Patents by Inventor William H. Moser
William H. Moser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140206788Abstract: Addition-fragmentation agents of the formula are disclosed having the following functional groups: 1) a labile addition-fragmentation group that can cleave and reform to relieve strain, 2) a free-radically polymerizable group, and 3) a surface-modifying functional group that associates with the surface of a substrate.Type: ApplicationFiled: August 14, 2012Publication date: July 24, 2014Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Guy D. Joly, Ahmed S. Abuelyaman, Bradley D. Craig, Afshin Falsafi, Joel D. Oxman, Larry R. Krepski, William H. Moser, Serkan Yurt, Ann R. Fornof
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Patent number: 8697873Abstract: Imidazopyridine, imidazoquinoline, and imidazonaphthyridine compounds having an amide substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.Type: GrantFiled: March 24, 2005Date of Patent: April 15, 2014Assignee: 3M Innovative Properties CompanyInventors: Larry R. Krepski, Joseph F. Dellaria, Jr., Daniel E. Duffy, David T. Amos, Bernhard M. Zimmermann, William H. Moser
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Publication number: 20130316307Abstract: Dental compositions are described comprising an addition-fragmentation agent comprising at least one ethylenically unsaturated terminal group and a backbone unit comprising an ?,?-unsaturated carbonyl; at least one monomer comprising at least two ethylenically unsaturated group; and inorganic oxide filler. The addition-fragmentation agent is preferably free-radically cleavable. The addition-fragmentation agent preferably comprises at least two ethylenically unsaturated terminal groups, such as (meth)acTylate groups. In some embodiments, the addition-fragmentation agent has the formula: wherein R1, R2 and R3 are each independently Zm, -Q-, a (hetero)alkyl group or a (hetero)aryl group with the proviso that at least one of R1, R2 and R3 is Zm-Q-; Q is a linking group have a valence of m+1; Z is an ethylenically unsaturated polymerizable group; m is 1 to 6; each X1 is independently —O— or —NR4—, where R4 is H or C1-C4 alkyl; and n is 0 or 1.Type: ApplicationFiled: February 8, 2012Publication date: November 28, 2013Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Guy D. Joly, Larry R. Krepski, Babu N. Gaddam, Ahmed S. Abuelyaman, Bradley D. Craig, Timothy D. Dunbar, Chuntao Cao, Joel D. Oxman, Afshin Falsafi, William H. Moser, Hoa T. Bui
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Publication number: 20120121651Abstract: Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, and prodrugs thereof, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.Type: ApplicationFiled: January 26, 2012Publication date: May 17, 2012Inventors: David S. Hays, Michael E. Danielson, John F. Gerster, Shri Niwas, Ryan B. Prince, Tushar A. Kshirsagar, Philip D. Heppner, William H. Moser, Joan T. Moseman, Matthew R. Radmer, Maureen A. Kavanagh, Sarah A. Strong, Jason D. Bonk
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Patent number: 8168802Abstract: Methods and intermediates useful for making compounds of the formula: and the preparation of compounds of Formula I, preferably including the formation of intermediate compounds of the formula:Type: GrantFiled: March 31, 2006Date of Patent: May 1, 2012Assignee: 3M Innovative Properties CompanyInventors: David S. Hays, Sonja S. Mackey, William H. Moser, Doris D. Stoermer, Matthew R. Radmer, Shri Niwas
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Patent number: 8138173Abstract: Pyrazolo[3,4-c]quinolines, pyrazolo[4,5-c]naphthyridines, and analogs thereof, eg., 6,7,8,9-tetrahydro pyrazolo[3,4-c]quinolines, and, pharmaceutical compositions containing the compounds, intermediates, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inhibiting cytokine biosynthesis in animals and in the therapeutic or prophylactic treatment of diseases by inhibiting cytokine biosynthesis are disclosed.Type: GrantFiled: March 31, 2006Date of Patent: March 20, 2012Assignee: 3M Innovative Properties CompanyInventors: Bryon A. Merrill, Michael E. Danielson, David S. Hays, David T. Amos, Philip D. Heppner, Tushar A. Kshirsagar, Gregory D. Lundquist, Jr., William H. Moser
