Abstract: Methods and systems of routing targeted content to networked destinations are described. The targeting may be performed utilizing demographic targeting, property targeting, behavioral targeting, and/or event targeting. An adjusted value for a targeted guaranteed content item associated with an entity may be dynamically calculated using a previously specified value communicated with the entity and/or historical delivery performance for the targeted guaranteed content item. A content request may be received from a user agent. A determination is made as to whether the targeted guaranteed content item is eligible to be delivered to the user agent using a targeting criterion and a dynamic pace setting. The targeted guaranteed content item may participate, along with real time open market bids, in a real time impression auction. The adjusted value may be used in the real time auction to determine which item of content is to be routed to the user agent.