Patents by Inventor William Jeffries

William Jeffries has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260146990
    Abstract: A system and method for predictive modeling of cellular systems assesses compound effectiveness on cellular metabolic and inflammatory states. Cellular samples are exposed to metabolic MRX sensors detecting oxidative stress, reporting cytoskeletal organization, or monitoring mitochondrial morphology, dynamics, or compartment-specific redox activity. Images of MRX sensor-labeled samples are captured using an imaging device and analyzed by trained predictive models to determine compound impact on immunological activation, inflammatory status, oxidative stress, mitochondrial function, and bio-energetic state. The system supports multisensor integration and spectral unmixing to generate multidimensional metabolic or ROS related MRX fingerprints that characterize cellular phenotypes, drug responses, and enable comparison to reference states. Preprocessing modules perform image normalization, augmentation, segmentation, and feature extraction to enhance model performance.
    Type: Application
    Filed: November 25, 2025
    Publication date: May 28, 2026
    Applicant: George Mason University
    Inventors: Nadine Kabbani, Patricia Sinclair, William Jeffries
  • Publication number: 20100169639
    Abstract: A secure data exchange and access system, method, and architecture for allow web-based data transfer with improved security and scalability. The system incorporates and enables serialized pedigree systems while allowing security for storing, authenticating, and tracking a change of custody of a serialized item along a transfer chain. A plurality of independent databases, respectively blind to each other but for a global construct, retains pieces of information along a product supply chain. Specific encryption/decryption protocols enable secure information transfer in a number of modes including a post point of sale anti-counterfeiting system that includes a process for consumer involvement as a triggering mechanism.
    Type: Application
    Filed: March 17, 2008
    Publication date: July 1, 2010
    Inventors: William Jeffries, Kamal Mustafa
  • Publication number: 20060137090
    Abstract: A wireless water flow monitoring and leak detection system and method are provided. The system includes a base station, a memory, and a central processing unit configured to control the operation of the system and to analyze stored data. A plurality of highly-sensitive wireless flow sensor nodes are each installed individually on a supply line of a water fixture in a facility having a plurality of water fixtures. The wireless flow sensor nodes can periodically read and store a data point corresponding to either a flow condition or a no flow condition occurring at the water fixture. A plurality of coordinator nodes are configured to wirelessly relay data between the plurality of wireless flow sensor nodes and the base station. The base station is configured to determine based on an analysis of the stream of data points whether a leak exists in any of the water fixtures, and if a leak is determined to exist, a maintenance alert is generated.
    Type: Application
    Filed: December 28, 2005
    Publication date: June 29, 2006
    Inventors: William Jeffries, David Parsons, Darren Parsons