Abstract: Multispecific binding proteins that bind NKG2D receptor, CD16, and 5T4 are described, as well as pharmaceutical compositions, formulations, and therapeutic methods of the multispecific binding proteins useful for the treatment of cancer.

Abstract: In an embodiment, process for providing a secure remote workspace includes accessing, via a first client application, a remote desktop application. The process includes activating, within the remote desktop, a second client application to provide access to a task. The process includes obtaining user input in connection with executing the task, and transmitting user input information associated with the execution of the task to a server.

Abstract: The present invention is directed to immunoconjugates comprising an antibody or fragment thereof capable of specifically binding to “Disintegrin and Metalloproteinase Domain-containing Protein 9” (“ADAM9”) conjugated to at least one pharmacological agent. The invention particularly concerns such immunoconjugates that are cross-reactive with human ADAM9 and the ADAM9 of a non-human primate (e.g., a cynomolgus monkey). The invention additionally pertains to all such immunoconjugates that comprise a Light Chain Variable (VL) Domain and/or a Heavy Chain Variable (VH) Domain that has been humanized and/or deimmunized so as to exhibit reduced immunogenicity upon administration of such immunoconjugate to a recipient subject. The invention is also directed to pharmaceutical compositions that contain any of such immunoconjugates, and to methods involving the use of any of such immunoconjugates in the treatment of cancer and other diseases and conditions.

Abstract: The present invention is directed to immunoconjugates comprising an antibody or fragment thereof capable of specifically binding to “Disintegrin and Metalloproteinase Domain- containing Protein 9” (“ADAM9”) conjugated to at least one maytansinoid compound. The invention particularly concerns such immunoconjugates that are cross-reactive with human ADAM9 and the ADAM9 of a non-human primate (e.g., a cynomolgus monkey). The invention additionally pertains to all such immunoconjugates that comprise a Light Chain Variable (VL) Domain and/or a Heavy Chain Variable (VH) Domain that has been humanized and/or deimmunized so as to exhibit reduced immunogenicity upon administration of such immunoconjugate to a recipient subject. The invention is also directed to pharmaceutical compositions that contain any of such immunoconjugates, and to methods involving the use of any of such immunoconjugates in the treatment of cancer and other diseases and conditions.

Abstract: In an embodiment, process for providing a secure remote workspace includes accessing, via a first client application, a remote desktop application. The process includes activating, within the remote desktop, a second client application to provide access to a task. The process includes obtaining user input in connection with executing the task, and transmitting user input information associated with the execution of the task to a server.

Abstract: The present disclosure relates to an apparatus and methods for applying a force on a sample. In particular, the present disclosure relates to a stress cell (200) comprising a frame (205); an actuator arrangement (210) coupled to the frame; and a coupler (220) for coupling the actuator arrangement to the sample (230). The coupler (220) includes a first coupler portion connected to the actuator arrangement (210) and a second coupler portion connectable to the sample (230). The first coupler portion is flexibly coupled to the frame. The actuator arrangement (210) comprises a first element (214) having a first variable length and a second element (212) having a second variable length, and is adapted to vary a difference between the first length and the second length to provide the force.

Abstract: The present disclosure relates to an apparatus and methods for applying a force on a sample. In particular, the present disclosure relates to a stress cell (200) comprising a frame (205); an actuator arrangement (210) coupled to the frame; and a coupler (220) for coupling the actuator arrangement to the sample (230). The coupler (220) includes a first coupler portion connected to the actuator arrangement (210) and a second coupler portion connectable to the sample (230). The first coupler portion is flexibly coupled to the frame. The actuator arrangement (210) comprises a first element (214) having a first variable length and a second element (212) having a second variable length, and is adapted to vary a difference between the first length and the second length to provide the force.

Abstract: An apparatus for processing battery electrodes includes: a microwave applicator cavity with slots on opposite ends to allow a continuous sheet to move through the cavity in a first direction; a processing chamber constructed of microwave-transparent material, disposed within the applicator cavity and surrounding the continuous sheet, the processing chamber having slots to allow the continuous sheet to pass through it; a microwave power supply to deliver power to the applicator cavity; a source of heated gas providing a controlled gas flow through the processing chamber in a direction opposite the first direction; and, at least one non-contacting temperature measuring device positioned to measure a surface temperature at a selected location on the continuous sheet as it passes through the processing chamber. The apparatus is particularly suited for removing polar solvents from porous electrode coatings. A related method is also disclosed.

Abstract: An apparatus for processing battery electrodes includes: a microwave applicator cavity with slots on opposite ends to allow a continuous sheet to move through the cavity in a first direction; a processing chamber constructed of microwave-transparent material, disposed within the applicator cavity and surrounding the continuous sheet, the processing chamber having slots to allow the continuous sheet to pass through it; a microwave power supply to deliver power to the applicator cavity; a source of heated gas providing a controlled gas flow through the processing chamber in a direction opposite the first direction; and, at least one non-contacting temperature measuring device positioned to measure a surface temperature at a selected location on the continuous sheet as it passes through the processing chamber. The apparatus is particularly suited for removing polar solvents from porous electrode coatings. A related method is also disclosed.

Abstract: MET is a receptor tyrosine kinase found on the surface of tumor cells. The present invention includes anti-MET antibodies, forms and fragments, having superior physical and functional properties; immunoconjugates, compositions, diagnostic reagents, methods for inhibiting growth, therapeutic methods, improved antibodies and cell lines; and polynucleotides, vectors and genetic constructs encoding same.

