Abstract: A pump system selectably controls the temperature, flow rate, flow volume, and flow pressure of a fluid being infused into a patient's body. The pump system includes a cartridge and components that removably connect with a pump housing and corresponding components, providing simple attachment of the cartridge to the pump housing. The pump housing includes a pressure sensor, a bubble detector, and a temperature sensor on a first side of the pump housing, and an engaging actuator and a central controller. The cartridge includes on a first side a heat exchanger, a pressure receptor correspondingly aligned with the pressure sensor, and a detector interface correspondingly aligned with the bubble detector and temperature sensor. Upon aligning the cartridge with the pump housing and actuating the engaging actuator, the pressure receptor communicates with the pressure sensor and the detector interface aligns with the bubble detector and temperature sensor.

Abstract: A microchamber structure (100) comprising a base layer (120), a lid layer (130), and at least one microchamber (140) having a cross-sectional shape with a depth (d) of less than 1000 microns and a width (w) of less than 1000 microns. The base layer (120) includes a depression (122) and the lid layer (104) includes a projection (132) positioned within the depression (122) to together define the cross-sectional shape of the microchamber (140).

Abstract: A pump system selectably controls the temperature, flow rate, flow volume, and flow pressure of a fluid being infused into a patient's body. The pump system includes a cartridge and components that removably connect with a pump housing and corresponding components, providing simple attachment of the cartridge to the pump housing. The pump housing includes a pressure sensor, a bubble detector, and a temperature sensor on a first side of the pump housing, and an engaging actuator and a central controller. The cartridge includes on a first side a heat exchanger, a pressure receptor correspondingly aligned with the pressure sensor, and a detector interface correspondingly aligned with the bubble detector and temperature sensor. Upon aligning the cartridge with the pump housing and actuating the engaging actuator, the pressure receptor communicates with the pressure sensor and the detector interface aligns with the bubble detector and temperature sensor.

Abstract: A sheet (20) for use in microfluidic, microelectronic, micromechanical, and/or microoptical applications requiring through-flow, through-conductivity, through-transmission, and/or other through patterns. The sheet (20) includes micro-sized architecture including at least one via (22) extending through the thickness of the layer of thermoplastic material. The via-defining walls in the thermoplastic layer are formed by the thermoplastic material flowing around a projection and then solidifying around the projection.

Abstract: A microchamber structure (100) comprising a base layer (120), a lid layer (130), and at least one microchamber (140) having a cross-sectional shape with a depth (d) of less than 1000 microns and a width (w) of less than 1000 microns. The base layer (120) includes a depression (122) and the lid layer (104) includes a projection (132) positioned within the depression (122) to together define the cross-sectional shape of the microchamber (140).

Abstract: A fluid delivery system includes a valve device, a pump system operable to pressurize a fluid and a patient interface. The valve device includes a sealing element and defines at least a first outlet and a second outlet. The first outlet includes a first member of a connector. The pump system is operably associated with the second outlet of the valve device. The patient interface includes a second member of the connector and a tube in fluid connection with the second member. The second member of the connector is adapted to be removably connected to the first member of the connector. The first member preferably includes a resilient septum, and the second member preferably includes a penetrating member.

Abstract: An aseptic connector comprises a first member and a second member. The first member preferably includes a resilient septum, and the second member preferably includes a penetrating member. Preferably, the septum is formed from an elastomeric material such as a silicone elastomer. The penetrating member preferably includes an extending penetrating element to penetrate the resilient septum. The aseptic connector further comprises a resilient sealing element that contacts the penetrating member and one of an inner wall of the first member and an inner wall of the second member to create a seal between the penetrating member and one of the inner wall of the first member and the inner wall of the second member. The seal created is suitable to withstand relatively high pressures (for example, those experienced during the injection of contrast media in CT procedures). A fluid delivery system comprising at least a first aseptic connector as described above is also provided.

Abstract: An aseptic connector comprises a first member and a second member. The first member preferably includes a resilient septum, and the second member preferably includes a penetrating member. Preferably, the septum is formed from an elastomeric material such as a silicone elastomer. The penetrating member preferably includes an extending penetrating element to penetrate the resilient septum. The aseptic connector further comprises a resilient sealing element that contacts the penetrating member and one of an inner wall of the first member and an inner wall of the second member to create a seal between the penetrating member and one of the inner wall of the first member and the inner wall of the second member. The seal created is suitable to withstand relatively high pressures (for example, those experienced during the injection of contrast media in CT procedures). A fluid delivery system comprising at least a first aseptic connector as described above is also provided.