Patents by Inventor William J. Littlehales

William J. Littlehales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4859419
    Abstract: Apparatus for immunoassay of multiple samples of biological fluids (e.g., AIDS antibodies), the apparatus being capable of mounting for rocking during incubation. A frame receives plural test vessels so that the vessels are interconnected for circulation through all the vessels of buffers, de-ionized water and air and for discharge of waste. Each vessel is transparent and contains nitrocellulose test paper impregnated with antigens to the antibodies. Valved ports in each vessel accept sequential insertion of the biological fluids, an enzyme conjugate and color developer. Color changes in the individual test papers are observed through the transparent vessels and identify presence of antibodies in the samples.
    Type: Grant
    Filed: February 27, 1987
    Date of Patent: August 22, 1989
    Assignee: American Bionetics, Inc.
    Inventors: Martin E. Marks, William J. Littlehales, Chu-An Chang
  • Patent number: 4840714
    Abstract: An apparatus especially suitable for transferring a particular specimen from a polyacrylamide electrophoresis or like gel onto a support sheet by means of electroblotting is disclosed herein along with its method of operation. This apparatus utilizes a pair of plate-shaped electrode assemblies, each of which in the disclosed embodiment is a multilayered assembly including an electrode layer of electrically conductive material and a layer of thermally conductive material which serves as a heat sink. These electrode assemblies are adjustably supported in spaced-apart but confronting relationship to one another with the gel and support sheet sandwiched therebetween. At the same time, the electrode layers are connected to a source of power for producing an electric field across the gel and support sheet in order to transfer the specimen from the gel to the sheet by means of electroblotting.
    Type: Grant
    Filed: May 13, 1987
    Date of Patent: June 20, 1989
    Assignee: American Bionetics, Inc.
    Inventor: William J. Littlehales
  • Patent number: 4818701
    Abstract: An apparatus for transferring biological specimens such as nucleic acid samples from a gel such as an agarose gel to a cooperating transfer membrane by means of a liquid transfer process is disclosed herein along with its method of use. The arrangement includes means for supporting a given gel on top of a given transfer membrane and a trough located below both. An arrangement is provided for defining a reservoir for containing a transfer liquid on top of the gel and means are also provided for causing transfer liquid contained within the reservoir to pass through the gel and transfer medium and into the trough, so as to effect a transfer of particular biological specimens carried by the gel onto the membrane.
    Type: Grant
    Filed: May 13, 1987
    Date of Patent: April 4, 1989
    Assignee: American Bionetics, Inc.
    Inventor: William J. Littlehales