Abstract: IL-7R??c binding compounds and pharmaceutical compositions comprising the IL-7R??c binding compounds are disclosed. IL-7R??c bonding compounds can act as IL-7R agonists and are useful in treating cancer, viral diseases, autoimmune diseases, and inflammatory diseases.

Abstract: The use of IL-7R??c agonist peptides in cell manufacturing is disclosed. The IL-7R??c agonist peptides can facilitate the selective growth of immune cell populations. Culture media comprising the IL-7R??c agonist peptides, methods of expanding a target immune cell population, and methods of manufacturing a target immune cell population are disclosed. The enriched immune cell populations can be used in immunotherapy.

Abstract: The use of IL-2R??c agonist peptides in cell manufacturing is disclosed. The IL-2R??c agonist peptides can facilitate the selective growth of immune cell populations. Culture media comprising the IL-2R??c agonist peptides, methods of expanding a target immune cell population, and methods of manufacturing a target immune cell population are disclosed. The enriched immune cell populations can be used in immunotherapy.

Abstract: A system for heat-shrinking a film onto an open-topped container is provided, including at least one reflective cup having a reflective interior surface, and at least one radiant energy source. The reflective cup and the radiant energy source may be rotationally mounted. The interior surface of the reflective cup has at least an elliptical portion and a parabolic portion.

Abstract: A system for heat-shrinking a film onto an open-topped container is provided, including at least one reflective cup having a reflective interior surface, and at least one radiant energy source. The reflective cup and the radiant energy source may be rotationally mounted. The interior surface of the reflective cup has as least an elliptical portion and a parabolic portion.

Abstract: A radiant energy device for shrinking a thin film onto an open top of a container, the radiant energy device comprising: a source of power, to provide power to the radiant energy device; a plurality of fixed energy-emitting units, each of the units when energized being configured to emit radiant energy towards the shrinking film on said open top of the container; and a switching means, operatively connected between the source of power and each of the energy-emitting units, to independently activate at least two groups of the energy-emitting units; wherein, a first group of the energy-emitting units partially shrinks the thin film onto the container, and a second group finishes the shrinking.

Abstract: A modular rotational assembly is providing having an upper plate and at least one radiant energy source. The modular rotational assembly may have at least two radiant energy sources. The modular rotational assembly may also include at least one reflective cup, wherein the radiant energy source is located within the reflective cup. The modular rotational assembly may also include a web cutter. The web cutter may include at least one cutting member and at least one wheel assembly.

Abstract: A container centering device is provided including an entry plate having an opening and a container positioning means, wherein the container positioning means is capable of positioning a container in the entry plate opening. In addition, the container positioning means is capable of positioning a first container and at least a second container in the entry plate opening, wherein the first and second containers have different brim diameters.

Abstract: A container positioning device is provided including an lower plate having an opening and a container positioning means, wherein the container positioning means is capable of positioning a container in the lower plate opening. In addition, the container positioning means is capable of positioning a first container and at least a second container in the lower plate opening, wherein the first and second containers have different brim diameters.

Abstract: A web cutter is provided comprising an at least one wheel assembly. The wheel assembly includes a wheel housing and at least two wheel members. A cutting member is disposed between the wheel members, wherein the wheel assembly has a first position wherein the cutting member does not extend below the wheel members and a second position wherein the cutting member extends below the wheel members. The web cutter may include an upper plate having a receiving hole, and the wheel assembly may include a post that is in slideable communication with the upper plate receiving hole. The cutting member may be in fixed communication with the upper plate.

Abstract: A system for heat-shrinking a film onto an open-topped container is provided, including at least one reflective cup having a reflective interior surface, and at least one radiant energy source. The reflective cup and the radiant energy source may be rotationally mounted. The interior surface of the reflective cup has as least an elliptical portion and a parabolic portion.

