Patents by Inventor William H. Harclerode

William H. Harclerode has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6589960
    Abstract: A method for the preparation of a ketone from a narcotic alkaloid having an allyl alcohol moiety is disclosed. The method includes mixing the narcotic alkaloid with an acid in the presence of a catalyst wherein the method is carried out in the substantial absence of hydrogen gas. The method is useful for preparing hydromorphone and hydrocodone compositions having novel impurity profiles. Compositions comprising hydromorphone and hydrocodone are also disclosed.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: July 8, 2003
    Assignee: Abbott Laboratories
    Inventors: William H. Harclerode, Robert Gault, Mark D. Sandison
  • Publication number: 20030045720
    Abstract: A method for the preparation of a ketone from a narcotic alkaloid having an allyl alcohol moiety is disclosed. The method includes mixing the narcotic alkaloid with an acid in the presence of a catalyst wherein the method is carried out in the substantial absence of hydrogen gas. The method is useful for preparing hydromorphone and hydrocodone compositions having novel impurity profiles. Compositions comprising hydromorphone and hydrocodone are also disclosed.
    Type: Application
    Filed: September 27, 2002
    Publication date: March 6, 2003
    Applicant: Abbott Laboratories
    Inventors: William H. Harclerode, Robert Gault, Mark D. Sandison
  • Patent number: 6512117
    Abstract: A method for the preparation of a ketone from a narcotic alkaloid having an allyl alcohol moiety is disclosed. The method includes mixing the narcotic alkaloid with an acid in the presence of a catalyst wherein the method is carried out in the substantial absence of hydrogen gas. The method is useful for preparing hydromorphone and hydrocodone compositions having novel impurity profiles. Compositions comprising hydromorphone and hydrocodone are also disclosed.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: January 28, 2003
    Assignee: Abbott Laboratories
    Inventors: William H. Harclerode, Robert Gault, Mark D. Sandison
  • Patent number: 5240657
    Abstract: A method for making low density (0.8-2 lb/cu.ft.) expanded polymeric products uses blowing agent in an amount of only from 2 to 4.4 weight percent, the process emitting blowing agent during processing in an amount of from only about 0.3 to about 2.5 weight percent. The process uses 2 to 5 expansion steps together with a polymer having a particular polydispersity, weight average molecular weight and M.sub.z :M.sub.n, this polymer having a greater expandability than conventional polymers. The process requires only about half of the amount of blowing agent currently being used in commercially viable processes for making expanded polystyrene products. The process can be used with or without a molding step.
    Type: Grant
    Filed: October 15, 1991
    Date of Patent: August 31, 1993
    Assignee: BASF Corporation
    Inventors: William H. Harclerode, Eugene K. Zimmermann, Barry J. Pekich, John C. Knutsen, John V. Wiman, John C. Voss
  • Patent number: 5115066
    Abstract: A polystyrene polymer as well as an expandable polystyrene formulation comprises a polystyrene polymer having a particular molecular weight distribution. The polymer itself exhibits a polydispersity of from about 1 to less tha 2.0, a weight average molecular weight of greater than about 200,000 to about 300,000, and an M.sub.z :M.sub.n of from about 2 to less than about 3.0. Furthermore, the polystyrene polymer is branched to from 0 to less than 5 weight percent.The expandable polystyrene formulation comprises a polystyrene polymer exhibiting a polydispersity of from about 1.0 to less than 2.5, a weight average molecular weight of from greater than about 180,000 to about 300,000, an M.sub.z :M.sub.n of from about 2 to about 4.5. The polystyrene polymer is present in an amount of from about 94.5 weight percent to about 98 weight percent, based on the total weight of the formulation, and the polystyrene polymer is branched to from 0 to less than 5 weight percent.
    Type: Grant
    Filed: October 15, 1991
    Date of Patent: May 19, 1992
    Assignee: BASF Corporation
    Inventors: Eugene K. Zimmermann, Bernhard Wagner, William E. Volz, William H. Harclerode, John V. Wiman, John C. Voss
  • Patent number: 5114640
    Abstract: A method for making low density (0.8-1.1 lb./cu.ft.) expanded polymeric products uses blowing agent in an amount of any from 2 to 4.4 weight percent and aging periods of from 1 to 80 hours after each expansion step. The process uses 2 to 5 expansion steps and a polymer having a particular polydispersity, weight average molecular weight and M.sub.z :M.sub.n, this polymer having a greater expandability than conventional polymers. The process requires only about half of the amount of blowing currently being used in commercially viable processes for making expanded polystyrene products. The process can be used with or without a molding step.
