Abstract: The present disclosure provides apparatuses and methods for treating conditions such as chronic daily headache, cluster headache, tension headache, migraine, or acute headache of a patient. In example methods, a cryotherapy element is introduced into the nasal cavity or pterygopalatine fossa to cool or cryoablate at least one of a nasal nerve tissue or nasal blood vessel. The cryotherapy element may be introduced into the nasal cavity in a collapsed position, and prior to cooling a target treatment site may be expanded to an expanded configuration.

Abstract: A heat exchanger is provided that can include furcating unit cells coupled with each other. Each of the unit cells can be elongated along an axis and include a sidewall that defines annular ring openings on opposite ends of the unit cell along the axis. The sidewall also can define undulating annular rings between the annular ring openings and axially separated from each other along the axis. The sidewall can further define angled openings into the unit cell both above and below each of the undulating annular rings. At least a first opening of the annular ring openings and the angled openings can be configured to be an inlet to receive a first fluid into the unit cell and at least a second opening of the annular ring openings and the angled openings configured to be an outlet through which the first fluid exits the unit cell.

Abstract: The present technology includes systems and methods for invasively adjusting implantable devices for selectively controlling fluid flow between a first body region and a second body region of a patient. For example, in many of the embodiments described herein, a catheter can be used to mechanically and/or electrically engage an implanted medical device. Once the catheter engages the medical device, the catheter can (i) increase a dimension associated with the medical device, such as through mechanical expansion forces, and/or (ii) decrease a dimension associated with the medical device, such as by heating a shape memory component of the medical device above a phase transition temperature.

Abstract: A heat exchanger includes a core defining a first passageway for a first fluid flow and a second passageway for a second fluid flow. The core includes an assembly of a plurality of unit cells coupled together. Each unit cell defines a first passageway portion within an interior volume and a second passageway portion at an exterior surface. Each unit cell includes a plurality of first openings into the interior volume and forms the second passageway in volumes between the plurality of unit cells. The assembly is shaped to combine and divide the first fluid in the first passageway portion and combine and divide the second fluid in the second passageway portion during exchange of heat between the first fluid and the second fluid. Each second passageway portion receives the second fluid from three other second passageway portions.

Abstract: A surgical apparatus includes a housing, a test port retainer, a pressure test chamber, and an image capture assembly. The housing includes a pressure test port. The test port retainer includes a test port retainer housing, a probe seal, and a liquid exclusion barrier. In one aspect, the test port retainer also includes a hydrophobic membrane mounted within the test port retainer housing. The pressure test chamber includes a manifold and a central tube. The first end of the central tube is affixed to the image capture assembly to form a pressure seal, and the second end of the central tube is coupled to the test port retainer so that the pressure test port communicates with the interior volume of the central tube through the test port retainer.

Abstract: Described are techniques for managing data locations of derived storage objects. The techniques include accessing a primary metadata tree providing a lookup path using a virtual address to locate data for a primary object in physical storage pointed to by a leaf node of the primary metadata tree and providing a sub-tree from a leaf node of the primary metadata tree associated with the primary object, the sub-tree providing lookup paths using virtual addresses for derived objects. Wherein a derived object is a view of the primary object at a specific point in time, with copy leaf nodes of the sub-tree pointing to stored data of the derived objects. The techniques further include maintaining an ancestry graph associated with the sub-tree with the ancestry graph linking derived object identifiers to provide an ancestral chain lookup to identify derived object identifiers of the closest stored physical data of a derived object.

Abstract: A bulk dry cement may comprise a cement; a solid particle; and a liquid resin accelerator, wherein the liquid resin accelerator is disposed on a surface of the solid particle.

Abstract: A system and method for operating a plurality of games of chance. The gaming system includes a primary game display area and a secondary game display area. The plurality of games includes at least a plurality of electronic table games including two or more electronic table games from a group of table games including, craps, baccarat, roulette, blackjack, three-card poker, pai gow poker, Caribbean stud and big 6 wheel. The processing of the two or more electronic table games includes a separate and discrete game state engine for each of the two or more electronic table games. High hold percentage side bets are offered to increase the hold percentage of at least one table game and the overall hold percentage of the gaming system.

Abstract: An endoscope includes a first subassembly, a second subassembly, a third subassembly, and a fourth subassembly, which are sequentially assembled and tested in making the endoscope. The first subassembly includes a pressure-sealed electrical cable connected to an image capture unit. The second subassembly includes the first subassembly, a shell, a light pipe, and a lid. The third subassembly includes the second subassembly, a central tube, and a flange. The fourth subassembly includes the third subassembly, a base, a shaft, and optionally an articulating assembly.

Abstract: A computer-assisted surgical system simultaneously provides visible light and alternate modality images that identify tissue or increase the visual salience of features of clinical interest that a surgeon normally uses when performing a surgical intervention using the computer-assisted surgical system. Hyperspectral light from tissue of interest is used to safely and efficiently image that tissue even though the tissue may be obscured in the normal visible image of the surgical field. The combination of visible and hyperspectral images are analyzed to provide details and information concerning the tissue or other bodily function that were not previously available.

