Patents by Inventor William K. Schmidt

William K. Schmidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10434178
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: October 8, 2019
    Assignee: Adynxx Sub, Inc.
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K. Schmidt, Tony Yaksh, David C. Yeomans
  • Publication number: 20180015165
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Application
    Filed: April 5, 2017
    Publication date: January 18, 2018
    Applicant: Adynxx, Inc.
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K. Schmidt, Tony Yaksh, David C. Yeomans
  • Patent number: 9700624
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Grant
    Filed: May 9, 2013
    Date of Patent: July 11, 2017
    Assignee: Adynxx, Inc.
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K Schmidt, Tony Yaksh, David C Yeomans
  • Publication number: 20150126554
    Abstract: Methods of preventing and treating gastrointestinal dysfunction, particularly postoperative ileus and post-partum ileus, in a patient undergoing surgery or other biological stress by administering 4-aryl-piperidine derivatives are disclosed.
    Type: Application
    Filed: January 15, 2015
    Publication date: May 7, 2015
    Inventors: David D. Christ, Bruce A. Wallin, Deanne D. Garver, William K. Schmidt, David Jackson
  • Publication number: 20150111956
    Abstract: This invention relates generally to in vivo delivery of active ingredient formulations. More particularly, this invention relates to formulations of active ingredients that further comprise an agent, methods of making such formulations, and methods of using the same.
    Type: Application
    Filed: May 9, 2013
    Publication date: April 23, 2015
    Inventors: Julien Mamet, Scott Harris, George Miljanich, Rick Orr, William K Schmidt, Tony Yakash, David C Yeomans
  • Patent number: 8946262
    Abstract: Methods of preventing and treating gastrointestinal dysfunction, particularly postoperative ileus and post-partum ileus, in a patient undergoing surgery or other biological stress by administering 4-aryl-piperidine derivatives are disclosed.
    Type: Grant
    Filed: November 29, 2004
    Date of Patent: February 3, 2015
    Assignee: Adolor Corporation
    Inventors: David D Christ, Bruce A Wallin, Deanne D Garver, William K Schmidt, David Jackson
  • Patent number: 7696220
    Abstract: Methods for the treatment of ileus are disclosed wherein the peripheral mu opioid antagonist methylnaltrexone is administered.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: April 13, 2010
    Assignee: Adolor Corporation
    Inventors: John J. Farrar, Peter J. Schied, William K. Schmidt, Randall L. Carpenter
  • Publication number: 20020188005
    Abstract: Novel methods for the treatment and/or prevention of ileus. The methods may comprise administering to a patient an effective amount of a peripheral mu opioid antagonist compound. Preferred compounds for use in the methods include piperidine-N-alkylcarboxylates, quaternary morphinans, opium alkaloid derivatives and quaternary benzomorphans. The methods are particularly suitable for treating and/or preventing postsurgical ileus and postpartum ileus.
    Type: Application
    Filed: June 13, 2002
    Publication date: December 12, 2002
    Applicant: Adolor Corporation
    Inventors: John J. Farrar, Peter J. Schied, William K. Schmidt, Randall L. Carpenter
  • Patent number: 6469030
    Abstract: Methods for the treatment and/or prevention of ileus are disclosed. The methods comprise administering to a patient an effective amount of a peripheral mu opioid antagonist compound. Preferred compounds for use in the methods include piperidine-N-alkylcarboxylates.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: October 22, 2002
    Assignee: Adolor Corporation
    Inventors: John J. Farrar, Peter J. Schied, William K. Schmidt, Randall L. Carpenter
  • Publication number: 20010036951
    Abstract: Novel methods for the treatment and/or prevention of ileus. The methods may comprise administering to a patient an effective amount of a peripheral mu opioid antagonist compound. Preferred compounds for use in the methods include piperidine-N-alkylcarboxylates, quaternary morphinans, opium alkaloid derivatives and quaternary benzomorphans. The methods are particularly suitable for treating and/or preventing postsurgical ileus and postpartum ileus.
    Type: Application
    Filed: November 29, 2000
    Publication date: November 1, 2001
    Inventors: John J. Farrar, Peter J. Schied, William K. Schmidt, Randall L. Carpenter
  • Patent number: 4569937
    Abstract: Pharmaceutical compositions of narcotic analgesics and ibuprofen have been found to exhibit unexpectedly enhanced analgesic activity by applying an analysis model which considers data characterizing the analgesic effect of both the pure components as well as the fixed dose ratio combinations. This synergism enables the use of lower doses of either or both drugs with a concomitant reduction in risk of possible side effects.
