system when the request does not include a token identifierType: ApplicationFiled: November 18, 2022Publication date: March 16, 2023Inventors: Luis Pablo Pabón, Grant William Griffiths
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Patent number: 11602175Abstract: The present invention provides a conductive substrate useful for Joule heating, such as in an electronic smoking article. Particularly, the invention provides a resistive heating element formed of a conductive substrate. The conductive substrate comprises an electrically conductive material and a carbonaceous additive, such as a binder material. The conductive substrate is carbonized in that it is subjected to calcining conditions to effectively reduce the carbonaceous additive to its carbon skeleton. It has been found that such carbonized substrate has surprisingly improved resistance properties in relation a substrate of the same formulation that is not carbonized. The carbonized substrate can include an aerosol precursor material. The formed resistive heating element can be included in an electronic smoking article to simultaneously provide resistive heating and aerosol formation with a single, unitary component.Type: GrantFiled: May 4, 2020Date of Patent: March 14, 2023Assignee: RAI Strategic Holdings, Inc.Inventors: David William Griffith, Jr., Yi-Ping Chang, Calvin W. Henderson, Ricky Lee Montgomery, Walter Charles Liebscher, II, Chandra Kumar Banerjee, Paul E. Braxton, Stephen Benson Sears, Kenneth Allen Beard, Timothy Brian Nestor, Balager Ademe, Frederic Philippe Ampolini, Dennis Lee Potter