Abstract: Evanescently-coupled planar waveguides for enhancing total internal reflection fluorescence microscopy are disclosed. The waveguides include multiple thin layers of one or more materials on a cover slip arranged resonantly enhance the optical field at the surface of the layer stack by evanescently coupling to a leaky guided mode.

Abstract: Evanescently-coupled planar waveguides for enhancing total internal reflection fluorescence microscopy are disclosed. The waveguides include multiple thin layers of one or more materials on a cover slip arranged resonantly enhance the optical field at the surface of the layer stack by evanescently coupling to a leaky guided mode.

Abstract: An assembly for a door of a motor vehicle includes a window molding having an end portion including an edge. The window molding includes opposing inboard and outboard legs defining a channel therebetween. The assembly also includes an appliqué extending between an upper and a lower end. The appliqué includes an end cap integrally formed at the lower end. The end cap abuts the edge of the end portion to close out the window molding.

Abstract: A bullet-resistant back extender includes an armor carrier having an inner pocket with a bullet-resistant ballistic panel disposed within the inner pocket and an upper portion of the armor carrier having a fastener to attach the bullet-resistant back extender to a fastener in a bullet-resistant vest.

Abstract: Disclosed herein are methods for detecting and identifying potential breast cancer biomarkers in an individual patient. Also disclosed are newly discovered breast cancer markers set forth in Tables I, II and III, associated with the cancerous state of breast cells. It has been discovered that a higher than normal level of expression of any of these markers or combination of these markers correlates with breast cancer in a patient. Methods are provided for detecting the presence of breast cancer in a sample, the absence of breast cancer in a sample, the stage of breast cancer, assessing whether a breast cancer has metastasized, predicting the likely clinical outcome of a breast cancer patient, and with other characteristics of breast cancer that are relevant to prevention, diagnosis, characterization, and therapy of breast cancer in a patient.

Abstract: A method or platform for monoclonal antibody based biomarker discovery is disclosed. The method according to the invention provides for the integration of analyte collection, hybridoma screening and nanovolume integrated mass spectrometry (NVIMS) to achieve a robust screening system that is capable, for example, of cutting 4-6 years off of the classical biomarker discovery and development process. The invention provides a platform for the rapid, high-throughput production, isolation and characterization of, e.g., disease specific biomarkers together with highly specific monoclonal antibodies. The method of the invention has a variety of applications such as, but not limited to, drug testing, biohazard applications, ecological applications, physiological applications and/or pathology screening applications. The method of the invention is also capable of being performed or used as or with a high-throughput screening process or system of the invention.

Abstract: A multi-tiered lookup table is used to progressively map a virtual address to a specific control word that facilitates resolution of the virtual address for a translation lookaside buffer (TLB) miss. In one embodiment, the control word has a compressed and efficiently encoded image of the TLB hardware register data. The control word is accessed with or without a level of indirection in various embodiments. In some embodiments, the control word provides all information needed to decode the majority of memory blocks, or points to a third level for special blocks.

Abstract: A graphics processor is provided that includes a linear-output gamma translator, a processor core, and a non-linear gamma translator. The graphics processor facilitates improved performance by translating image data into a linear gamma space for processing and rendering, and then translating rendered image data into non-linear gamma space for output to the display. The graphics processor uses the translated linear gamma space image data during internal pixel operations, resulting in superior rendering performance. Furthermore, because image data is translated into linear gamma space in the graphics processor, image data from different sources having different gamma representations can be more efficiently and accurately merged. The rendered image data is then translated to a non-linear gamma space and is outputted to the display device.

Abstract: A graphics driver and method is provided that facilitates graphics rendering time partitioning to provide improved resource allocation between multiple windows and/or multiple graphics clients. The graphics driver receives high level graphics data from multiple graphics clients and outputs a time-partitioned chain of graphics primitives to the graphics processor. The graphics driver includes a partitioning controller, a graphics translator, and a chain builder. The partitioning controller allocates processing time among the multiple graphics clients, with each of the multiple graphics clients being allocated a periodic budget. The graphics translator translates high level graphics commands received from the graphics clients into graphics primitives that can be processed by the graphics processor. The chain builder creates chains of the graphics primitives that are configured to give each graphics client its associated periodic budget in the graphics processor.

Abstract: An apparatus includes a rendering engine to render a foreground of an image. The apparatus also includes a logic, separate from the rendering engine, to merge at least one background color with the foreground of the image.

Abstract: High fidelity arcs are produced using a set of interconnected trapezoids, which are transmitted in a highly efficient triangle mesh to a graphics rendering device. Perspective correction capabilities of a graphics engine are used to map a small rectangular texture patch onto the trapezoids, such that the circle appears completely smooth. Anti-aliasing line profiles are applied such that super-sampling is only required in a single dimension.

Abstract: A multi-tiered lookup table is used to progressively map a virtual address to a specific control word that facilitates resolution of the virtual address for a translation lookaside buffer (TLB) miss. In one embodiment, the control word has a compressed and efficiently encoded image of the TLB hardware register data. The control word is accessed with or without a level of indirection in various embodiments. In some embodiments, the control word provides all information needed to decode the majority of memory blocks, or points to a third level for special blocks.