Abstract: Disclosed herein are devices and systems for stimulating and manipulating tissue, such as skin, fascia and muscle tissue, to reduce pain or discomfort. In one aspect, a tissue stimulation and manipulation device includes a manipulating head having a casing with an application area configured to contact at least one site of a subject; and a propulsion source capable of producing mechanical motion or linear energy; the propulsion source and application area are operatively positioned relative to one another such that the propulsion source and contact portions on the application area cooperate to manipulate tissue at the site of the subject. Also disclosed herein are methods for using the disclosed devices and systems to treat skin, fascia and muscle tissue.

Abstract: An in-ear device configured to help a subject manage or reduce pain, discomfort, or other symptoms associated with TMJ disorder. Also disclosed are methods of using optical scanning to create a three dimensional replication of the ear canal that is used to design a customized in-ear device. Also disclosed is a method of helping manage at least one symptom associated with TMD by customizing a series of in-ear device and modifying the devices over time, where each device in the series is customized to the subject.

Abstract: An in-ear orthotic with one or more features to help manage or reduce pain, discomfort, or other symptoms associated with temporomandibular joint disorder. Also disclosed are methods of using optical scanning to create a three dimensional replication of the ear canal that is used to design a customized in-ear orthotic to help manage one or more symptoms of temporomandibular joint disorder.

Abstract: An in-ear device with one or more proprioceptive features for providing an indication to a subject to help manage or reduce pain, discomfort, or other symptoms associated with TMJ disorder. In some embodiments, the one or more proprioceptive features are active and/or passive indicators. Also disclosed are methods of using optical scanning to create a three dimensional replication of the ear canal that is used to design a customized in-ear device.

Abstract: An in-ear device configured to help a subject manage or reduce pain, discomfort, or other symptoms associated with TMJ disorder. Also disclosed are methods of using optical scanning to create a three dimensional replication of the ear canal that is used to design a customized in-ear device. Also disclosed is a method of helping manage at least one symptom associated with TMD by providing an in-ear device for wear while the subject is awake and providing a bite guard for wear at night while the subject is sleeping.

Abstract: An in-ear device with at least one sensor configured to generate a signal to help a subject manage or reduce pain, discomfort, or other symptoms associated with TMJ disorder. Also disclosed are methods of using optical scanning to create a three dimensional replication of the ear canal that is used to design a customized in-ear device.

Abstract: An in-ear device with one or more proprioceptive features for providing an indication to a subject to help manage or reduce pain, discomfort, or other symptoms associated with TMJ disorder. Also disclosed are methods of using optical scanning to create a three dimensional replication of the ear canal that is used to design a customized in-ear device. In some embodiments, the in-ear device is customized based on the configuration of the subject's ear canal when the subject's jaw is in the therapeutic or optimal position.