Abstract: An external support that routes the tubing of a reversing valve in such a manner that connection tubes extend from one end of the device and the treatment device tubes extend from the opposite end. The external support may provide guides that hold the tubing extending from the supported flat rotary switch type of valve so as to keep them from being pinch or kinked thereby ensuring free flow of blood.

Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

Abstract: Embodiments include a consumable medical device comprises a rigid cartridge to which a film is adhered to form a fluid channel and a damper chamber. A portion of the film forming the damper chamber has a wave-like shape adapted to roll onto a tip of a damper. The damper has a plunger to minimize peristaltic pressure in the channel. The cartridge may include conductivity measurement channels. Crosstalk may be minimized by using different frequencies or time division for reading the channels. A stable dialysate concentrate containing sodium lactate may be used or generated with the system. The concentrate may be formed to higher concentration than feasible with a single component concentrate by forming two containers of concentrate, each containing a fraction of a total quantity of sodium lactate required for a predefined number of dialysis.

Abstract: A pressure measurement pod for use in blood circuits includes a pressure sensing pod defining a chamber and having a rigid wall portion and an integral flexible wall portion forming a flexible, moveable, fluid-impermeable diaphragm with a first major side thereof facing an interior of the chamber and a second major side opposite the first major side. The second major side faces outwardly away from the chamber, and the pod has ports on sides of the chamber. The internal surfaces of the chamber and ports are shaped such that any contour following the internal surfaces to the outside of one of the ports traces only surfaces characterized by positive or neutral draft angles such that invasive mold portions may be withdrawn through the ports thereby permitting the pressure measurement pod to be molded in a single shot molding process.

Abstract: According to embodiments, priming systems, methods, and devices are disclosed which allow medical treatment devices which pump fluid to be primed with minimal operator intervention and a high level of convenience. A blood circuit with a filter fitted with one or more air vents on a non-blood compartment is attached to a treatment system and priming fluid pumped slowly through the blood circuit in a loop. The source of fluid may be elevated, or the pumping may generate pressure, such that priming fluid is forced through the membrane of the filter and out the air vent(s). In embodiments, the vents are hydrophobic which prevent fluid from being ejected, so the priming system can run without intervention.

Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

Abstract: A pressure measurement pod for blood circuits can include a flexible, moveable, fluid-impermeable diaphragm and can be formed via either a one-shot or a two-shot molding process. A method of manufacturing a pressure measuring device can include providing first and second major mold parts having recesses defining major parts of a housing, and inserting pins in the first and second major mold parts, the pins being shaped to define a flow channel of a molded pressure measuring pod. One of the pins may have a major face that defines an internal surface of a diaphragm. The method may further include closing the first and second major mold parts with the pins therebetween and injection molding a pressure pod housing. Finally, the pressure pod is removed from the mold parts and the pins are withdrawn from the flow channel.

Abstract: Releasable tubing pinch clamps of a generally U-shaped configuration are described. The embodiments include ones that prevent cross-clamping of the tube by various interlocking features on riser portions of the clamp. Methods and molds for making the pinch clamps are also described. For example, a pinch clamp can have a strip that curves so that its ends can be brought together by manually squeezing the strip at its end, which oppose each other as a result of the strip curve. The strip ends have locking edges or surfaces that cause the strip ends to interferingly engage with each other and lock together. The strip also has opposing pinch projections that can pinch a tube.

Abstract: A tubular medical fluid flow set comprises a pressure sensing chamber connected in flow-through relation to fluid flow tubing of the set. The pressure sensing chamber defines a movable, flexible, impermeable diaphragm dividing the chamber into two separate compartments. The fluid flow tubing communicates with one of the compartments and is isolated from the other of the compartments. A port is carried on the chamber, the port having a seal therein, and communicating with the other of the compartments. Thus, the other of the compartments is hermetically sealed until the port is opened for connection with a pressure measuring device, to keep the flexible diaphragm in a desired, initial position prior to opening of the seal.