Abstract: A radiant energy device for shrinking a thin film onto an open top of a container, the radiant energy device comprising: a source of power, to provide power to the radiant energy device; a plurality of fixed energy-emitting units, each of the units when energized being configured to emit radiant energy towards the shrinking film on said open top of the container; and a switching means, operatively connected between the source of power and each of the energy-emitting units, to independently activate at least two groups of the energy-emitting units; wherein, a first group of the energy-emitting units partially shrinks the thin film onto the container, and a second group finishes the shrinking.

Abstract: A device for heat shrinking thin film onto open-topped containers to form spill-resistant covers is shown. A radiant energy source is intermittently energized in association with timers to direct radiant energy towards the thin film. An energy absorbing body is associated with the thin film to absorb energy and create heat adjacent to the film which in turn causes the thin film to shrink. The energy absorbing body can be the adaptation of the thin film to be opaque to the radiant energy by either being coated with an energy absorbing coating such as printing, or being made partially opaque by means of tinting. The container can also be adapted to absorb energy by including a darkened band adjacent the upper edge of the rim. The device can also interpose an energy absorbing body, such as a darkened aluminum screen adjacent to the film to be heated to cause the thin film to shrink.

Abstract: A packaging film which shrinks to form at least part of a package when exposed to heat. The packaging film includes a thin film substrate that contracts or shrinks when heated and which is substantially transparent to radiant energy. The film also includes a susceptor material carried by the film that is sufficiently opaque to radiant energy to absorb and transfer to the substrate enough heat energy to cause the substrate to shrink, when the film is exposed to a source of radiant energy. In one embodiment the packaging film takes the form of lids of beverage containers.

Abstract: A packaging film which shrinks to form at least part of a package when exposed to heat. The packaging film includes a thin film substrate that contracts or shrinks when heated and which is substantially transparent to radiant energy. The film also includes a susceptor material carried by the film that is sufficiently opaque to radiant energy to absorb and transfer to the substrate enough heat energy to cause the substrate to shrink, when the film is exposed to a source of radiant energy. In one embodiment the packaging film takes the form of lids of beverage containers.

Abstract: A device for heat shrinking thin film onto open-topped containers to form spill-resistant covers is shown. A radiant energy source is intermittently energized in association with timers to direct radiant energy towards the thin film. An energy absorbing body is associated with the thin film to absorb energy and create heat adjacent to the film which in turn causes the thin film to shrink. The energy absorbing body can be the adaptation of the thin film to be opaque to the radiant energy by either being coated with an energy absorbing coating such as printing, or being made partially opaque by means of tinting. The container can also be adapted to absorb energy by including a darkened band adjacent the upper edge of the rim. The device can also interpose an energy absorbing body, such as a darkened aluminum screen adjacent to the film to be heated to cause the thin film to shrink.

Abstract: A device for heat shrinking thin film onto open-topped containers to form spill-resistant covers is shown. A radiant energy source is intermittently energized in association with timers to direct radiant energy towards the thin film. An energy absorbing body is associated with the thin film to absorb energy and create heat adjacent to the film which in turn causes the thin film to shrink. The energy absorbing body can be the adaptation of the thin film to be opaque to the radiant energy by either being coated with an energy absorbing coating such as printing, or being made partially opaque by means of tinting. The container can also be adapted to absorb energy by including a darkened band adjacent the upper edge of the rim. The device can also interpose an energy absorbing body, such as a darkened aluminum screen adjacent to the film to be heated to cause the thin film to shrink.

Abstract: There is provided an apparatus for allowing a paper tape to be unwound from a first roll by a printing unit, and for simultaneously rewinding the paper tape on a second roll. Each roll includes a hollow cylindrical core. The apparatus includes a low friction cylindrical axle means for positioning within the hollow core of the second roll, and alignment means for maintaining the axle means such that its axis remains parallel with the axis of the second roll, and for keeping the two rolls laterally aligned. Retention means are also provided for keeping the two rolls together, the retention means preferably including an elastic cord member adapted to pass in a closed loop through the hollow core of the first roll and through a central opening in the axle means positioned in the hollow core of the second roll.