Patents by Inventor William J. Henzel

William J. Henzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel FIZZ proteins
    Publication number: 20040018980
    Abstract: The present invention is directed to novel polypeptides, designated FIZZ, which are secreted low molecular weight molecules showing no significant sequence homology to any known protein, and nucleic acid sequences encoding such proteins. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptide of the present invention fused to heterologous polypeptide sequences, and antibodies which bind to the polypeptides of the present invention. Methods of using FIZZ polypeptides to treat various neurotrophin-related conditions are further provided.
    Type: Application
    Filed: June 13, 2003
    Publication date: January 29, 2004
    Applicant: Genentech, Inc.
    Inventors: Austin L. Gurney, Caroline Hebert, William J. Henzel, Rhona Kabakoff, David L. Shelton, Daniel B. Tumas
  • Apaf-1 an activator of caspase-3
    Patent number: 6291643
    Abstract: Novel polypeptides, designated Apaf-1, which are capable of modulating apoptosis are provided. Compositions including Apaf-1 chimeras, nucleic acid encoding Apaf-1, and antibodies to Apaf-1 are also provided.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: September 18, 2001
    Assignees: Board of Reports, The University of Texas System, Genentech, Inc.
    Inventors: Hua Zou, William J. Henzel, Xiaodong Wang