Patents by Inventor William H. Chandler, Jr.
William H. Chandler, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230395935Abstract: A method for manufacturing a structure comprising and electrode assembly having a porous electrically insulating material, and first and second endplates, is provided. The electrode assembly comprises a population of unit cells stacked in series in a stacking direction, opposing first and second longitudinal end surfaces separated along the stacking direction. First and second endplates are separated in the stacking direction and overlie the first and second longitudinal end surfaces. According to embodiments of the structure, (i) each unit cell comprises an electrode structure, a counter-electrode structure, and an electrically insulating separator between the electrode and counter-electrode structures, (ii) the electrode structures, counter-electrode structures and electrically insulating separators within each unit cell have opposing first and second vertical end surfaces separated in a vertical direction, and (iii) the vertical direction is orthogonal to the stacking direction.Type: ApplicationFiled: August 17, 2023Publication date: December 7, 2023Inventors: William H. CHANDLER, JR., Robert S. BUSACCA, Bruno A. VALDES, Kim Han LEE, Anthony CALCATERRA, Miles A. M. KOOL, Robert KINCHEN
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Patent number: 11777174Abstract: A method for manufacturing a structure comprising and electrode assembly having a porous electrically insulating material, and first and second endplates, is provided. The electrode assembly comprises a population of unit cells stacked in series in a stacking direction, opposing first and second longitudinal end surfaces separated along the stacking direction. First and second endplates are separated in the stacking direction and overlie the first and second longitudinal end surfaces. According to embodiments of the structure, (i) each unit cell comprises an electrode structure, a counter-electrode structure, and an electrically insulating separator between the electrode and counter-electrode structures, (ii) the electrode structures, counter-electrode structures and electrically insulating separators within each unit cell have opposing first and second vertical end surfaces separated in a vertical direction, and (iii) the vertical direction is orthogonal to the stacking direction.Type: GrantFiled: October 31, 2022Date of Patent: October 3, 2023Assignee: Enovix CorporationInventors: William H. Chandler, Jr., Robert S. Busacca, Bruno A. Valdes, Kim Han Lee, Anthony Calcaterra, Miles A. M. Kool, Robert Kinchen
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Patent number: 7848848Abstract: A robotic system with a common software and hardware platform for integration of a variety of modular components is provided that can be set up for a given application and reconfigured to address changing needs. Modules attach to the robotic platform with standard interfaces in order to maximize the platform's flexibility. Robotic arms also have interchangeability such as variable pitched Z-racks, powder handling or other technologies. The standard interfaces allow third party developers to develop and integrate their own custom modules. One module included with the robotic platform in accord with this invention is a module that both weighs and images a sample.Type: GrantFiled: April 27, 2007Date of Patent: December 7, 2010Assignee: Freeslate, Inc.Inventors: Robert S. Busacca, Jeff Maag, William H. Chandler, Jr., Eric D. Carlson
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Publication number: 20100080733Abstract: A needle assembly has at least one guide member supported by a first body for sliding movement between an extended position and a retracted position. A second body is attached to the guide member. A biasing member biases the guide member to the extended position. A liquid handling needle is coupled to the first body so sliding movement of the guide member toward the retracted position retracts the second body relative to the liquid handling needle. The second body is adapted to contact a sealed receptacle. The biasing member urges the guide member toward said extended position during insertion and during said removal of the needle from the receptacle whereby the second body remains in contact with the sealed receptacle as the guide member moves from its extended position to its retracted position during said insertion and from its retracted position to its extended position during said removal.Type: ApplicationFiled: June 22, 2009Publication date: April 1, 2010Applicant: SYMYX TECHNOLOGIES, INC.Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, JR., Peter J. Desrosiers, J. Christopher Freitag, John F. Varni
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Patent number: 7549978Abstract: A needle assembly has a first body and a guide rod supported for sliding movement between an extended position and a retracted position. A second body is attached to the guide rod. The second body is relatively farther from the first body when the guide rod is in the extended position and relatively closer to the first body when the guide rod is in the retracted position. The guide rod is biased to the extended position. The second body supports a venting needle that extends beyond the second body by a fixed length. A liquid handling needle is coupled to the first body. Sliding movement of the guide rod toward the retracted position retracts the second body and the venting needle relative to the liquid handling needle.Type: GrantFiled: May 16, 2005Date of Patent: June 23, 2009Assignee: Symyx Technologies, Inc.Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, Jr., Peter J. Desrosiers, J. Christopher Freitag, John F. Varni
