Abstract: A multi-drop, packet energy transfer (PET) receiver configured to be electrically connected to a PET transmission line and an electric load comprising receiver front-end circuitry including an input configured to be electrically connected to the PET transmission line, an output; and at least one switch or at least one diode connected at the output. There is a receiver output control and conditioning circuity with an input connected to the switch/diode, an output to be connected to the electrical load. There is a bootstrap capacitor connected across the input, and a bulk capacitor connected across the output and across the electric load. There is a load controller configured to operate the switch/diode to allow power to flow into the receiver output control and conditioning circuitry during transfer periods and to prevent power to flow into the receiver output circuitry during sample periods.

Abstract: A polygonal cluster includes a plurality of substantially parallel polymeric columns disposed inside an outermost polygonal perimeter of the polygonal cluster and extending along a thickness direction between opposing first and second major surfaces of the polygonal cluster; and a common first material substantially filling regions within the polygonal perimeter between the polymeric columns and across the thickness of the polygonal cluster, such that in a cross-section of the polygonal cluster in a plane substantially orthogonal to the thickness of the cluster, for at least each of a plurality of first polymeric columns in the plurality of polymeric columns disposed adjacent the perimeter of the cluster, the first polymeric column has a pear shape having a wider portion facing the perimeter and a narrower portion facing away from the perimeter.

Abstract: This disclosure provides a method for treating a subject afflicted with tumor, which method comprises administering to the subject an antibody or an antigen-binding portion thereof that specifically binds to a Programmed Death-1 (PD-1) receptor and inhibits PD-1 activity. In some embodiments, the tumor is derived from a non-small cell lung cancer (NSCLC). In some embodiments, the tumor expresses Programmed Death Ligand 1. In some embodiments, the subject carries a wild-type STK11 gene.

Abstract: A diverged beam optical transmitter is provided that includes a laser source configured to emit a light beam, and one or more lenses. The diverged beam optical transmitter also includes a diffuser placed between the laser source and the one or more lenses, and configured to increase an intrinsic divergence of the light beam and to fill some portion of the one or more lenses such that the light beam is eye safe after the one or more lenses.

Abstract: A microwave ablation antenna assembly including a coaxial cable terminating in a radiating section, a first tubular member circumscribing the coaxial cable and spaced therefrom to permit fluid flow therebetween, and a second tubular member circumscribing the first tubular member and spaced therefrom to permit fluid flow therebetween. The microwave ablation antenna assembly further includes a hub configured to receive the coaxial cable, first tubular member, and second tubular member, the hub including a fluid inflow chamber and a fluid outflow chamber and an integrated hub divider and hub cap separating the fluid inflow chamber from the fluid outflow chamber and prohibiting fluid flow between the inflow chamber and outflow chamber except via the spacing between the coaxial cable and the first tubular member and between the first tubular member and the second tubular member.

Abstract: An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein.

Abstract: System and methods include obtaining Wi-Fi network data, over the Internet, associated with a plurality of Wi-Fi networks each Wi-Fi network having one or more access points and each Wi-Fi network being associated with a customer of one or more service providers and obtaining customer data for each customer associated with the plurality of Wi-Fi networks, the customer data including call-ins made by customers; aggregating and filtering the data; analyzing the aggregated and filtered data including correlating the call-ins made by customers to the Wi-Fi network data; predicting customer call-ins based on correlations made between the call-ins made by customers and the Wi-Fi network data; and initiating a customer outreach workflow prior to a predicted customer call-in.

Abstract: An implantable medical lead includes a first defibrillation electrode and a second defibrillation electrode. The implantable medical lead further includes a pacing electrode configured to deliver a pacing pulse that generates an electric field proximate to the pacing electrode. The implantable medical lead further includes a shield disposed over a portion of an outer surface of the pacing electrode and extending laterally away from the pacing electrode. The shield is configured to impede the electric field in a direction from the pacing electrode away from a heart. The implantable medical lead further includes a conductive surface disposed on the shield and electrically coupled to the pacing electrode.

Abstract: A container including a finish, a body, and a base. The finish includes a top sealing surface, threads, and a support flange. The top sealing surface includes only a base layer. The body and the base each include an inner portion made of the base layer, an outer portion made of the base layer, and an oxygen barrier layer between the inner portion and the outer portion.

Abstract: A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and the neck. The shape memory polymer foam has pores that include a first multiplicity of pores having a first pore size and a second multiplicity of pores having a second pore size. The second pore size is larger than said first pore size. The first multiplicity of pores are located in the neck of the aneurysm. The second multiplicity of pores are located in the dome of the aneurysm.

Abstract: A system for lung assist includes a fiber bundle section including a fiber bundle housing defining a fiber bundle compartment therein, and a fiber bundle within the fiber bundle compartment. The fiber bundle housing includes a first interface on a second end of the fiber bundle housing opposite a first end thereof. The system further includes a base section having a housing including a pressurizing section including a pressurizing compartment and an interface section. The interface section includes an extending section which extends from a lateral end of the pressurizing section. The interface section includes a second interface formed on the extending section, which includes a releasable seal member configured to form a releasable sealing connection with the first interface of the fiber bundle section. The base section housing and the fiber bundle housing are separate elements connected by a releasable, sealing connection between the first and second interfaces.

