Patents by Inventor William K. Seltzer

William K. Seltzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11512352
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: November 29, 2022
    Assignee: Athena Diagnostics, Inc.
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan K. Allen, Sat Dev Batish, Hui Zhu
  • Publication number: 20200149107
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Application
    Filed: August 20, 2019
    Publication date: May 14, 2020
    Applicant: Athena Diagnostics, Inc.
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan K. Allen, Sat Dev Batish, Hui Zhu
  • Publication number: 20170166970
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Application
    Filed: February 21, 2017
    Publication date: June 15, 2017
    Applicant: Athena Diagnostics, Inc.
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan K. Allen, Sat Dev Batish, Hui Zhu
  • Patent number: 9611512
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: April 4, 2017
    Assignee: ATHENA DIAGNOSTICS, INC.
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan K. Allen, Sat Dev Batish, Hui Zhu
  • Publication number: 20140323318
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Application
    Filed: July 11, 2014
    Publication date: October 30, 2014
    Inventors: Corey D. BRAASTAD, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan K. Allen, Sat Dev Batish, Hui Zhu
  • Patent number: 8785122
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Grant
    Filed: June 4, 2012
    Date of Patent: July 22, 2014
    Assignee: Athena Diagnostics, Inc.
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan Allen, Sat Dev Batish, Hui Zhu
  • Publication number: 20120237934
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Application
    Filed: June 4, 2012
    Publication date: September 20, 2012
    Applicant: Athena Diagnostics, Inc.
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan Allen, Sat Dev Batish, Hui Zhu
  • Patent number: 8192933
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: June 5, 2012
    Assignee: Athena Diagnostics, Inc.
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan Allen, Sat Dev Batish, Hui Zhu
  • Publication number: 20100167305
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Application
    Filed: March 11, 2010
    Publication date: July 1, 2010
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan Allen, Sat Dev Batish, Hui Zhu
  • Patent number: 7704691
    Abstract: Methods of identifying polymorphisms associated with ataxia-ocular apraxia 2 (AOA2), are described. The polymorphisms associated with AOA2 include specific mutations in the senataxin (SETX) gene. Also described are methods of diagnosis of AOA2, as well as methods of assessing an individual for carrier status for AOA2.
    Type: Grant
    Filed: January 22, 2007
    Date of Patent: April 27, 2010
    Assignee: Athena Diagnostics, Inc.
    Inventors: Corey D. Braastad, Narasimhan Nagan, Jeffrey G. Jones, William K. Seltzer, Susan Allen, Sat Dev Batish, Hui Zhu
  • Patent number: 7521190
    Abstract: The subject invention relates to nucleic acid sequences for detection of mutations in a PKD-1 or PKD-2 gene, as well as biomarkers for ADPKD. The invention further relates to methods for diagnosing ADPKD in an individual, and kits for performing the methods of the invention. The invention also provides a method for determining in an individual the presence or absence of a mutant PKD gene.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: April 21, 2009
    Assignee: Athena Diagnostics, Inc.
    Inventors: Jeffrey G. Jones, Aidan N. Hennigan, John A. Curran, Susan K. Allen, Normand J. Robichaud, Jing Wang, Kerry E. Flynn, Jorge A. Garcés, Christopher M. Palatucci, William K. Seltzer
  • Patent number: 7273701
    Abstract: The subject invention relates to nucleic acid sequences for detection of mutations in a PKD-1 or PKD-2 gene, as well as biomarkers for ADPKD. The invention further relates to methods for diagnosing ADPKD in an individual, and kits for performing the methods of the invention. The invention also provides a method for determining in an individual the presence or absence of a mutant PKD gene.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: September 25, 2007
    Assignee: Athena Diagnostics, Inc.
    Inventors: Jeffrey G. Jones, Aidan N. Hennigan, John A. Curran, Susan K. Allen, Normand J. Robichaud, Jing Wang, Kerry E. Flynn, Jorge A. Garcés, Christopher M. Palatucci, William K. Seltzer
  • Patent number: 6001576
    Abstract: Specific mutations in the connexin-32 gene that are associated with X-linked Charcot-Marie-Tooth (CMT) disease are disclosed. Methods of diagnosing X-linked CMT disease are also disclosed. Methods include hybridization analysis, such as Southern or Northern analysis, which use hybridization of mutant connexin-32 nucleic acid probes to connexin-32 genes; direct mutation analysis by restriction digest; sequencing of the connexin-32 gene; hybridization of an allele-specific oligonucleotide with genomic DNA; or identification of mutant connexin-32 proteins. Mutant connexin-32 nucleic acid probes are also disclosed. The mutant connexin-32 nucleic acid probes have a mutation in at least one of the following codons: 13, 16, 20, 28, 29, 41, 75, 79, 80, 85, 86, 94, 106, 124, 131, 158, 161, 169, 178, 180, 189, 191, 193, 219, 220, 230, and 267.
    Type: Grant
    Filed: May 19, 1998
    Date of Patent: December 14, 1999
    Assignee: Athena Diagnostics, Inc.
    Inventors: Uma Ananth, Michael A. Boss, William K. Seltzer, Charleen M. Sullivan