Patents by Inventor William Joseph Kelly, III

William Joseph Kelly, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS COMPRISING FUSION PROTEINS FOR THE IDENTIFICATION OF IMMUNOTHERAPY CELLS
    Publication number: 20240060043
    Abstract: Fusion proteins, comprising at least one single chain antibody fragment (scFV), and a cancer antigen or marker, or a fragment thereof are provided. The scFV is capable of selectively binding to a cytokine released by chimeric antigen receptor (CAR) expressing cell such as interferon gamma (IFN-?) or tumor necrosis factor alpha (TNF-?). The cancer antigen or marker may comprise the extracellular domain of CD19. Methods for isolating or purifying CAR expressing cells using fusion proteins are provided.
    Type: Application
    Filed: July 24, 2023
    Publication date: February 22, 2024
    Applicants: Villanova University, Lankenau Institute for Medical Research
    Inventors: William Joseph Kelly, III, Justin Thomas Fisher, Scott Kendall Dessain