Abstract: A fishing pole tip-up system for signaling to a fisherman that a fish bite has occurred using a conventional fishing rod. The inventive device includes a shaft having a pointed lower end, a stability member attached to the shaft near the lower end, a rod support pivotally attached to the upper end of the shaft, an indicator structure attached to the upper end of the shaft, and a catch member pivotally attached to the shaft. The lower end of the shaft is designed to penetrate all types of ground surfaces such as sand, gravel or dirt. The rod support comprises a first claw and a second claw for releasably retaining a conventional fishing rod in a relatively horizontal position. The indicator structure comprises a flex spring attached to the upper end of the shaft, and a pole with a flag attached to the flex spring opposite of the shaft. The catch member includes a slot, wherein the slot releasably captures the pole of the indicator structure.

Abstract: A positive displacement pipette tip in which a one-piece piston having a tapered end slides within a capillary tube having a matching taper. The capillary tube includes a collar with a snap ring for attachment to the body of a pipette. The piston includes a two-prong fork-like coupling for attachment to the plunger of the pipette. Attachment of the pipette tip can be made without physical handling, and ejection is achieved by an over extension of the pipette plunger. The pipette tip has a precision outlet orifice for drawing and dispensing liquid, and is suitable for DNA research such as that involving polymerized chain reactions.