Patents by Inventor William H. Bothfeld

William H. Bothfeld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified bacteria for enhanced bioproduction and methods of using the same
    Patent number: 12168679
    Abstract: The present disclosure relates generally to modified bacteria, such as E. coli, with modification in the expression of at least one gene encoding a type I and/or type II toxin-antitoxin (TA) system protein and/or at least one gene encoding a structural protein that modulates ribosomes and methods of using the disclosed bacteria for producing a biological compound of interest. The modifications of the bacteria result in enhanced bioproduction.
    Type: Grant
    Filed: November 9, 2021
    Date of Patent: December 17, 2024
    Assignee: Northwestern University
    Inventors: William H. Bothfeld, Keith E. J. Tyo
  • MODIFIED BACTERIA FOR ENHANCED BIOPRODUCTION AND METHODS OF USING THE SAME
    Publication number: 20220144899
    Abstract: The present disclosure relates generally to modified bacteria, such as E. coli, with modification in the expression of at least one gene encoding a type I and/or type II toxin-antitoxin (TA) system protein and/or at least one gene encoding a structural protein that modulates ribosomes and methods of using the disclosed bacteria for producing a biological compound of interest. The modifications of the bacteria result in enhanced bioproduction.
    Type: Application
    Filed: November 9, 2021
    Publication date: May 12, 2022
    Applicant: Northwestern University
    Inventors: William H. Bothfeld, Keith E.J. Tyo