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Publication number: 20120035209Abstract: Hydroxy substituted 1H-imidazo[4,5-c]pyridin-4-amines, with a hydroxy substituent at the 2-position, pharmaceutical compositions containing these compounds, methods of making the compounds, intermediates, and methods of use of these compounds as immunomodulators for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.Type: ApplicationFiled: October 20, 2011Publication date: February 9, 2012Applicant: PFIZER INC.Inventors: Joseph F. Dellaria, JR., William H. Moser, Matthew R. Radmer, George W. Griesgraber
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Publication number: 20110269965Abstract: Methods and intermediates useful for making compounds of the formula: and the preparation of compounds of Formula I, preferably including the formation of intermediate compounds of the formula:Type: ApplicationFiled: March 31, 2006Publication date: November 3, 2011Applicant: Coley Pharmaceutical Group, Inc.Inventors: David S. Hays, Sonja S. Mackey, William H. Moser, Doris D. Stoermer, Matthew R. Radmer, Shri Niwas
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Patent number: 7939526Abstract: Imidazo ring compounds (e.g., imidazoquinolines, 6,7,8,9-tetrahydroimidazoquinolines, imidazonaphthyridines, and 6,7,8,9-tetrahydroimidazonaphthyridines) with a sulfide-, sulfinyl-, or sulfonyl-containing ether substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, methods of making the compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.Type: GrantFiled: December 3, 2004Date of Patent: May 10, 2011Assignee: 3M Innovative Properties CompanyInventors: Matthew R. Radmer, William H. Moser, Joan T. Moseman, Joseph F. Dellaria, Jr.
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Patent number: 7915281Abstract: Imidazo ring compounds, (e.g. imidazo[4,5-c]pyridine, imidazo[4,5-c]quinoline, 6,7,8,9-tetrahydro imidazo[4,5-c]quinoline, and imidazo[4,5-c]naphthyridine compounds) having an isoxazole, dihydroisoxazole, or oxadiazole substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.Type: GrantFiled: June 17, 2005Date of Patent: March 29, 2011Assignee: 3M Innovative Properties CompanyInventors: William H. Moser, Joan T. Moseman, Tushar A. Kshirsagar, Philip D. Heppner
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Patent number: 7879849Abstract: Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, and 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.Type: GrantFiled: June 8, 2009Date of Patent: February 1, 2011Assignee: 3M Innovative Properties CompanyInventors: David S. Hays, Michael E. Danielson, John F. Gerster, Shri Niwas, Ryan B. Prince, Tushar A. Kshirsagar, Philip D. Heppner, William H. Moser, Joan T. Moseman, Matthew R. Radmer, Maureen A. Kavanagh, Sarah A. Strong, Jason D. Bonk
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Publication number: 20100152230Abstract: Hydroxy substituted 1H-imidazo[4,5-c]pyridin-4-amines, with a hydroxy substituent at the 2-position, pharmaceutical compositions containing these compounds, methods of making the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.Type: ApplicationFiled: September 1, 2006Publication date: June 17, 2010Inventors: Joseph F. Dellaria, JR., William H. Moser, Matthew R. Radmer, George W. Gries-Graber
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Publication number: 20090318435Abstract: Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, and 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.Type: ApplicationFiled: June 8, 2009Publication date: December 24, 2009Inventors: David S. Hays, Michael E. Danielson, John F. Gerster, Shri Niwas, Ryan B. Prince, Tushar A. Kshirsagar, Philip D. Heppner, William H. Moser, Joan T. Moseman, Matthew R. Radmer, Maureen A. Kavanagh, Sarah A. Strong, Jason D. Bonk