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Publication number: 20090120169Abstract: A fluid sensor has an electrically grounded header and a plurality of feedthrough conductors extending through the header between opposite ends of the header. The feedthrough conductors are connected to a piezoelectric tuning fork resonator. A temperature sensor is adjacent the tuning fork resonator. A shroud partially encloses the tuning fork resonator and temperature sensor. A printed circuit board is in conductive electrical contact with the feedthrough conductors. The printed circuit board includes an ASIC chip operable to transmit a variable frequency signal to the tuning fork resonator through the feedthrough conductors to oscillate the tuning fork resonator and to monitor impedance of the tuning fork resonator as a function of frequency. The ASIC chip is spaced from the feedthrough conductors a distance of no more than about 2 mm. The printed circuit board is spaced from the tuning fork a distance of no more than about 20 mm.Type: ApplicationFiled: November 12, 2007Publication date: May 14, 2009Inventors: William H. Chandler,, JR., Douglas B. McNeil, Gregory Ray Goslin
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Patent number: 7172732Abstract: An apparatus and method for synthesis and screening of materials are disclosed. According to one aspect of the present invention, a parallel batch reactor for effecting chemical reactions includes a pressure chamber, and a plurality of reaction wells. Each of the reaction wells is in isolatable fluid communication with the pressure chamber such that during a first pressurizing stage of operation, each of the reaction wells can be simultaneously pressurized through common fluid communication with the pressure chamber, and such that during a second reaction stage of operation, each of the reaction wells can be fluidically isolated from at least one other of said plurality of reaction wells.Type: GrantFiled: January 23, 2004Date of Patent: February 6, 2007Assignee: Symyx Technologies, Inc.Inventors: Lynn Van Erden, William H. Chandler, Jr.
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Patent number: 7160513Abstract: An apparatus and method for injection of one or more chemical components into a reaction chamber are disclosed. The apparatus includes a reaction chamber for receiving one or more libraries in a fixed position relative to the chamber and configured to form a sealed enclosure. An injection manifold is located within the reaction chamber and selectively movable relative to the libraries. The injection manifold is configured for receiving at least one fluid transfer line coupled to an external source for injection of one or more chemical components into the reaction chamber.Type: GrantFiled: December 20, 2002Date of Patent: January 9, 2007Assignee: Symyx Technologies, Inc.Inventors: Christopher Goh, Keith Anthony Hall, Thomas R. Boussie, Vince Murphy, Trevor G. Frank, William H. Chandler, Jr., Lynn Van Erden
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Patent number: 7141218Abstract: An apparatus and method for synthesis and screening of materials are disclosed. According to one aspect of the present invention, a parallel batch reactor for effecting chemical reactions includes a pressure chamber, an inlet port, and two or more reaction vessels within the pressure chamber. The inlet port is in fluid communication with the pressure chamber, and is used for pressurizing the pressure chamber from an external pressure source. Each of the two or more reaction vessels are in isolatable fluid communication with the pressure chamber such that during a first pressurizing stage of operation, each of the two or more reaction vessels can be simultaneously pressurized through common fluid communication with the pressure chamber. In addition, during at least a second reaction stage of operation, each of the two or more pressurized reaction vessels can be isolated from each other.Type: GrantFiled: January 21, 2003Date of Patent: November 28, 2006Assignee: Symyx Technologies, Inc.Inventors: Lynn Van Erden, William H. Chandler, Jr.
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Patent number: 7122159Abstract: An apparatus and method for synthesis and screening of materials are disclosed. According to one aspect of the present invention, a parallel batch reactor for effecting chemical reactions includes a pressure chamber, an inlet port, two or more reaction vessels within the pressure chamber, and a reaction vessel cover. The inlet port is in fluid communication with the pressure chamber, and pressurizes the pressure chamber from an external pressure source. Each of the two or more reaction vessels are in isolatable fluid communication with the pressure chamber such that during a first pressurizing stage of operation, each of the two or more reaction vessels can be simultaneously pressurized through common fluid communication with the pressure chamber. In addition, during at least a second reaction stage of operation, each of the two or more pressurized reaction vessels can be isolated from each other by positioning the reaction vessel cover appropriately.Type: GrantFiled: December 12, 2002Date of Patent: October 17, 2006Assignee: Symyx Technologies, Inc.Inventors: Lynn Van Erden, William H. Chandler, Jr.
