Abstract: Reversibly inhibited antibodies are disclosed, suitable for treatment of diseases such as cancer. The reversibly inhibited antibodies are such that they regain their activity on illumination, for example with UV light. Compositions containing such antibodies, methods of preparation of such antibodies and methods of use of such antibodies are also disclosed. The moiety employed to provide reversible inhibition may comprise a hydrophilic polymer such as polyethylene glycol.

Abstract: Anti-inflammatory compositions are prepared which comprise a therapeutically effective amount of a compound of the formula ##STR1## wherein X is CO or CHOH; Y is CO, an oxygen atom or a direct bond; the dotted line represents a double bond which is optionally present when Y is an oxygen atom or a direct bond; R.sub.1 is hydrogen or methyl; R.sub.2 is hydrogen, fluorine, chlorine, bromine, methyl, trifluoromethyl, methoxyl, hydroxyl, acetoxyl, nitro or amino; R.sub.3 is alkyl of 3-8 carbon atoms, cycloalkyl of 3-8 carbon atoms, alkenyl of 3-8 carbon atoms, cycloalkenyl of 5-8 carbon atoms, phenyl or phenyl substituted by 1 or 2 substituents selected from the group consisting of fluorine, chlorine, bromine, methyl, ethyl, methoxyl, ethoxyl, benzyloxyl, hydroxyl, acetoxyl, trifluoromethyl, nitro, amino, acetyl, methylthiol, methylsulphonyl, methylamino and dimethylamino.Compounds of the above formula are novel except that R.sub.1 must be methyl: when R.sub.3 -- Y is a 4-phenyl group, R.sub.