Abstract: An endoluminal prosthesis may include a tubular main body and a branch. The main body may include proximal and distal end openings, a lumen, a sidewall, and a fenestration in the sidewall. The branch may include a tubular retrograde branch segment, a tubular antegrade branch segment, and a tubular branch junction. The retrograde branch segment may include an inlet opening fluidly coupled to the fenestration of the main body and an outlet opening fluidly coupled to the branch junction and positioned longitudinally between the proximal end opening and the fenestration of the main body. The antegrade branch segment may include an inlet opening fluidly coupled to the branch junction and an outlet opening positioned longitudinally distal of the inlet opening of the antegrade branch segment. The retrograde branch segment and the antegrade branch segment may be in fluid communication with one another through the branch junction.

Abstract: In one example, this disclosure is directed to a method for intravascular implantation of an implantable medical device comprising positioning a distal end of an elongated outer sheath forming an inner lumen adjacent a target site within a vasculature of a patient, and partially deploying an implantable medical device from the distal opening, wherein the implantable medical device includes an expandable fixation element. A portion of the expandable fixation element assumes an expanded position when the implantable medical device is partially deployed from the distal opening. The method including advancing the distal end of the outer sheath within the vasculature with the implantable medical device partially deployed from the distal opening, and monitoring at least one of the vasculature and the portion of the expandable fixation element for deflection to determine when the size of the portion of the expandable fixation element corresponds to the size of the vasculature.

Abstract: Among other things, there is shown a system for filling vials with fluid that maintains a localized sterile zone around the filling location. In particular embodiments, the sterile zone is provided by a manifold having an internal space to which clean air is supplied. One or more filling assemblies are attached to the manifold. Vials enter the sterile zone and are filled within it. Additional structure, such as coverings for vials, are disclosed to assist in maintaining sterility.

Abstract: An endoluminal prosthesis that includes a support structure having a plurality of struts and an anchor that is attachable to the support structure. The anchor includes an anchor body and one or more barbs extending outwardly from the anchor body. The anchor body includes a cannula having a first end, a second end, and a middle section. The middle section includes a plurality of open portions arranged in a plurality of arrays around the anchor body.

Abstract: The present embodiments provide systems and methods for deploying at least a portion of a stent. In one embodiment, the system comprises a cannula having an outer surface, and an auger having a plurality of turns coupled to the outer surface of the cannula. A stent has a portion dimensioned to be disposed within a valley of the auger. Rotation of the cannula and the auger advances the portion of the stent in a predetermined longitudinal direction.

Abstract: An endoluminal prosthesis that includes a support structure having a plurality of struts and an anchor that is attachable to the support structure. The anchor includes an anchor body and one or more barbs extending outwardly from the anchor body. The anchor body includes a cannula having a first end, a second end, and a middle section. The middle section includes a plurality of open portions arranged in a plurality of arrays around the anchor body.

Abstract: A stent-graft comprises a substantially tubular graft material, and a stent coupled to the graft material. The stent has proximal and distal ends and further has compressed and deployed states. The proximal end is disposed proximally beyond a proximal edge of the graft material, and the distal end has at least one portion overlapping with the proximal edge of the graft material. In one example, the stent comprises at least one distal apex having a bifurcation extending into first and second leg regions. A distal end of the first leg region is positioned to overlap the graft material at a location circumferentially spaced apart from a location at which a distal end of the second leg region overlaps the graft material in the deployed state.

Abstract: A filling and sealing system is provided for efficiently filling a series of individual vials with therapeutic liquids. In particular embodiments, the system includes a filling zone or station, a sealing zone or station, an unloading zone or station, and electronic controls.

Abstract: The present embodiments provide systems and methods for deploying at least a portion of a stent. In one embodiment, the system comprises a cannula having an outer surface, and an auger having a plurality of turns coupled to the outer surface of the cannula. A stent has a portion dimensioned to be disposed within a valley of the auger. Rotation of the cannula and the auger advances the portion of the stent in a predetermined longitudinal direction.

Abstract: Disclosed are embodiments of devices and methods for imaging the inside of a body part, such as a blood vessel. In particular embodiments, a catheter has a chamber within which is a transducer. A wire guide channel extends throughout the length of the catheter. The transducer is rotatable about the wire guide channel and the transducer is driven by a cable or other device that is connected to a motor which is located outside the catheter. In one form, a torque cable connects the transducer to the motor. In other embodiments, a pusher piece having a plurality of lumens is positioned in the catheter. Each of the lumens is sized to receive a cable, wire, and/or flushing fluid. The lumens maintain the orientation and separation of the cables, wires, and/or to flushing fluid.