    Type: Grant
    Filed: October 15, 1991
    Date of Patent: May 19, 1992
    Assignee: BASF Corporation
    Inventors: William H. Harclerode, John C. Knutsen, Barry J. Pekich, John V. Wiman, John C. Voss
  • Patent number: 5112875
    Abstract: A polystyrene polymer as well as an expandable polystyrene formulation comprises a polystyrene polymer having a particular molecular weight distribution. The polymer itself exhibits a polydispersity of from about 1 to less than 2.0, a weight average molecular weight of greater than about 200,000 to about 300,000, and an M.sub.z :M.sub.n of from about 2 to less than about 3.0. Furthermore, the polystyrene polymer is branched to from 0 to less than 5 weight percent.The expandable polystyrene formulation comprises a polystyrene polymer exhibiting a polydispersity of from about 1.0 to less than 2.5, a weight average molecular weight of from greater than about 180,000 to about 300,000, an M.sub.z :M.sub.n of from about 2 to about 4.5. The polystyrene polymer is present in an amount of from about 94.5 weight percent to about 98 weight percent, based on the total weight of the formulation, and the polystyrene polymer is branched to from 0 to less than 5 weight percent.
    Type: Grant
    Filed: November 26, 1990
    Date of Patent: May 12, 1992
    Assignee: BASF Corporation
    Inventors: Eugene K. Zimmermann, Bernhard Wagner, William E. Volz, William H. Harclerode, John V. Wiman, John C. Voss
  • Patent number: 5110836
    Abstract: A method for making low density (0.8-1.1 lb/cu.ft.) expanded polymeric products uses blowing agent in an amount of only from 2 to 4.4 weight percent and aging periods of from 1 to 80 hours after each expansion step. The process uses 2 to 5 expansion steps and a polymer having a particular polydispersity, weight average molecular weight and M.sub.z :M.sub.n, this polymer having a greater expandability than conventional polymers. The process requires only about half of the amount of blowing agent currently being used in commerically viable processes for making expanded polystyrene products. The process can be used with or without a molding step.
    Type: Grant
    Filed: November 26, 1990
    Date of Patent: May 5, 1992
    Assignee: BASF Corporation
    Inventors: William H. Harclerode, John C. Knutsen, Barry J. Pekich, John V. Wiman, John C. Voss
  • Patent number: 5110524
    Abstract: A method for making low density (0.8-1.1 lb/cu. ft.) expanded polymeric products uses blowing agent in an amount of only from 2 to 4.4 weight percent. The process uses 2 to 5 expansion steps together with a polymer having a particular polydispersity, weight average molecular weight and M.sub.z :M.sub.n, this polymer having a greater expandability than conventional polymers. The process requires only about half of the amount of blowing agent currently being used in commercially viable processes for making expanded polystyrene products. The process can be used with or without a molding step.
    Type: Grant
    Filed: October 15, 1991
    Date of Patent: May 5, 1992
    Assignee: BASF Corporation
    Inventors: William H. Harclerode, William E. Volz, John V. Wiman, John C. Voss, Barry J. Pekich, John C. Knutsen
  • Patent number: 5110837
    Abstract: A method for making low density (0.8-1.1 lb/cu.ft.) expanded polymeric products uses blowing agent in an amount of only from 2 to 4.4 weight percent. The process uses 2 to 5 expansion steps together with a polymer having a particular polydispersity, weight average molecular weight and M.sub.z :M.sub.n, this polymer having a greater expandability than conventional polymers. The process requires only about half of the amount of blowing agent currently being used in commercially viable processes for making expanded polystyrene products. The process can be used with or without a molding step.
    Type: Grant
    Filed: November 26, 1990
    Date of Patent: May 5, 1992
    Assignee: BASF Corporation
    Inventors: William H. Harclerode, William E. Volz, John V. Wiman, John C. Voss, Barry J. Pekich, John C. Knutsen
  • Patent number: 5086078
    Abstract: A method for making low density (0.8-2 lb/cu.ft.) expanded polymeric products uses blowing agent in an amount of only from 2 to 4.4 weight percent, the process emitting blowing agent during processing in an amount of from only about 0.3 to about 2.5 weight percent. The process uses 2 to 5 expansion steps together with a polymer having a particular polydispersity, weight average molecular weight and M.sub.z :M.sub.n, this polymer having a greater expandability than conventional polymers. The process requires only about half of the amount of blowing agent currently being used in commerically viable processes for making expanded polystyrene products. The process can be used with or without a molding step.
    Type: Grant
    Filed: November 26, 1990
    Date of Patent: February 4, 1992
    Assignee: BASF Corporation
    Inventors: William H. Harclerode, Eugene K. Zimmermann, Barry J. Pekich, John C. Knutsen, John V. Wiman, John C. Voss