    Type: Grant
    Filed: February 11, 1985
    Date of Patent: February 11, 1986
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Geraldine L. Baker, William K. Schmidt
  • Patent number: 4407805
    Abstract: Pharmaceutical compositions of nalbuphine and zomepirac have been found to exhibit unexpectedly enhanced analgesic activity by applying an analysis model which considers data characterizing the analgesic effect of both the pure components as well as the fixed dose ratio combinations. This synergism enables the use of lower doses of either or both drugs with a concomitant reduction in risk of possible side effects.
    Type: Grant
    Filed: June 30, 1982
    Date of Patent: October 4, 1983
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William K. Schmidt
  • Patent number: 4407804
    Abstract: Pharmaceutical compositions of nalbuphine and indomethacin have been found to exhibit unexpectedly enhanced analgesic activity by applying an analysis model which considers data characterizing the analgesic effect of both the pure components as well as the fixed dose ratio combinations. This synergism enables the use of lower doses of either or both drugs with a concomitant reduction in risk of possible side effects.
    Type: Grant
    Filed: June 30, 1982
    Date of Patent: October 4, 1983
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William K. Schmidt
  • Patent number: 4404208
    Abstract: Pharmaceutical compositions of nalbuphine and tiflamizole have been found to exhibit unexpectedly enhanced analgesic activity by applying an analysis model which considers data characterizing the analgesic effect of both the pure components as well as the fixed dose ratio combinations. This synergism enables the use of lower doses of either or both drugs with a concomitant reduction in risk of possible side effects.
    Type: Grant
    Filed: June 30, 1982
    Date of Patent: September 13, 1983
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William K. Schmidt
  • Patent number: 4404209
    Abstract: Pharmaceutical compositions of nalbuphine and sulindac have been found to exhibit unexpectedly enhanced analgesic activity by applying an analysis model which considers data characterizing the analgesic effect of both the pure components as well as the fixed dose ratio combinations. This synergism enables the use of lower doses of either or both drugs with a concomitant reduction in risk of possible side effects.
    Type: Grant
    Filed: June 30, 1982
    Date of Patent: September 13, 1983
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William K. Schmidt
  • Patent number: 4404210
    Abstract: Pharmaceutical compositions of nalbuphine and ibuprofen have been found to exhibit unexpectedly enhanced analgesic activity by applying an analysis model which considers data characterizing the analgesic effect of both the pure components as well as the fixed dose ratio combinations. This synergism enables the use of lower doses of either or both drugs with a concomitant reduction in risk of possible side effects.
    Type: Grant
    Filed: June 30, 1982
    Date of Patent: September 13, 1983
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William K. Schmidt
  • Patent number: 4404211
    Abstract: Pharmaceutical compositions of nalbuphine and flurbiprofen have been found to exhibit unexpectedly enhanced analgesic activity by applying an analysis model which considers data characterizing the analgesic effect of both the pure components as well as the fixed dose ratio combinations. This synergism enables the use of lower doses of either or both drugs with a concomitant reduction in risk of possible side effects.
    Type: Grant
    Filed: June 30, 1982
    Date of Patent: September 13, 1983
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William K. Schmidt
  • Patent number: 4402962
    Abstract: Pharmaceutical compositions of nalbuphine and 4,5-bis(4-methoxyphenyl)-2-(trifluoromethylsulfonyl)-1H-imidazole have been found to exhibit unexpectedly enhanced analgesic activity by applying an analysis model which considers data characterizing the analgesic effect of both the pure components as well as the fixed dose ratio combinations. This synergism enables the use of lower doses of either or both drugs with a concomitant reduction in risk of possible side effects.
    Type: Grant
    Filed: June 30, 1982
    Date of Patent: September 6, 1983
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: William K. Schmidt
  • Patent number: 4282215
    Abstract: A composition consisting essentially of nalbuphine and acetylsalicylic acid, derivative or salt thereof, gives unexpectedly enhanced analgetic activity.
    Type: Grant
    Filed: July 28, 1980
    Date of Patent: August 4, 1981
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: John R. Dudzinski, William K. Schmidt
  • Patent number: 4260629
    Abstract: Unexpectedly enhanced relief of pain in a mammal is obtained by oral administration of a composition consisting essentially of zomepirac or a pharmaceutically suitable salt thereof and acetaminophen.
    Type: Grant
    Filed: October 25, 1979
    Date of Patent: April 7, 1981
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: William K. Schmidt, Christine Smith, Dewey H. Smith, Jr., Vernon G. Vernier