Patents by Inventor William Keating
William Keating has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240060132Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.Type: ApplicationFiled: February 13, 2023Publication date: February 22, 2024Inventors: James A. Garrett, Sha-Sha Wang, Keith Thornton, Richard L. Moore, William Keating, William A. Nussbaumer, Craig C. Whiteford
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Patent number: 11578367Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.Type: GrantFiled: October 8, 2019Date of Patent: February 14, 2023Assignee: Becton, Dickinson and CompanyInventors: James A. Garrett, Sha-Sha Wang, Keith Thornton, Richard L. Moore, William Keating, William A. Nussbaumer, Craig C. Whiteford
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Publication number: 20210087632Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.Type: ApplicationFiled: October 8, 2019Publication date: March 25, 2021Inventors: James A. Garrett, Sha-Sha Wang, Keith Thornton, Richard L. Moore, William Keating, William A. Nussbaumer, Craig C. Whiteford
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Patent number: 10562036Abstract: Various wear resistance designs may be applied to a reactor configured to facilitate chemical reactions, and/or comminution using shockwaves created in a supersonic gaseous vortex. The reactor may include a rigid chamber having a substantially circular cross-section. A first gas inlet may be configured to introduce a high-velocity gas stream into the chamber. A first replaceable wear part may be disposed in the chamber to absorb wear impact caused by the gas stream. In some implementations, the first replaceable wear part may be a cylindrical rod continuously fed into the chamber. In some implementations, the first replaceable wear part may be coated with, or composed of, a catalytic material, and/or may be electrically isolated from the rest of the reactor. In some implementations, a second gas inlet may be disposed to steer the gas stream to a desired area within the chamber to even out the wear impact.Type: GrantFiled: September 27, 2016Date of Patent: February 18, 2020Assignee: LLT International (Irelant) Ltd.Inventors: Peter Lansell, William Keating, David Lowe
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Patent number: 10443099Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.Type: GrantFiled: September 10, 2015Date of Patent: October 15, 2019Assignee: Becton, Dickinson and CompanyInventors: James A. Garrett, Sha-Sha Wang, Keith Thornton, Richard L. Moore, William Keating, William A. Nussbaumer, Craig C. Whiteford
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Patent number: 10434488Abstract: Methane may be dissociated at low temperatures and/or pressures utilizing a reactor designed to generate shockwaves in a supersonic gaseous vortex. Within a preprocessing chamber, the methane may be pressurized to a pressure of 700 kPa or more, and heated to a temperature below a dissociation temperature of methane. The methane may be introduced as a gas stream substantially tangentially to an inner surface of a chamber of the reactor to effectuate a gaseous vortex rotating about a longitudinal axis within the chamber. The gas stream may be introduced using a nozzle that accelerates the gas stream to a supersonic velocity. A frequency of shockwaves emitted from the nozzle into the gaseous vortex may be controlled. Product gas and carbon byproduct may be emitted from the chamber of the reactor. The carbon byproduct may be separated out from the product gas using a gas/solid separator.Type: GrantFiled: August 11, 2015Date of Patent: October 8, 2019Assignee: LLT INTERNATIONAL (IRELAND) LTD.Inventors: Peter Lansell, William Keating, David Lowe, Dominic Evans
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Patent number: 10427129Abstract: A gas reactor system may be configured for facilitating chemical reactions of gases using shockwaves produced in a supersonic gaseous vortex. The system may include a gas source to provide a gas to a heater and/or a reactor. The reactor may be configured to facilitate chemical reactions of gases using shockwaves created in a supersonic gaseous vortex. The reactor may be arranged with a gas inlet to introduce a high-velocity steam of gas into a chamber of the reactor. The gas inlet may effectuate a vortex of supersonic circulating gas within the chamber. The vortex may rotate at supersonic speed about the longitudinal axis of the chamber. The system may be configured to store an output product of the reactor in a storage tank in fluid communication with the reactor.Type: GrantFiled: April 17, 2015Date of Patent: October 1, 2019Assignee: LLT INTERNATIONAL (IRELAND) LTD.Inventors: Peter Lansell, William Keating, David Lowe
