Patents by Inventor William Harries

William Harries has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Treating Endocrine Diseases and Disorders
    Publication number: 20260077021
    Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, which modulate insulin secretion, suppress appetite, and reduce body mass by activating G-protein coupled receptors (GPCRs), such as ectopic olfactory receptors, and transient receptor potential (TRP) ion channels. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes and obesity.
    Type: Application
    Filed: November 20, 2025
    Publication date: March 19, 2026
    Inventors: Christopher Hanson, William Harries, Bradley Brown
  • Method of making an aromagraph comprising ectopic olfactory receptors
    Patent number: 12474324
    Abstract: Biosensors are disclosed for detecting ligand binding at ectopic Olfactory Receptors. Methods of identifying novel ectopic Olfactory Receptors are also disclosed. Ligands for ectopic Olfactory Receptors are disclosed as well as methods for using these ligands to interact with ectopic Olfactory Receptors, including the use of such ligands in the treatment and/or mitigation of disease conditions.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: November 18, 2025
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventors: Chris Hanson, William Harries
  • Compositions and Methods for Treating Hypertension by Modulating Endocrine Activity
    Publication number: 20250295623
    Abstract: Disclosed herein are compounds and ligands, and antihypertensive compositions formed therewith, that modulate seminal endocrine factors that control blood pressure and, thereby, treat hypertension. Also disclosed herein are methods for using the antihypertensive compositions to treat hypertension and disorders associated therewith.
    Type: Application
    Filed: November 25, 2024
    Publication date: September 25, 2025
    Inventors: Christopher Hanson, William Harries
  • Compositions and methods for treating endocrine diseases and disorders
    Patent number: 12290550
    Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.
    Type: Grant
    Filed: December 13, 2024
    Date of Patent: May 6, 2025
    Assignee: Olfactive Ai, Inc.
    Inventors: Christopher Hanson, William Harries
  • Compositions and methods for treating hypertension by modulating endocrine activity
    Patent number: 12186299
    Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate seminal endocrine factors that control blood pressure and, thereby, treat hypertension. Also disclosed herein are methods for using the compositions to treat hypertension and disorders associated therewith.
    Type: Grant
    Filed: August 21, 2024
    Date of Patent: January 7, 2025
    Assignee: Olfactive Biosolutions, LLC
    Inventors: Christopher Hanson, William Harries
  • Compositions and methods for treating endocrine diseases and disorders
    Patent number: 12171727
    Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.
    Type: Grant
    Filed: August 19, 2024
    Date of Patent: December 24, 2024
    Assignee: Olfactive Biosolutions, LLC
    Inventors: Christopher Hanson, William Harries
  • Compositions and methods for treating endocrine diseases and disorders
    Patent number: 12115134
    Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.
    Type: Grant
    Filed: February 2, 2024
    Date of Patent: October 15, 2024
    Assignee: Olfactive Biosolutions, LLC
    Inventors: Christopher Hanson, William Harries
  • Compositions and methods for treating endocrine diseases and disorders
    Patent number: 12102664
    Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.
    Type: Grant
    Filed: March 25, 2024
    Date of Patent: October 1, 2024
    Assignee: Olfactive Biosolutions, LLC
    Inventors: Christopher Hanson, William Harries
  • Compositions and methods for treating hypertension by modulating endocrine activity
    Patent number: 12102611
    Abstract: Disclosed herein are compounds and ligands, and antihypertensive compositions formed therewith, that modulate seminal endocrine factors that control blood pressure and, thereby, treat hypertension. Also disclosed herein are methods for using the antihypertensive compositions to treat hypertension and disorders associated therewith.
    Type: Grant
    Filed: March 25, 2024
    Date of Patent: October 1, 2024
    Assignee: Olfactive Biosolutions, LLC
    Inventors: Christopher Hanson, William Harries
  • Compositions and Methods for Treating Hypertension by Modulating Endocrine Activity
    Publication number: 20240269100
    Abstract: Disclosed herein are compounds and ligands, and antihypertensive compositions formed therewith, that modulate seminal endocrine factors that control blood pressure and, thereby, treat hypertension. Also disclosed herein are methods for using the antihypertensive compositions to treat hypertension and disorders associated therewith.
    Type: Application
    Filed: March 25, 2024
    Publication date: August 15, 2024
    Inventors: Christopher Hanson, William Harries
  • Compositions and Methods for Treating Endocrine Diseases and Disorders
    Publication number: 20240226240
    Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.
    Type: Application
    Filed: March 25, 2024
    Publication date: July 11, 2024
    Inventors: Christopher Hanson, William Harries
  • COMPOSITIONS AND METHODS FOR TREATING ENDOCRINE DISEASES AND DISORDERS
    Publication number: 20240165061
    Abstract: Disclosed herein are compounds and ligands, and compositions formed therewith, that modulate insulin secretion and suppress appetite by activating ectopic olfactory receptors. Also disclosed herein are methods for using the compositions to treat endocrine diseases, such as type-2 diabetes, and disorders, such as abnormal insulin secretion.
