Abstract: The present invention provides a scalp cooling device, including a covering part for wrapping a patient's scalp and a cooling part disposed within the covering part. This device can wrap around the patient's scalp and provide a cooling effect, causing the blood vessels in the scalp skin to constrict, reducing the blood flow to the scalp hair follicles, thereby reducing the intake of chemotherapeutic drugs by the hair follicles. Additionally, it lowers biochemical activity, thereby reducing the sensitivity of hair follicles to chemotherapy damage, and reduces the metabolic rate of the hair follicles, thus protecting the patient's hair follicles and preventing or mitigating hair loss caused by chemotherapy.

Abstract: This invention generally relates to a novel induced cytoplasmic IVT (ICIVT) composition useful for inducing in-vitro transcription (IVT)-like RNA/mRNA amplification in the cells of interest after transfection in vitro, ex vivo and/or in vivo. The present invention is useful for designing and developing a variety of RNA/mRNA medicines as well as vaccines comprising a mixture of at least a promoter-linked RNA/mRNA-coding DNA (PLRcD) template and another DNA-dependent RNA polymerase (DdRP) mRNA sequence. Preferably, the DdRP mRNA may be selected from the mRNA of T7, T3 and/or SP6 RNA polymerase, or a combination thereof, while the PLRCD template may encode the transcripts of antisense RNA oligonucleotide (aRNA-ASO), small interferring RNA (siRNA), double-stranded RNA (dsRNA), short hairpin RNA (shRNA), microRNA (miRNA)/microRNA precursor (pre-miRNA), long noncoding RNA (lncRNA), messenger RNA (mRNA), and/or self-amplifying RNA/mRNA (saRNA/samRNA), or a combination thereof.

Abstract: A dental implant fixture mount-abutment includes a fixture mount having a coronal end and an internal slot, a tapered cylinder body, a root for internally connecting to a dental implant, and a plurality of engaging jaws protruded from the root for engaging with an internal channel of the dental implant, such that the root forms a male connector for inserting into the internal channel in the dental implant to stabilize the DIFMA in position.

Abstract: A dental implant fixture mount-abutment, comprising a fixture mount is a 2 to 7 mm coronal extension/metal collar at a coronal end for serving as an impression coping, temporary/permanent abutment and fixture mount, wherein the internal slots in said coronal end for receiving the fixture mount driver, wherein the driven channel in said coronal end for receiving a ball impression screw, wherein said the fixture mount has two small flat facets, located on opposite side of the fixture mount, extended between said coronal end and circumferential groove, an abutment which is a taper cylinder body having a shoulder and a circumferential curvature, wherein the shoulder on the abutment portion is a part of the abutment, wherein the circumferential curvature is designed to avoid engaging alveolar bone so as to be easily removed later, wherein said the abutment has two large flat facets, located on opposite side of the abutment, extended between said circumferential groove and shoulder, and the root of the DIFMA is a m

Abstract: A method for forming a silicone hydrogel contact lens is disclosed, wherein a lens body is formed by curing a mixture of silicone lens matrix, including a filling material, which is water soluble or organic solvent soluble. The lens body, once formed, is processed by water or organic solvent extraction to remove part or whole filling material from the silicone matrix of the lens body. Whereby densely distributed and interconnected pores are formed in the lens body to provide additional wettability required for the contract lens. This method is also applicable of to making other optical medical devices, such as an intraocular lens.

Abstract: Water-soluble chitosan having a low concentration of endotoxin is disclosed. Products containing the water-soluble chitosan are also disclosed. Methods of making and using water-soluble chitosan having a low concentration of endotoxin are further disclosed.

Abstract: Water-soluble chitosan having a low concentration of endotoxin is disclosed. Products containing the water-soluble chitosan are also disclosed. Methods of making and using water-soluble chitosan having a low concentration of endotoxin are further disclosed.