Abstract: According to embodiments, priming systems, methods, and devices are disclosed which allow medical treatment devices which pump fluid to be primed with minimal operator intervention and a high level of convenience. A blood circuit with a filter fitted with one or more air vents on a non-blood compartment is attached to a treatment system and priming fluid pumped slowly through the blood circuit in a loop. The source of fluid may be elevated, or the pumping may generate pressure, such that priming fluid is forced through the membrane of the filter and out the air vent(s). In embodiments, the vents are hydrophobic which prevent fluid from being ejected, so the priming system can run without intervention.

Abstract: A tubular medical fluid flow set comprises a pressure sensing chamber connected in flow-through relation to fluid flow tubing of the set. The pressure sensing chamber defines a movable, flexible, impermeable diaphragm dividing the chamber into two separate compartments. The fluid flow tubing communicates with one of the compartments and is isolated from the other of the compartments. A port is carried on the chamber, the port having a seal therein, and communicating with the other of the compartments. Thus, the other of the compartments is hermetically sealed until the port is opened for connection with a pressure measuring device, to keep the flexible diaphragm in a desired, initial position prior to opening of the seal.

Abstract: According to embodiments, priming systems, methods, and devices are disclosed which allow medical treatment devices which pump fluid to be primed with minimal operator intervention and a high level of convenience. A blood circuit with a filter fitted with one or more air vents on a non-blood compartment is attached to a treatment system and priming fluid pumped slowly through the blood circuit in a loop. The source of fluid may be elevated, or the pumping may generate pressure, such that priming fluid is forced through the membrane of the filter and out the air vent(s). In embodiments, the vents are hydrophobic which prevent fluid from being ejected, so the priming system can nm without intervention.

Abstract: A pressure measurement pod for blood circuits can include a flexible, moveable, fluid-impermeable diaphragm and can be formed via either a one-shot or a two-shot molding process. A method of manufacturing a pressure measuring device can include providing first and second major mold parts having recesses defining major parts of a housing, and inserting pins in the first and second major mold parts, the pins being shaped to define a flow channel of a molded pressure measuring pod. One of the pins may have a major face that defines an internal surface of a diaphragm. The method may further include closing the first and second major mold parts with the pins therebetween and injection molding a pressure pod housing. Finally, the pressure pod is removed from the mold parts and the pins are withdrawn from the flow channel.

Abstract: A pressure measurement system for use in blood circuits comprised of a pressure sensing pod and a force measurement device. The pressure sensing pod can include a flexible, moveable, fluid-impermeable diaphragm and can be formed via either a one-shot or a two-shot molding process. A mechanical engagement member of the force measurement device engages with a mechanical engagement feature of the diaphragm, and the engagement member is operative to move in concert with movement of the engagement feature of the diaphragm based on pressure variations with the pressure sensing pod. The force measurement device generates and outputs to a processor a signal based on detected force associated with movement of the engagement member.

Abstract: Releasable tubing pinch clamps of a generally U-shaped configuration are described. The embodiments include ones that prevent cross-clamping of the tube by various interlocking features on riser portions of the clamp. Methods and molds for making the pinch clamps are also described. The pinch clamp consists generally of a strip that curves so that its ends can be brought together by manually squeezing the strip at its ends which oppose each other as a result of the strip curve. The strip ends contain locking edges or surfaces that cause the strip ends to interferingly engage with each other and lock together. The strip also contains opposing pinching projections that pinch a tube.

Abstract: Releasable tubing pinch clamps of a generally U-shaped configuration are described. The embodiments include ones that prevent cross-clamping of the tube by various interlocking features on riser portions of the clamp. Methods and molds for making the pinch clamps are also described. For example, a pinch clamp can have a strip that curves so that its ends can be brought together by manually squeezing the strip at its end, which oppose each other as a result of the strip curve. The strip ends have locking edges or surfaces that cause the strip ends to interferingly engage with each other and lock together. The strip also has opposing pinch projections that can pinch a tube.

Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.