Patents by Inventor William John Drury III

William John Drury III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof
    Patent number: 12115225
    Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: October 15, 2024
    Assignees: ASTRAZENECA AB, IONIS PHARMACEUTICALS, INC.
    Inventors: Brett P. Monia, Thazha P. Prakash, Garth A. Kinberger, Richard Lee, Punit P. Seth, Shalini Andersson, Eva Carina Ämmälä, Daniel Laurent Knerr, Maria Astrid Ölwegård-Halvarsson, Eric Valeur, William John Drury, III
  • GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF
    Publication number: 20240293563
    Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.
    Type: Application
    Filed: February 23, 2024
    Publication date: September 5, 2024
    Inventors: Brett P. MONIA, Thazha P. PRAKASH, Garth A. KINBERGER, Richard LEE, Punit P. SETH, Michael OESTERGAARD, Mehran NIKAN, Shalini ANDERSSON, Eva Carina AMMALA, Daniel Laurent KNERR, Maria OLWEGARD-HALVARSSON, William John DRURY, III, Eric VALEUR
  • LINKAGE MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
    Publication number: 20240002851
    Abstract: The present disclosure provides oligomeric compounds (including oligomeric compounds that are antisense agents or portions thereof) comprising a modified oligonucleotide having at least one modified internucleoside linking group.
    Type: Application
    Filed: January 25, 2023
    Publication date: January 4, 2024
    Applicant: Ionis Pharmaceuticals, Inc.
    Inventors: Brooke A. Anderson, Xue-Hai Liang, William John Drury, III, Michael Oestergaard, Michael T. Migawa, Punit P. Seth
  • Linkage modified oligomeric compounds and uses thereof
    Patent number: 11629348
    Abstract: The present disclosure provides oligomeric compounds (including oligomeric compounds that are antisense agents or portions thereof) comprising a modified oligonucleotide having at least one modified internucleoside linking group.
    Type: Grant
    Filed: February 15, 2022
    Date of Patent: April 18, 2023
    Assignee: Ionis Pharmaceuticals, Inc.
    Inventors: Brooke A. Anderson, Xue-hai Liang, William John Drury, III, Michael Oestergaard, Michael T. Migawa, Punit P. Seth
  • TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS
    Publication number: 20220290140
    Abstract: Featured are trans-cyclooctene and tetrazine compounds. Also provided are methods for evaluating the biodistribution and/or concentration of a biomolecule in a subject.
    Type: Application
    Filed: August 19, 2020
    Publication date: September 15, 2022
    Inventors: Brendon Ellery COOK, Maciej Adam KALISZCZAK, Laurent MARTARELLO, Nathan Edward GENUNG, Sivaraman DANDAPANI, Eric Edward SWAYZE, William John DRURY, III, Chrissa Ann DWYER
  • LINKAGE MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
    Publication number: 20220186222
    Abstract: The present disclosure provides oligomeric compounds (including oligomeric compounds that are antisense agents or portions thereof) comprising a modified oligonucleotide having at least one modified internucleoside linking group.
    Type: Application
    Filed: February 15, 2022
    Publication date: June 16, 2022
    Applicant: Ionis Pharmaceuticals, Inc.
    Inventors: Brooke A. Anderson, Xue-hai Liang, William John Drury, III, Michael Oestergaard, Michael T. Migawa, Punit P. Seth
  • COMPOUNDS AND METHODS FOR MODULATING SMN2
    Publication number: 20220064638
    Abstract: Provided are compounds, methods, and pharmaceutical compositions for modulating SMN2 RNA and/or protein in a cell or subject. Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least one symptom of a neurodegenerative disorder. Such symptoms include reduced muscle strength; inability or reduced ability to sit upright, to stand, and/or walk; reduced neuromuscular activity; reduced electrical activity in one or more muscles; reduced respiration; inability or reduced ability to eat, drink, and/or breathe without assistance; loss of weight or reduced weight gain; and/or decreased survival.
    Type: Application
    Filed: February 26, 2021
    Publication date: March 3, 2022
    Applicant: Ionis Pharmaceuticals, Inc.
    Inventors: Frank Rigo, Thazha P. Prakash, Kar Yun Karen Ling, W. Brad Wan, William John Drury, III
  • GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof
    Publication number: 20210346509
    Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.
    Type: Application
    Filed: April 15, 2021
    Publication date: November 11, 2021
    Inventors: Brett P. Monia, Thazha P. Prakash, Garth A. KINBERGER, Richard Lee, Punit P. Seth, Shalini Andersson, Eva Carina Ämmälä, Daniel Laurent Knerr, Maria Astrid Ölwegård-Halvarsson, Eric Valeur, William John Drury, III
  • GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF
    Publication number: 20200268898
    Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.
    Type: Application
    Filed: November 7, 2018
    Publication date: August 27, 2020
    Inventors: Brett P. MONIA, Thazha P. PRAKASH, Garth A. KINBERGER, Richard LEE, Punit P. SETH, Michael OESTERGAARD, Mehran NIKAN, Shalini ANDERSSON, Eva Carina AMMALA, Daniel Laurent KNERR, Maria OLWEGARD-HALVARSSON, William John DRURY, III, Eric VALEUR
  • GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof
    Publication number: 20190134214
    Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.
    Type: Application
    Filed: May 4, 2017
    Publication date: May 9, 2019
    Inventors: Brett P. Monia, Thazha P. Prakash, Garth A. KINBERGER, Richard Lee, Punit P. Seth, Shalini Andersson, Eva Carina Ämmälä, Daniel Laurent Knerr, Maria Astrid Ölwegård-Halvarsson, Eric Valeur, William John Drury III