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Patent number: 7045358Abstract: An apparatus for parallel processing of reaction mixtures, including a reactor block including reaction chambers for containing reaction mixtures under pressure, the reactor block further including a first sidewall, a second sidewall, and a first plurality of fluid flow paths providing fluid communication with the first sidewall and respective reaction chambers and the second sidewall and respective reaction chambers; a stirring system including a base plate defining a second plurality of flow paths, wherein respective flow paths of said second plurality of flow paths are in fluid communication with respective reaction chambers and respective fluid flow paths of said first plurality of flow paths, and the base plate also supports a plurality of stirring blade assemblies for mixing the reaction mixtures; interchangeable manifolds supported by the first sidewall and the second sidewall, the interchangeable manifolds defining a plurality of manifold inlet/outlet ports, wherein respective inlet/outlet ports of saType: GrantFiled: September 19, 2003Date of Patent: May 16, 2006Assignee: Symyx Technologies, Inc.Inventor: William H. Chandler, Jr.
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Patent number: 6939515Abstract: The invention provides methods, apparatus, and systems for performing high-throughput preparation and screening of salts and polymorphs of drug candidates. The invention is directed towards enhancing the pre-formulation discovery process used for drug development. In particular, processes that determine suitable salts and processes that discover substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members based on, for example, a library model generated by a computer system. Another apparatus may filter the synthesized solution to provide a substantially pure mixture that can be subjected to salt or polymorph testing.Type: GrantFiled: May 24, 2002Date of Patent: September 6, 2005Assignee: Symyx Technologies, Inc.Inventors: Eric D. Carlson, Peijun Cong, William H. Chandler, Jr., Peter J. Desrosiers, J. Christopher Freitag, John F. Varni
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Patent number: 6841127Abstract: An apparatus for in-situ injection of one or more chemical components into a reaction chamber is disclosed. The apparatus includes a reaction chamber for receiving one or more libraries, each of the libraries comprising two or more samples. The reaction chamber is configured to form a sealed enclosure. The apparatus further includes an injection manifold supporting injectors for in-situ injection of one or more chemical components onto respective samples of the one or more libraries in the pressurized sealed reaction chamber.Type: GrantFiled: June 28, 2002Date of Patent: January 11, 2005Assignee: Symyx Technologies, Inc.Inventors: Trevor G. Frank, Keith A. Hall, William H. Chandler, Jr., Thomas Boussie, Thomas J. Crevier, Leonid Matsiev, Christopher Goh
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Patent number: 6838052Abstract: An apparatus for in-situ injection of one or more chemical components into a reaction chamber, comprising a reaction chamber for receiving one or more libraries including two or more samples; an injection module in fluid communication with the reaction chamber for permitting in-situ injection of one or more chemical components into the reaction chamber; and a selectively movable transport assembly supported by at least a portion of the reaction chamber for transporting the one or more libraries to the injection module.Type: GrantFiled: June 29, 2001Date of Patent: January 4, 2005Assignee: Symyx Technologies, Inc.Inventors: Trevor G. Frank, Keith A. Hall, William H. Chandler, Jr., Thomas Boussie, Thomas J. Crevier, Leonid F. Matsiev
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Patent number: 6759014Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including slurries, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.Type: GrantFiled: January 26, 2001Date of Patent: July 6, 2004Assignee: Symyx Technologies, Inc.Inventors: G. Cameron Dales, Jonah R. Troth, Kenneth S. Higashihara, Gary Diamond, Vince Murphy, William H. Chandler, Jr., Trevor G. Frank, J. Christopher Freitag
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Patent number: 6692708Abstract: An apparatus for parallel processing of reaction mixtures, including a reactor block including reaction chambers for containing reaction mixtures under pressure, the reactor block further including a first sidewall, a second sidewall, and a first plurality of fluid flow paths providing fluid communication with the first sidewall and respective reaction chambers and the second sidewall and respective reaction chambers; a stirring system including a base plate defining a second plurality of flow paths, wherein respective flow paths of said second plurality of flow paths are in fluid communication with respective reaction chambers and respective fluid flow paths of said first plurality of flow paths, and the base plate also supports a plurality of stirring blade assemblies for mixing the reaction mixtures; interchangeable manifolds supported by the first sidewall and the second sidewall, the interchangeable manifolds defining a plurality of manifold inlet/outlet ports, wherein respective inlet/outlet ports of saType: GrantFiled: April 5, 2001Date of Patent: February 17, 2004Assignee: Symyx Technologies, Inc.Inventor: William H. Chandler, Jr.