Abstract: Devices and methods for obtaining a real-time, three-dimensional image of a body part, particularly a blood vessel. A catheter has a chamber in its tip. The chamber contains an ultrasound transducer and reflector which generally face each other and rotate about a common axis. The transducer element on the transducer and the reflective face on the reflector are both tilted off-axis. The difference in angular velocity generally creates a phase shift between the transducer and the reflective face. The phase shift allows the transducer and the reflective face to actively scan a three-dimensional volume that is generally bounded interiorly by a hyperboloid and exteriorly by the effective range of the ultrasound beam. The transducer and reflector may rotate at constant speeds or nonconstant speeds as well in the same direction or in opposite directions.

Abstract: A prosthesis delivery device comprises a proximal end and a distal end, a prosthesis retention section at the proximal end, and a prosthesis retained on the prosthesis retention section. The prosthesis has a proximal end releasably attached at the prosthesis retention section and a distal end releasably attached at the prosthesis retention section. A sheath is slidably disposed over the prosthesis. A delivery handle near the distal end the delivery device comprises a rotatable inner cannula having a cannula lumen and cannula handle. The cannula handle is rotatable with the inner cannula. Further, a positioner handle is releasably engaged with the cannula handle. Rotation of the inner cannula releases the proximal end of the prosthesis from the delivery device and withdrawal of the sheath from over the prosthesis releases the distal end of the prosthesis from the delivery device.

Abstract: A device for internal ultrasound procedures includes a motor which rotates a drive shaft and an ultrasound transducer. A gearing assembly provides reciprocating rotational motion from a unidirectional motor. A cam assembly provides reciprocating pivotal motion to the transducer. Conductors can attach to the transducer and extend through the drive shaft.

Abstract: A prosthesis delivery device comprises a proximal end and a distal end, a prosthesis retention section at the proximal end, and a prosthesis retained on the prosthesis retention section. The prosthesis has a proximal end releasably attached at the prosthesis retention section and a distal end releasably attached at the prosthesis retention section. A sheath is slidably disposed over the prosthesis. A delivery handle near the distal end the delivery device comprises a rotatable inner cannula having a cannula lumen and cannula handle. The cannula handle is rotatable with the inner cannula. Further, a positioner handle is releasably engaged with the cannula handle. Rotation of the inner cannula releases the proximal end of the prosthesis from the delivery device and withdrawal of the sheath from over the prosthesis releases the distal end of the prosthesis from the delivery device.

Abstract: The present embodiments provide systems and methods for deploying at least a portion of a stent. In one embodiment, the system comprises a cannula having an outer surface, and a coiled member having proximal and distal ends and a plurality of turns disposed therebetween. At least a portion of the coiled member is secured to the outer surface of the cannula. A stent is releasably secured to a portion of the coiled member. A protective cage may encircle the coiled member.

Abstract: A prosthesis delivery device comprises a cannula having an expandable positioning device disposed at the proximal end thereof. A prosthesis is retained on the cannula distal of the expandable device. Expansion of the expandable device retains and centers the delivery device and the prosthesis carried thereon in the vessel and allows repositioning of the prosthesis without contacting the proximal end of the prosthesis with the vessel walls prior to deployment.

Abstract: Disclosed are embodiments of devices and methods for imaging the inside of a body part, such as a blood vessel. In particular embodiments, a catheter has a chamber within which is a transducer mounted to a pivot mechanism, a motor for turning the transducer, and a coil for providing a pivot force to the transducer. A magnet is attached to the transducer and is receptive of a torque applied by a magnetic field produced by energizing of the coil.

Abstract: A system for treating a body vessel may include a delivery device and a prosthesis retained on the delivery device. The prosthesis may include a main body and first and second legs each extending from the main body. The main body may include a lumen, and the first leg may include a lumen in fluid communication with the lumen of the main body. The second leg may include a tubular graft body and a stent attached to the graft body. The prosthesis may have a predeployment configuration in which the graft body of the second leg is inverted into and positioned within the lumen of the first leg, and the stent is positioned outside of the inverted graft body. The prosthesis may have a deployed configuration in which the second leg extends outward from the main body, and the stent is positioned within a lumen of the graft body.

Abstract: Described in one aspect is a multi-cell or multi-chambered container for sealing various materials such as therapeutic or diagnostic agents, animal or human tissue, tissue samples, specimens, blood, genetic material, or any other material. The container includes seals formed by folding the wall of the elongate body transverse to the interior of the elongate body and maintaining the folded wall portions adjacent one another or joining them together. In another aspect, the container disclosed may be made according to a method involving creating multiple seals at various locations along the elongate body thus creating sealed voids or cells between the seals within the elongate body.

Abstract: Described are embodiments of devices and methods for imaging a body conduit, such as a blood vessel. In particular embodiments, the catheter has a chamber within which is a transducer mounted to a pivot mechanism. A coil provides a pivot force to the transducer. A magnet is attached to the transducer and is receptive of a torque applied by a magnetic field produced by energizing of the coil. A driving mechanism receives an impact from the pivot member and causes the pivot mechanism to rotate about a rotation axis.