Abstract: A musical instrument snake cable that interconnects audio components for use with a musical instrument in a manner consistent with certain embodiments of the present invention has a plurality of shielded signal-carrying wire groups for carrying unbalanced signals between a frontline end and a backline end. An electrical connector terminates the frontline end and the backline end of each signal-carrying wire group. A power-carrying wire group is provided having frontline end and a backline end with first and second electrical connectors terminating the frontline end and the backline end of each power-carrying wire group. An insulating sleeve surrounds the plurality of shielded signal-carrying wire groups and the power-carrying wire group. In one embodiment, the shielded signal-carrying wire groups are each made up of a shielded twisted pair.