Abstract: A surgical apparatus includes a housing, a test port retainer, a pressure test chamber, and an image capture assembly. The housing includes a pressure test port. The test port retainer includes a test port retainer housing, a probe seal, and a liquid exclusion barrier. In one aspect, the test port retainer also includes a hydrophobic membrane mounted within the test port retainer housing. The pressure test chamber includes a manifold and a central tube. The first end of the central tube is affixed to the image capture assembly to form a pressure seal, and the second end of the central tube is coupled to the test port retainer so that the pressure test port communicates with the interior volume of the central tube through the test port retainer.

Abstract: The present technology relates to interatrial shunting systems and methods. In some embodiments, the present technology includes a method for monitoring a shunting element implanted in a patient and having a lumen fluidly coupling cavities of the patient's heart. The method can comprise obtaining first and second radiographic images of at least two radiopaque elements associated with the lumen of the shunting element. A spatial relationship between the radiopaque elements varies according to a size of the lumen. The first radiographic image can be taken from a first viewing angle and the second radiographic image can be taken from a second viewing angle generally orthonormal to the first viewing an The method also includes determining the size of the lumen based, at least in part. on locations of the radiopaque elements in the first and second radiographic images.

Abstract: Systems and related methods for identifying and/or ablating targeted nerves are provided. A probe with stimulating electrodes and/or ablation members are provided. The probe may be inserted into a nasal cavity and current may be introduced through the electrodes to stimulate a targeted area. The response to stimulation may be used to identify the targeted nerve. Once identified, the ablation member may ablate the targeted nerve.

Abstract: The present technology includes systems and methods for invasively adjusting implantable devices for selectively controlling fluid flow between a first body region and a second body region of a patient. For example, in many of the embodiments described herein, a catheter can be used to mechanically and/or electrically engage an implanted medical device. Once the catheter engages the medical device, the catheter can (i) increase a dimension associated with the medical device, such as through mechanical expansion forces, and/or (ii) decrease a dimension associated with the medical device, such as by heating a shape memory component of the medical device above a phase transition temperature.

Abstract: The present disclosure relates to the use of MASP-2 inhibitors and/or MASP-3 inhibitors and compositions comprising the same for treatment of sickle cell disease, including treatment, reduction, and/or prevention of sickle cell disease symptoms or manifestations.

Abstract: Described here are methods and apparatuses for tracking a clot material within a lumen of a suction catheter. For example, an apparatus as described herein may include a flexible elongate body having a suction lumen, a first pair of electrodes within the suction lumen, a second pair of electrodes proximal to the first pair of electrodes, and a controller configured to track a clot material within the suction lumen based on signals from the first pair of electrodes and the second pair of electrodes.

Abstract: Apparatus and associated methods relate to a bi-directional conduit system including a core configured to traverse a container wall and having independent, substantially parallel lumens and a fitting fluidly connected to each lumen on each side of the wall. In an illustrative example, the conduit system may include at least one valve configured to selectively restrict fluid flow in at least one lumen. The core may be flexible. A coupling assembly may be configured to releasably couple the core to the wall. Apparatus and methods further relate to a system including a base module with a control input and a fluid transport system including an impeller powered by the base module to convey fluid via a conduit in response to the control input, wherein in a stowage mode, the base module is configured to store the conduit and to mechanically support, releasably coupled, the impeller to the base module.

Abstract: Systems and related methods for identifying and/or ablating targeted nerves are provided. A probe with stimulating electrodes and/or ablation members are provided. The probe may be inserted into a nasal cavity and current may be introduced through the electrodes to stimulate a targeted area. The response to stimulation may be used to identify the targeted nerve. Once identified, the ablation member may ablate the targeted nerve.

Abstract: Described here are methods and apparatuses for tracking a clot material within a lumen of a suction catheter. For example, an apparatus as described herein may include a flexible elongate body having a suction lumen, a first pair of electrodes within the suction lumen, a second pair of electrodes proximal to the first pair of electrodes, and a controller configured to track a clot material within the suction lumen based on signals from the first pair of electrodes and the second pair of electrodes.

Abstract: Apparatus and associated methods relate to an environmental control system including a fluid driver configured to releasably couple to a buoyant module. In an illustrative example, in a deployment mode, the fluid driver may be brought into register with and releasably coupled to the buoyant module. The fluid driver, for example, be supported by the buoyant module in a body of water. A control unit may, for example, selectively provide energy to the fluid driver such that the fluid driver induces fluid to flow from the body of fluid to a reservoir by a conduit. The control unit may be configured to mechanically support the fluid driver in a stowage mode. Various embodiments may advantageously allow a user to selectively deploy a livewell environment control from a stowed mode into a deployed mode.