Patents by Inventor William Kappel

William Kappel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060148090
    Abstract: A metal chelating composition having the formula: wherein Q is a carrier; S1 is a spacer; L is -A-T-CH(X)— or —C(?O)—; A is an ether, thioether, selenoether, or amide linkage; T is a bond or substituted or unsubstituted alkyl or alkenyl; X is —(CH2)kCH3, —(CH2)kCOOH, —(CH2)kSO3H, —(CH2)kPO3H2, —(CH2)kN(J)2, or —(CH2)kP(J)2, preferably —(CH2)kCOOH or —(CH2)kSO3H; k is an integer from 0 to 2; J is hydrocarbyl or substituted hydrocarbyl; Y is —COOH, —H, —SO3H, —PO3H2, —N(J)2, or —P(J)2, preferably, —COOH; Z is —COOH, —H, —SO3H, —PO3H2, —N(J)2, or —P(J)2, preferably, —COOH; and i is an integer from 0 to 4, preferably 1 or 2.
    Type: Application
    Filed: March 1, 2006
    Publication date: July 6, 2006
    Applicant: Sigma-Aldrich Co.
    Inventors: William Kappel, Vankatappa Viswanatha, Handong Li, Richard Mehigh, John Dapron
  • Publication number: 20050123968
    Abstract: A high capacity assay platform capable of binding target molecules includes a substrate and a polymer matrix attached to the substrate. The polymer matrix comprises a plurality of polymer molecules where at least some of the polymer molecules are covalently attached directly to the substrate and at least some of which molecules are crosslinked to other polymer molecules. Some of the polymer molecules have at least one binding ligand covalently attached thereto, and the density of the polymer matrix on the substrate is at least 2 ?g/cm2.
    Type: Application
    Filed: November 5, 2004
    Publication date: June 9, 2005
    Applicant: Sigma-Aldrich Co.,
    Inventors: John Dapron, William Kappel, Handong Li
  • Publication number: 20050118709
    Abstract: A high capacity assay platform capable of binding target molecules includes a substrate and a polymer matrix attached to the substrate. The polymer matrix comprises a plurality of polymer molecules where at least some of the polymer molecules are covalently attached directly to the substrate and at least some of which molecules are crosslinked to other polymer molecules. Some of the polymer molecules have at least one binding ligand covalently attached thereto, and the density of the polymer matrix on the substrate is at least 2 ?g/cm2.
    Type: Application
    Filed: November 5, 2004
    Publication date: June 2, 2005
    Applicant: Sigma-Aldrich Co.
    Inventors: John Dapron, William Kappel, Handong Li
  • Publication number: 20050119415
    Abstract: A high capacity assay platform capable of binding target molecules includes a substrate and a polymer matrix attached to the substrate. The polymer matrix comprises a plurality of polymer molecules where at least some of the polymer molecules are covalently attached directly to the substrate and at least some of which molecules are crosslinked to other polymer molecules. Some of the polymer molecules have at least one binding ligand covalently attached thereto, and the density of the polymer matrix on the substrate is at least 2 ?g/cm2.
    Type: Application
    Filed: November 5, 2004
    Publication date: June 2, 2005
    Applicant: Sigma-Aldrich Co.
    Inventors: John Dapron, William Kappel, Handong Li