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Patent number: 7544697Abstract: Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, and 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.Type: GrantFiled: April 1, 2005Date of Patent: June 9, 2009Assignee: Coley Pharmaceutical Group, Inc.Inventors: David S. Hays, Michael E. Danielson, John F. Gerster, Shri Niwas, Ryan B. Prince, Tushar A. Kshirsagar, Philip D. Heppner, William H. Moser, Joan T. Moseman, Matthew R. Radmer, Maureen A. Kavanagh, Sarah A. Strong, Jason D. Bonk
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Publication number: 20090075980Abstract: Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, and prodrugs thereof, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.Type: ApplicationFiled: March 31, 2006Publication date: March 19, 2009Applicant: Coley Pharmaceutical Group, Inc.Inventors: David S. Hays, Michael E. Danielson, John F. Gerster, Shri Niwas, Ryan B. Prince, Tushar A. Kshirsagar, Philip D. Heppner, William H. Moser, Joan T. Moseman, Matthew R. Radmer, Maureen A. Kavanagh, Sarah A. Strong, Jason D. Bonk
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Publication number: 20090069299Abstract: Pyrazolo[3,4-c]quinolines, pyrazolo[4,5-c]naphthyridines, and analogs thereof, eg., 6,7,8,9-tetrahydro pyrazolo[3,4-c]quinolines, and, pharmaceutical compositions containing the compounds, intermediates, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inhibiting cytokine biosynthesis in animals and in the therapeutic or prophylactic treatment of diseases by inhibiting cytokine biosynthesis are disclosed.Type: ApplicationFiled: March 31, 2006Publication date: March 12, 2009Applicant: Coley Pharmaceutical Group, Inc.Inventors: Bryon A. Merrill, Michael E. Danielson, David S. Hays, David T. Amos, Philip D. Heppner, Tushar A. Kshirsagar, Gregory D. Lundquist, JR., William H. Moser
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Patent number: 7220758Abstract: Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.Type: GrantFiled: July 24, 2006Date of Patent: May 22, 2007Assignee: 3M Innovative Properties CompanyInventors: Joseph F. Dellaria, Kyle J. Lindstrom, Luke T. Dressel, Philip D. Heppner, John R. Jacobsen, Joan T. Moseman, William H. Moser, Matthew R. Radmer, Doris Stoermer
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Patent number: 7125890Abstract: Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.Type: GrantFiled: August 11, 2004Date of Patent: October 24, 2006Assignee: 3M Innovative Properties CompanyInventors: Joseph F. Dellaria, Kyle J. Lindstrom, Luke T. Dressel, Daniel E. Duffy, Philip D. Heppner, John R. Jacobsen, Joan T. Moseman, William H. Moser, Matthew R. Radmer, Doris Stoermer, Bernhard M. Zimmermann
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Publication number: 20040010007Abstract: Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.Type: ApplicationFiled: June 6, 2003Publication date: January 15, 2004Inventors: Joseph F. Dellaria, Kyle J. Lindstrom, Luke T. Dressel, Daniel E. Duffy, Philip D. Heppner, John R. Jacobsen, Joan T. Moseman, William H. Moser, Matthew R. Radmer, Doris Stoermer, Bernhard M. Zimmermann
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Patent number: 5316133Abstract: A movable floor mechanism (10) is adapted for placement in the bed of a truck. The mechanism includes a frame (12, 14, 16), a movable floor (26) encircling the frame, a motor (24) attached to the frame, and at least one sprocket (22) attached to the motor, the sprocket engaging the movable floor. The frame is made from a pair of longitudinal beams (12), a plurality of lateral beams (14) attached between the longitudinal beams, and at least one guide rail (16) attached to the lateral beams. The movable floor (26) is made from a plurality of interengaged floor elements (26a, 26b). Each of the floor elements is made from a central portion, a connector, and a receptor, wherein the receptor is configured to accept the connector of an adjacent floor element. The receptor contains an axial slot (52) and the connector contains a pin receiving hole (56). When two floor elements are engaged the axial slot of the first floor element and pin receiving hole of the second floor element align to receive a pin (54).Type: GrantFiled: June 3, 1993Date of Patent: May 31, 1994Assignee: Mosermatic, Inc.Inventor: William H. Moser