Abstract: Multi-layer ensembles of neural subnetworks are disclosed. Implementations can classify inputs indicating various anomalous sensed conditions into probabilistic anomalies using an anomaly subnetwork. Determined probabilistic anomalies are classified into remedial application triggers invoked to recommend or take actions to remediate, and/or report the anomaly. Implementations can select a report type to submit, or a report recipient, based upon the situation state, e.g.

Abstract: The technology disclosed relates to Artificial Intelligence techniques for sharing and managing information across organizational boundaries. Specific embodiments of the technology disclosed include the integration of LLM/LMM-based information comparison to enable alignment on a ground truth (or an agreed upon data standard) across multiple documents related to a community's data, and communicating that alignment to the users in the community. As a result, the users can update data and make amendments to documents affecting related actions among multiple community members. in order to resolve any misalignment between data and physical reality. Information exchange can be securable through verifiable credential technology.

Abstract: The technology disclosed allows for leveraging decentralized credentials to achieve bidirectional authentication between two actors leveraging a messaging platform/system, such as email or another text-based system, verifiable credentials (VCs), and secure web endpoints. It empowers one party (“Sender”) to send a message enclosed with a Verifiable Presentation which allows another party (“Recipient”) to authenticate the message's provenance and the identity of the sender. Moreover, the message contains a link to a secure web endpoint, where the recipient can submit a response signed by their own Verifiable Presentation, allowing the Sender to authenticate the identity of the Recipient. In this way, both participants are able to authenticate each other's identities with an additional factor of authentication, with neither participant being required to share a single service.

Abstract: Multi-layer ensembles of neural subnetworks are disclosed. Implementations can classify inputs indicating various anomalous sensed conditions into probabilistic anomalies using an anomaly subnetwork. Determined probabilistic anomalies are classified into remedial application triggers invoked to recommend or take actions to remediate, and/or report the anomaly. Implementations can select a report type to submit, or a report recipient, based upon the situation state, e.g.

Abstract: Disclosed is a method for authenticating requestors and granting access to a permissioned blockchain network shared among enterprise entities. A decentralized registry of credentialled users, in which credentialled users guard their own access information by keeping a private key of a public-private keypair enables systems to avoid keeping information of a large number of users in large, vulnerable containers. A further method removes authenticated users seeking to be forgotten from the registry of users and deletes any personally identifiable information of the withdrawing users.

Abstract: The technology disclosed allows for leveraging decentralized credentials to achieve bidirectional authentication between two actors leveraging a messaging platform/system, such as email or another text-based system, verifiable credentials (VCs), and secure web endpoints. It empowers one party (“Sender”) to send a message enclosed with a Verifiable Presentation which allows another party (“Recipient”) to authenticate the message's provenance and the identity of the sender. Moreover, the message contains a link to a secure web endpoint, where the recipient can submit a response signed by their own Verifiable Presentation, allowing the Sender to authenticate the identity of the Recipient. In this way, both participants are able to authenticate each other's identities with an additional factor of authentication, with neither participant being required to share a single service.

Abstract: Multi-layer ensembles of neural subnetworks are disclosed. Implementations can classify inputs indicating various anomalous sensed conditions into probabilistic anomalies using an anomaly subnetwork. Determined probabilistic anomalies are classified into remedial application triggers invoked to recommend or take actions to remediate, and/or report the anomaly. Implementations can select a report type to submit, or a report recipient, based upon the situation state, e.g.

Abstract: Disclosed is a method for cross-authenticating non-credentialed devices and trusted blockchain enabled applications using multiple communications modalities and gathering information upon request for a blockchain network.

Abstract: Disclosed is a method for cross-authenticating non-credentialed devices and trusted blockchain enabled applications using multiple communications modalities and gathering information upon request for a blockchain network.

Abstract: Disclosed is a method for authenticating requestors and granting access to a permissioned blockchain network shared among enterprise entities. A decentralized registry of credentialed users, in which credentialed users guard their own access information by keeping a private key of a public-private keypair enables systems to avoid keeping information of a large number of users in large, vulnerable containers. A further method removes authenticated users seeking to be forgotten from the registry of users and deletes any personally identifiable information of the withdrawing users.

