Abstract: The present invention provides autoradiography methods and systems for imaging via the detection of alpha particles, beta particles, or other charged particles. Embodiments of the methods and systems provide high-resolution 3D imaging of the distribution of a radioactive probe, such as a radiopharmaceutical, on a tissue sample. Embodiments of the present methods and systems provide imaging of tissue samples by reconstruction of a 3D distribution of a source of particles, such as a radiopharmaceutical. Embodiments of the methods and systems provide tomographic methods including microtomography, macrotomography, cryomicrotomography and cryomacrotomography.

Abstract: The present invention provides autoradiography methods and systems for imaging via the detection of alpha particles, beta particles, or other charged particles. Embodiments of the methods and systems provide high-resolution 3D imaging of the distribution of a radioactive probe, such as a radiopharmaceutical, on a tissue sample. Embodiments of the present methods and systems provide imaging of tissue samples by reconstruction of a 3D distribution of a source of particles, such as a radiopharmaceutical. Embodiments of the methods and systems provide tomographic methods including microtomography, macrotomography, cryomicrotomography and cryomacrotomography.

Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.

Abstract: A proximity beacon signal transmitted by a network device-coupled proximity beacon transmitter is received at a network device. A RSSI reporting message is generated at the network device based on the proximity beacon signal. A position of the network device-coupled proximity beacon transmitter with respect to the network device is determined using the RSSI reporting message. A location of the network device within a region is determined using the RSSI reporting message and network device map data for the region. The location of the network device-coupled proximity beacon transmitter in the region is determined based on the position of the network device-coupled proximity beacon transmitter with respect to the network device and the location of the network device within the region.

Abstract: The present invention provides autoradiography methods and systems for imaging via the detection of alpha particles, beta particles, or other charged particles. Embodiments of the methods and systems provide high-resolution 3D imaging of the distribution of a radioactive probe, such as a radiopharmaceutical, on a tissue sample. Embodiments of the present methods and systems provide imaging of tissue samples by reconstruction of a 3D distribution of a source of particles, such as a radiopharmaceutical. Embodiments of the methods and systems provide tomographic methods including microtomography, macrotomography, cryomicrotomography and cryomacrotomography.

Abstract: A proximity beacon signal transmitted by a network device-coupled proximity beacon transmitter is received at a network device. A RSSI reporting message is generated at the network device based on the proximity beacon signal. A position of the network device-coupled proximity beacon transmitter with respect to the network device is determined using the RSSI reporting message. A location of the network device within a region is determined using the RSSI reporting message and network device map data for the region. The location of the network device-coupled proximity beacon transmitter in the region is determined based on the position of the network device-coupled proximity beacon transmitter with respect to the network device and the location of the network device within the region.

Abstract: The present invention provides autoradiography methods and systems for imaging via the detection of alpha particles, beta particles, or other charged particles. Embodiments of the methods and systems provide high-resolution 3D imaging of the distribution of a radioactive probe, such as a radiopharmaceutical, on a tissue sample. Embodiments of the present methods and systems provide imaging of tissue samples by reconstruction of a 3D distribution of a source of particles, such as a radiopharmaceutical. Embodiments of the methods and systems provide tomographic methods including microtomography, macrotomography, cryomicrotomography and cryomacrotomography.

Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.

Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.

Abstract: A proximity beacon signal transmitted by a network device-coupled proximity beacon transmitter is received at a network device. A RSSI reporting message is generated at the network device based on the proximity beacon signal. A position of the network device-coupled proximity beacon transmitter with respect to the network device is determined using the RSSI reporting message. A location of the network device within a region is determined using the RSSI reporting message and network device map data for the region. The location of the network device-coupled proximity beacon transmitter in the region is determined based on the position of the network device-coupled proximity beacon transmitter with respect to the network device and the location of the network device within the region.

Abstract: A proximity beacon signal transmitted by a network device-coupled proximity beacon transmitter is received at a network device. A RSSI reporting message is generated at the network device based on the proximity beacon signal. A position of the network device-coupled proximity beacon transmitter with respect to the network device is determined using the RSSI reporting message. A location of the network device within a region is determined using the RSSI reporting message and network device map data for the region. The location of the network device-coupled proximity beacon transmitter in the region is determined based on the position of the network device-coupled proximity beacon transmitter with respect to the network device and the location of the network device within the region.

Abstract: A proximity beacon signal transmitted by a network device-coupled proximity beacon transmitter is received at a network device. A RSSI reporting message is generated at the network device based on the proximity beacon signal. A position of the network device-coupled proximity beacon transmitter with respect to the network device is determined using the RSSI reporting message. A location of the network device within a region is determined using the RSSI reporting message and network device map data for the region. The location of the network device-coupled proximity beacon transmitter in the region is determined based on the position of the network device-coupled proximity beacon transmitter with respect to the network device and the location of the network device within the region.

Abstract: The present invention provides methods and systems for 3D imaging of in vivo and ex vivo tissues. The disclosed systems and methods employ an autoradiographic approach where particles emitted by a radioactive composition within the tissue are detected. Once detected, a 3D representation of the source of particles within the tissue is reconstructed for viewing and analysis.

Abstract: The present invention provides methods and systems for 3D imaging of in vivo and ex vivo tissues. The disclosed systems and methods employ an autoradiographic approach where particles emitted by a radioactive composition within the tissue are detected. Once detected, a 3D representation of the source of particles within the tissue is reconstructed for viewing and analysis.

Abstract: The present invention provides autoradiography methods and systems for imaging via the detection of alpha particles, beta particles, or other charged particles. Embodiments of the methods and systems provide high-resolution 3D imaging of the distribution of a radioactive probe, such as a radiopharmaceutical, on a tissue sample. Embodiments of the present methods and systems provide imaging of tissue samples by reconstruction of a 3D distribution of a source of particles, such as a radiopharmaceutical. Embodiments of the methods and systems provide tomographic methods including microtomography, macrotomography, cryomicrotomography and cryomacrotomography.

Abstract: The present invention provides methods and systems for 3D imaging of in vivo and ex vivo tissues. The disclosed systems and methods employ an autoradiographic approach where particles emitted by a radioactive composition within the tissue are detected. Once detected, a 3D representation of the source of particles within the tissue is reconstructed for viewing and analysis.

Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.

Abstract: The present invention provides methods and systems for 3D imaging of in vivo and ex vivo tissues. The disclosed systems and methods employ an autoradiographic approach where particles emitted by a radioactive composition within the tissue are detected. Once detected, a 3D representation of the source of particles within the tissue is reconstructed for viewing and analysis.

Abstract: This disclosure provides radiolabeled compounds that bind to guanylyl cyclase C (GCC) and which can bind cancer cells that express GCC. Exemplary compounds comprise a chelating moiety capable of binding a radioactive atom, a peptide capable of binding GCC, and a linker moiety connecting the two. This disclosure also provides methods of detecting and treating cancer using the compounds described herein.

Abstract: Compositions, methods and transgenic animals for in vivo detection of ectopically expressed sodium iodide symporter (NIS) are provided.