Abstract: An axle lift assembly includes a vehicle configured to support a load. A slide assembly has a member that is movable along a longitudinal extent of the vehicle. The slide assembly is operable to secure the member relative to the vehicle at a select position along the longitudinal extent of the vehicle. A swing arm has a first end pivotally coupled with the member and an opposing second end biased away from the vehicle. The swing arm is configured to support a wheel assembly with a tire for contacting a ground surface. An actuator is operably interconnecting the member and the swing arm for raising the wheel assembly toward the vehicle to lift the tire away from the ground surface. The slide assembly and the actuator are configured to respectively adjust longitudinal and vertical positions of the wheel assembly relative to the vehicle for accommodating a condition of the load.

Abstract: An apparatus for processing battery electrodes includes: a microwave applicator cavity with slots on opposite ends to allow a continuous sheet to move through the cavity in a first direction; a processing chamber constructed of microwave-transparent material, disposed within the applicator cavity and surrounding the continuous sheet, the processing chamber having slots to allow the continuous sheet to pass through it; a microwave power supply to deliver power to the applicator cavity; a source of heated gas providing a controlled gas flow through the processing chamber in a direction opposite the first direction; and, at least one non-contacting temperature measuring device positioned to measure a surface temperature at a selected location on the continuous sheet as it passes through the processing chamber. The apparatus is particularly suited for removing polar solvents from porous electrode coatings. A related method is also disclosed.

Abstract: An axle lift assembly includes a vehicle configured to support a load. A slide assembly has a member that is movable along a longitudinal extent of the vehicle. The slide assembly is operable to secure the member relative to the vehicle at a select position along the longitudinal extent of the vehicle. A swing arm has a first end pivotally coupled with the member and an opposing second end biased away from the vehicle. The swing arm is configured to support a wheel assembly with a tire for contacting a ground surface. An actuator is operably interconnecting the member and the swing arm for raising the wheel assembly toward the vehicle to lift the tire away from the ground surface. The slide assembly and the actuator are configured to respectively adjust longitudinal and vertical positions of the wheel assembly relative to the vehicle for accommodating a condition of the load.

Abstract: An axle lift assembly includes a vehicle configured to support a load. A slide assembly has a member that is movable along a longitudinal extent of the vehicle. The slide assembly is operable to secure the member relative to the vehicle at a select position along the longitudinal extent of the vehicle. A swing arm has a first end pivotally coupled with the member and an opposing second end biased away from the vehicle. The swing arm is configured to support a wheel assembly with a tire for contacting a ground surface. An actuator is operably interconnecting the member and the swing arm for raising the wheel assembly toward the vehicle to lift the tire away from the ground surface. The slide assembly and the actuator are operable to respectively adjust longitudinal and vertical positions of the wheel assembly relative to the vehicle for accommodating a condition of the load.

Abstract: A repair clamp assembly is provided which includes a clamp member, a lug, and a bolt. The clamp member is configured to wrap around a pipe. The lug is attached to the clamp member and is configured to tighten the clamp member around a pipe. The bolt engages the lug and is configured to tighten the clamp member around a pipe with the lug. The bolt includes a fastener portion configured to attach to the lug, and a handle spaced apart from the fastener portion. Lastly, the handle is configured to carry and transport the repair clamp assembly when the bolt is attached to the lug. The handle portion may then be selectively removed when the repair clamp is positioned in place or the handle is no longer needed.

Abstract: An axle lift assembly includes a vehicle configured to support a load. A slide assembly has a member that is movable along a longitudinal extent of the vehicle. The slide assembly is operable to secure the member relative to the vehicle at a select position along the longitudinal extent of the vehicle. A swing arm has a first end pivotally coupled with the member and an opposing second end biased away from the vehicle. The swing arm is configured to support a wheel assembly with a tire for contacting a ground surface. An actuator is operably interconnecting the member and the swing arm for raising the wheel assembly toward the vehicle to lift the tire away from the ground surface. The slide assembly and the actuator are operable to respectively adjust longitudinal and vertical positions of the wheel assembly relative to the vehicle for accommodating a condition of the load.

Abstract: An axle lift assembly includes a beam slidably coupled with and extending on a longitudinal extent of a vehicle frame. A trailing arm has a first end pivotably coupled with the beam. An axle is rotatably coupled with an intermediate portion of the trailing arm. An air spring is disposed between a second end of the trailing arm and the beam for absorbing an upward force from the axle. A support bracket extends down from the beam proximate the first end of the trailing arm. A pneumatic actuator is disposed between the support bracket and the trailing arm for raising the axle from a deployed position to a retracted position that substantially eliminates the upward force on the air spring from the axle.

Abstract: An axle lift assembly includes a beam slidably coupled with and extending on a longitudinal extent of a vehicle frame. A trailing arm has a first end pivotably coupled with the beam. An axle is rotatably coupled with an intermediate portion of the trailing arm. An air spring is disposed between a second end of the trailing arm and the beam for absorbing an upward force from the axle. A support bracket extends down from the beam proximate the first end of the trailing arm. A pneumatic actuator is disposed between the support bracket and the trailing arm for raising the axle from a deployed position to a retracted position that substantially eliminates the upward force on the air spring from the axle.

Abstract: An axle lift assembly includes a beam slidably coupled with and extending on a longitudinal extent of a vehicle frame. A trailing arm has a first end pivotably coupled with the beam. An axle is rotatably coupled with an intermediate portion of the trailing arm. An air spring is disposed between a second end of the trailing arm and the beam for absorbing an upward force from the axle. A support bracket extends down from the beam proximate the first end of the trailing arm. A pneumatic actuator is disposed between the support bracket and the trailing arm for raising the axle from a deployed position to a retracted position that substantially eliminates the upward force on the air spring from the axle.

Abstract: An electrode/separator assembly for use in an electrochemical cell includes a porous composite layer having a total thickness in the range of about 4 ?m to about 50 ?m comprising inorganic particles having an average aggregate particle size in the range of about 0.5 ?m to about 6 ?m in an electrochemically stable polymer matrix.