Abstract: A loudspeaker includes a housing; one or more transducers within the housing; and a control system for controlling the one or more transducers. The control system includes a user interface supported by the housing, the user interface having one or more input elements for inputting one or more input parameters. The control system further includes a processor within the housing that is operatively coupled to the user interface and the one or more transducers. The processor is configured to perform an optimization routine in which the processor determines one or more control parameters for the one or more transducers based on the one or more input parameters.

Abstract: The present disclosure is directed to oral dosage forms of TR? agonist VK2809 and methods of preparing the same. The disclosure provides oral dosage forms of VK2809 with improved stability and solubility properties that allow for storage under normal conditions through the use of spray-drying with one or more polymers selected from the group consisting of: polyvinyl pyrrolidone (PVP), polyvinyl pyrrolidinone-vinyl acetate copolymer (PVP-VA), polyvinyl alcohol (PVA), polyacrylic acid (PAA), polyethylene oxide) (PEO), hydroxypropyl cellulose (HPC), hydroxypropyl methyl cellulose (HPMC), copovidone, poloxamer 407, hypromellose acetate succinate (HPMCAS), polyacrylates and combinations thereof.

Abstract: Provided is a sterile, injectable solution comprising: poloxamer 188 and water for injection, wherein the sterile, injectable solution is reduced in sodium and/or substantially sodium-free. Also provided are methods for using the solution.