Patents by Inventor William J. Catalona

William J. Catalona has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS
    Publication number: 20140134658
    Abstract: The disclosure provides for methods to determine prognosis, aggressiveness, and progression of prostate cancer with the ability to differentiate between aggressive and non-aggressive prostate cancer. The method utilizes the differential enzymatic activity in patient samples, for example of enzymatically active prostate specific antigen (PSA) activity, in order to determine the aggressiveness and prognosis of prostate cancer, and monitor the progression of prostate cancer therapy. The invention also encompasses assay platforms (e.g., optical or electrochemical) that specifically detect PSA-triggered peptide cleavage events.
    Type: Application
    Filed: September 20, 2013
    Publication date: May 15, 2014
    Applicants: NOTRHWESTERN UNIVERSITY, AN ILLINOIS NOT FOR PROFIT CORPORATION, OHMX CORPORATION
    Inventors: Michael J. Ahrens, Byron Anderson, Paul A. Bertin, William J. Catalona, Dimitra Georganopoulou
  • Electrochemical assay for the detection of enzymatically active PSA
    Publication number: 20120034638
    Abstract: The present invention is directed to the diagnosis of cancer associated with enzymatically active PSA in samples.
    Type: Application
    Filed: May 23, 2011
    Publication date: February 9, 2012
    Inventors: Michael Ahrens, Byron Anderson, Paul A. Bertin, Dimitra Georganopoulou, William J. Catalona