Abstract: Disclosed is a method for cross-authenticating non-credentialed devices and trusted blockchain enabled applications using multiple communications modalities and gathering information upon request for a blockchain network.

Abstract: Disclosed is a method for cross-authenticating non-credentialed devices and trusted blockchain enabled applications using multiple communications modalities and gathering information upon request for a blockchain network.

Abstract: Disclosed is a method for cross-authenticating non-credentialed devices and trusted blockchain enabled applications using multiple communications modalities and gathering information upon request for a blockchain network.

Abstract: Communicating with a distributed service in the network computing environment. A method for communicating with a distributed service includes referencing a configuration registry to determine resources and permissions in a potential distributed service entry. A potential distributed service entry identifies a distributed service corresponding to the potential distributed service entry that is authorized to exist by virtue of an entry in the configuration registry for the potential distributed service entry specifying that the distributed service may exist, whether or not the distributed service corresponding to the potential distributed service entry exists. The method further includes using the resource information, attempting to contact the distributed service corresponding to the potential distributed service entry. Permissions of the distributed service corresponding to the potential distributed service entry are verified to match permissions of the potential distributed service entry.

Abstract: Methods and compositions are provided that achieve depletion of a nucleotide pool by means of a phosphate-transferring enzyme such as a nucleoside phosphate or a polyphosphate glucokinase. Depletion of a nucleotide pool using a nucleoside kinase may additionally utilize a phosphotransferase in a second phosphate-transferring reaction.

Abstract: A domain controller hierarchy includes one or more hub domain controllers in communication with one or more local domain controllers, such as local domain controllers at a branch office. The hub domain controller(s) is writable, while the local domain controller(s) is typically read-only. Non-secure and secure information is partitioned to specific local domain controllers at the one or more hub domain controllers. The non-secure and secure information is then passed from the hub domain controller only to the local domain controller associated with the given partition at the hub domain controller on request. For example, a user requests a logon at a client computer system at a local branch office, and the logon is passed from the local domain controller to the hub domain controller. If authenticated, the user logon account is passed to the local domain controller, where it can be cached to authenticate subsequent requests.

Abstract: A domain controller hierarchy includes one or more hub domain controllers in communication with one or more local domain controllers, such as local domain controllers at a branch office. The hub domain controller(s) is writable, while the local domain controller(s) is typically read-only. Non-secure and secure information is partitioned to specific local domain controllers at the one or more hub domain controllers. The non-secure and secure information is then passed from the hub domain controller only to the local domain controller associated with the given partition at the hub domain controller on request. For example, a user requests a logon at a client computer system at a local branch office, and the logon is passed from the local domain controller to the hub domain controller. If authenticated, the user logon account is passed to the local domain controller, where it can be cached to authenticate subsequent requests.

Abstract: A domain controller hierarchy in accordance with implementations of the present invention involves one or more local domain controllers, such as one or more read-only local domain controllers in communication with one or more writable hub domain controllers. The local domain controllers includes a resource manager, such as a Security Account Manager (“SAM”), that manages resources and/or other accounts information received from the writable hub domain controller. When a local user attempts to change the resource at the local domain controller, however, the resource manager chains the request, along with any appropriate identifiers for the request, to the writable hub domain controller, where the request is processed. If appropriate, the hub domain controller sends a response that the resource has been updated as requested and also sends a copy of the updated resource to be cached at the local domain controller.

Abstract: The present invention is directed toward improving the efficiency of chain terminator incorporation by Family B archaeon DNA polymerases. Previously, the low efficiency of ddNTP, and more especially dye-labeled ddNTP, incorporation has limited the usefulness of this group of DNA polymerases in protocols requiring chain terminator incorporation.

Abstract: The present invention relates to the use of site-specific nucleic acid nicking enzymes to create single-stranded regions in duplex nucleic acids. Such single-stranded regions can take the form of gaps interior to the duplex, or terminal single-stranded regions. Single-stranded termini can be crafted to allow linkage of various elements via base-pairing with elements containing a complementary single-stranded region. This joining is useful, for example, in an ordered, oriented assembly of DNA modules to create cloning or expression vectors. This joining is also useful in attaching detection probes and purifying DNA molecules containing the single-stranded region. Gaps are useful in similar applications, including attaching detection or purification probes.