Patents by Inventor William J. DeLorbe

William J. DeLorbe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular cloning of RNA using RNA ligase and synthetic oligonucleotides
    Patent number: 4661450
    Abstract: Methods and compositions for the insertion and molecular cloning of RNA in DNA cloning vectors are described. RNA molecules to be cloned are modified by the ligation of oligonucleotide linkers onto the termini of the RNA molecule using T4 RNA ligase. Such linkers may be composed of DNA, RNA, or mixtures of each and facilitate the insertion and ligation of the RNA species into a DNA cloning vector. The resulting recombinant vectors are used to transform host cells which provide for the generation of multiple DNA copies of the RNA molecule.
    Type: Grant
    Filed: May 3, 1983
    Date of Patent: April 28, 1987
    Assignee: Molecular Genetics Research and Development Limited Partnership
    Inventors: Tomas Kempe, Anthony F. Purchio, Marc S. Collett, William J. DeLorbe