Abstract: Illuminations systems that separate different colors into laterally displaced beams may be used to direct different color image content into an eyepiece for displaying images in the eye. Such an eyepiece may be used, for example, for an augmented reality head mounted display. Illumination systems may be provided that utilize one or more waveguides to direct light from a light source towards a spatial light modulator. Light from the spatial light modulator may be directed towards an eyepiece. Some aspects of the invention provide for light of different colors to be outcoupled at different angles from the one or more waveguides and directed along different beam paths.

Abstract: A packet energy transfer (PET) receiver comprising receiver front-end circuitry including an input, an output, and at least one switch connected at the output. There is receiver output control and conditioning circuity including an input and an output to be connected to an electrical load. There is a synchronizer circuit to close the switch to allow power to flow into the receiver output control and conditioning circuitry during each of the first plurality of transfer periods of the transmitter and to open the switch to prevent power to flow into the receiver output circuitry during a first plurality of sample periods. There is a load controller that disables the synchronizer circuit and operates the switch to close it and allow power to flow into the receiver output control and conditioning circuitry during subsequent transfer periods and to open the switch to prevent power to flow during a subsequent sample periods.

Abstract: Adsorbent material for use in pressure swing adsorption (PSA) related processing can provide improved purification processing with reduced temperature differentials between adsorption and desorption processing of the bed of adsorbent material. Embodiments can be configured so that adsorbent material has occluded micropores or macropores. The occlusion of the micropores or macropores can be up to 42% of the micropores the adsorbent material in some embodiments. At least one metal acetate can be utilized for the occlusion of the micropores or macropores. Utilization of the adsorbent material having occluded micropores or macropores was surprisingly found to increase the yield for purification of a product gas in spite of the occlusion of the micropores or macropores.

Abstract: System and methods include obtaining data, over the Internet, associated with a plurality of Wi-Fi networks each Wi-Fi network having one or more access points and each Wi-Fi network being associated with a customer of one or more service providers; aggregating and filtering the data; analyzing the aggregated and filtered data for Wi-Fi metric based alarms, each Wi-Fi metric based alarm being associated with detection of one of an offline Wi-Fi network of the plurality of Wi-Fi networks, an offline node of the Wi-Fi network, instability of the Wi-Fi network, congestion in the Wi-Fi network, and interference in the Wi-Fi network; determining the Wi-Fi metric based alarms based on the analyzing; and performing one or more actions based on the determined Wi-Fi metric based alarms.

Abstract: An electrolyte enhanced spirit is disclosed. The electrolyte enhanced spirit comprises a spirit and at least two electrolyte salts at a concentration of at least 0.02% w/v. The spirit in some embodiments includes vodka, rum, bourbon, whiskey, gin and distilled liquors. The electrolyte salts include NaCl, NaHCO3, KCl, KHCO3, K3PO4. The electrolyte enhanced spirit has a pH of 9.3 to 9.7, preferably 9.5. The electrolyte enhanced spirit may also include an additive to control the pH. The additive for controlling the pH of the spirit is selected from at least one of citric acid, an amino acid, ascorbic acid, folic acid, malic acid, phosphoric acid, phosphorous acid, carbonic acid, fumaric acid, tartaric acid, tannic acid, benzoic acid, lactic acid, and acetic acid.

Abstract: Methods, systems, and apparatus are described providing networking engines. Specifically, the present specification relates to a method for implementing software containers implementing network engines that may be configured to act in a zero-knowledge environment. In such implementations, all information pertaining to the network engine associated with a user that is stored in the container is solely that of a user unless explicitly shared by the user. In some implementations, the containers may be configured to participate in a publish-and-subscribe network in order to share information. In addition, the containers may be provisioned with controls so that global operators may comply with local privacy rules.

Abstract: Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS G12D and/or KRAS G12C inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.

Abstract: An interference reduction device is provided. The interference reduction device may include a magnetic shield positioned in proximity of a magnetic field. The magnetic shield is configured to reduce interference on the magnetic field along the direction of the magnetic field. The magnetic shield may include a cutout approximately parallel to the direction of the magnetic field, the cutout is configured to reduce a distortion caused by the magnetic shield on the magnetic field.

Abstract: Among other things, there are disclosed embodiments of belts or bands that can be used in treatments for tricuspid valve regurgitation. In some embodiments, such belts may be heat-set in a particular configuration to effectively decrease tricuspid annulus when deployed around the atrioventricular groove. Embodiments include one or more tensioning sutures for applying cinching or tightening to belts when deployed, and structure for effectively distributing force during such tightening. Embodiments of tensioning members, protective members, and devices and methods for open-surgical placement (e.g. around a heart for annuloplasty) are also disclosed.