Abstract: The disclosed system and method provide for the automatic assessment of the presence/severity of the sleep problem and its exact nature. The assessment is based on qualitative information about sleep patterns, insomnia-related factors and daytime consequences, as well as quantitative information about sleep patterns measured by a sensor. By combining the different sources of information (subjective as well as objective data), the diagnosis gives more insight into the nature of the sleep problem and is therefore more accurate. Furthermore, the disclosed system may be used to select specific components of the system that are medically relevant to the individual and therefore create a personalized program. The system teaches a selection of self-management skills that could help the individual to better cope with sleep disturbances and target those factors that maintain the problem or make it worse by a particular individual.

Abstract: To form an ionomer-based catalytic layer on a porous substrate, a heat source (40) is used to dry an ionomer-containing spray (46) so that it does not substantially liquid flow on the substrate (14). The ionomer spray (46) may contain a catalyst. A spray (46) of mixed material for forming the catalytic layer is entrained by a gas stream and is heated and directed to a substrate surface (12). For hydrogen/oxygen fuel cells, catalytic material is incorporated into the proton-conducting membrane (56) to convert diffusing oxygen and hydrogen to water to reduce potential loss at the electrodes and maintain hydration of the proton-conducting membrane (56).

Abstract: To form an ionomer-based catalytic layer on a porous substrate, a heat source (40) is used to dry an ionomer-containing spray (46) so that it does not substantially liquid flow on the substrate (14). The ionomer spray (46) may contain a catalyst. A spray (46) of mixed material for forming the catalytic layer is entrained by a gas stream and is heated and directed to a substrate surface (12). For hydrogen/oxygen fuel cells, catalytic material is incorporated into the proton-conducting membrane (56) to convert diffusing oxygen and hydrogen to water to reduce potential loss at the electrodes and maintain hydration of the proton-conducting membrane (56).

Abstract: The invention provides compositions containing an antigen and a TIM targeting molecule. The invention additionally provides a TIM targeting molecule conjugate, for example, a TIM targeting molecule targeted to a therapeutic or diagnostic moiety. The invention additionally provides methods of using such compositions. In one embodiment, the invention provides a method of stimulating an immune response in an individual by administering a composition comprising an antigen and a TIM targeting molecule in a pharmaceutically acceptable carrier. In another embodiment, the invention provides a method of stimulating an immune response in an individual by administering an antigen and a TIM targeting molecule, which can be administered together in a single composition or separately.