    Type: Application
    Filed: February 2, 2024
    Publication date: May 23, 2024
    Inventors: Christopher Hanson, William Harries
  • BIOSENSOR FOR DETECTING SMELL, SCENT, AND TASTE
    Publication number: 20230108448
    Abstract: The invention relates to biosensors for detecting odorants, especially a biosensor that mimics odorant detection by a mammal, for example, humans, dogs or cats. The field of the invention also related to the standardization of odors for scent, smell and taste using the biosensor of the invention, and the discovery of agonists, antagonists, and mixtures of odorants for creating new odors, masking odors, enhancing odors, and designing odors.
    Type: Application
    Filed: May 12, 2022
    Publication date: April 6, 2023
    Inventors: Chris HANSON, William HARRIES, Victor Todd CUSHMAN, Ed COSTELLO
  • Biosensor for detecting smell, scent, and taste
    Patent number: 11460469
    Abstract: The invention relates to biosensors for detecting odorants, especially a biosensor that mimics odorant detection by a mammal, for example, humans, dogs or cats. The field of the invention also related to the standardization of odors for scent, smell and taste using the biosensor of the invention, and the discovery of agonists, antagonists, and mixtures of odorants for creating new odors, masking odors, enhancing odors, and designing odors.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: October 4, 2022
    Assignee: Aromyx Corporation
    Inventors: Chris Hanson, William Harries, Victor Todd Cushman, Ed Costello
  • SCENT, SMELL AND ODOR CREATION FROM AN AROMAGRAPH
    Publication number: 20220145212
    Abstract: Disclosed here are methods and apparati for making a desired scent, smell, odor, aroma, and/or taste. Also disclosed herein are methods and apparati for making a scent, smell, odor, aroma, and/or taste that will produce a desired response in a desired group of subjects.
    Type: Application
    Filed: January 28, 2022
    Publication date: May 12, 2022
    Inventors: Chris HANSON, William HARRIES, Victor Todd CUSHMAN, Ed COSTELLO
  • ECTOPIC OLFACTORY RECEPTORS AND USES THEREOF
    Publication number: 20220099657
    Abstract: Biosensors are disclosed for detecting ligand binding at ectopic Olfactory Receptors. Methods of identifying novel ectopic Olfactory Receptors are also disclosed. Ligands for ectopic Olfactory Receptors are disclosed as well as methods for using these ligands to interact with ectopic Olfactory Receptors, including the use of such ligands in the treatment and/or mitigation of disease conditions.
    Type: Application
    Filed: May 5, 2021
    Publication date: March 31, 2022
    Inventors: Chris HANSON, William HARRIES
  • Biosensor for detecting smell, scent, and taste
    Patent number: 11092599
    Abstract: The invention relates to biosensors for detecting odorants, especially a biosensor that mimics odorant detection by a mammal, for example, humans, dogs or cats. The field of the invention also related to the standardization of odors for scent, smell and taste using the biosensor of the invention, and the discovery of agonists, antagonists, and mixtures of odorants for creating new odors, masking odors, enhancing odors, and designing odors.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: August 17, 2021
    Assignee: Aromyx Corporation
    Inventors: Chris Hanson, William Harries, Victor Todd Cushman, Ed Costello
  • Ectopic olfactory receptors and uses thereof
    Patent number: 11009502
    Abstract: Biosensors are disclosed for detecting ligand binding at ectopic Olfactory Receptors. Methods of identifying novel ectopic Olfactory Receptors are also disclosed. Ligands for ectopic Olfactory Receptors are disclosed as well as methods for using these ligands to interact with ectopic Olfactory Receptors, including the use of such ligands in the treatment and/or mitigation of disease conditions.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: May 18, 2021
    Assignee: Aromyx Corporation
    Inventors: Chris Hanson, William Harries
  • BIOSENSOR FOR DETECTING SMELL, SCENT, AND TASTE
    Publication number: 20200003774
    Abstract: The invention relates to biosensors for detecting odorants, especially a biosensor that mimics odorant detection by a mammal, for example, humans, dogs or cats. The field of the invention also related to the standardization of odors for scent, smell and taste using the biosensor of the invention, and the discovery of agonists, antagonists, and mixtures of odorants for creating new odors, masking odors, enhancing odors, and designing odors.
    Type: Application
    Filed: September 16, 2019
    Publication date: January 2, 2020
    Inventors: Chris HANSON, William HARRIES, Victor Todd CUSHMAN, Ed COSTELLO
  • Ectopic Olfactory Receptors and Uses Thereof
    Publication number: 20190293628
    Abstract: Biosensors are disclosed for detecting ligand binding at ectopic Olfactory Receptors. Methods of identifying novel ectopic Olfactory Receptors are also disclosed. Ligands for ectopic Olfactory Receptors are disclosed as well as methods for using these ligands to interact with ectopic Olfactory Receptors, including the use of such ligands in the treatment and/or mitigation of disease conditions.
    Type: Application
    Filed: January 4, 2019
    Publication date: September 26, 2019
    Applicant: Aromyx Corporation
    Inventors: Chris Hanson, William Harries