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Publication number: 20190070576Abstract: Various wear resistance designs may be applied to a reactor configured to facilitate chemical reactions, and/or comminution using shockwaves created in a supersonic gaseous vortex. The reactor may include a rigid chamber having a substantially circular cross-section. A first gas inlet may be configured to introduce a high-velocity gas stream into the chamber. A first replaceable wear part may be disposed in the chamber to absorb wear impact caused by the gas stream. In some implementations, the first replaceable wear part may be a cylindrical rod continuously fed into the chamber. In some implementations, the first replaceable wear part may be coated with, or composed of, a catalytic material, and/or may be electrically isolated from the rest of the reactor. In some implementations, a second gas inlet may be disposed to steer the gas stream to a desired area within the chamber to even out the wear impact.Type: ApplicationFiled: September 27, 2016Publication date: March 7, 2019Inventors: Peter LANSELL, William KEATING, David LOWE
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Patent number: 10137456Abstract: A reactor may be configured to facilitate chemical reactions and/or comminution of solid feed materials. The reactor may be configured to make use of shockwaves created in a supersonic gaseous vortex. The reactor may include a rigid chamber having a substantially circular cross-section. A gas inlet may be configured to introduce a high-velocity stream of gas into the chamber. The gas inlet may be disposed and arranged so as to effectuate a vortex of the stream of gas circulating within the chamber. The vortex may rotate at a supersonic speed about a longitudinal axis of the chamber. A material inlet may be configured to introduce a material to be processed into the chamber. The material may be processed within the chamber by nonabrasive mechanisms facilitated by shockwaves within the chamber. An outlet may be configured to emit the gas and processed material from the chamber.Type: GrantFiled: May 21, 2015Date of Patent: November 27, 2018Assignee: LLT International (Ireland) Ltd.Inventors: Peter Lansell, William Keating, David Lowe
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Patent number: 9724703Abstract: Solid materials may be processed using shockwaves produced in a supersonic gaseous vortex. A high-velocity stream of gas may be introduced into a reactor. The reactor may have a chamber, a solid material inlet, a gas inlet, and an outlet. The high-velocity stream of gas may be introduced into the chamber of the reactor through the gas inlet. The high-velocity stream of gas may effectuate a supersonic gaseous vortex within the chamber. The reactor may be configured to facilitate chemical reactions and/or comminution of solid feed material using tensive forces of shockwaves created in the supersonic gaseous vortex within the chamber. Solid material may be fed into the chamber through the solid material inlet. The solid material may be processed within the chamber by nonabrasive mechanisms facilitated by the shockwaves within the chamber. The processed material that is communicated through the outlet of the reactor may be collected.Type: GrantFiled: June 6, 2014Date of Patent: August 8, 2017Assignee: LLT International (Ireland) Ltd.Inventors: Peter Lansell, William Keating, David Lowe
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Publication number: 20170043315Abstract: Methane may be dissociated at low temperatures and/or pressures utilizing a reactor designed to generate shockwaves in a supersonic gaseous vortex. Within a preprocessing chamber, the methane may be pressurized to a pressure of 700 kPa or more, and heated to a temperature below a dissociation temperature of methane. The methane may be introduced as a gas stream substantially tangentially to an inner surface of a chamber of the reactor to effectuate a gaseous vortex rotating about a longitudinal axis within the chamber. The gas stream may be introduced using a nozzle that accelerates the gas stream to a supersonic velocity. A frequency of shockwaves emitted from the nozzle into the gaseous vortex may be controlled. Product gas and carbon byproduct may be emitted from the chamber of the reactor. The carbon byproduct may be separated out from the product gas using a gas/solid separator.Type: ApplicationFiled: August 11, 2015Publication date: February 16, 2017Inventors: Peter LANSELL, William KEATING, David LOWE, Dominic EVANS
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Publication number: 20160303539Abstract: A gas reactor system may be configured for facilitating chemical reactions of gases using shockwaves produced in a supersonic gaseous vortex. The system may include a gas source to provide a gas to a heater and/or a reactor. The reactor may be configured to facilitate chemical reactions of gases using shockwaves created in a supersonic gaseous vortex. The reactor may be arranged with a gas inlet to introduce a high-velocity steam of gas into a chamber of the reactor. The gas inlet may effectuate a vortex of supersonic circulating gas within the chamber. The vortex may rotate at supersonic speed about the longitudinal axis of the chamber. The system may be configured to store an output product of the reactor in a storage tank in fluid communication with the reactor.Type: ApplicationFiled: April 17, 2015Publication date: October 20, 2016Inventors: Peter LANSELL, William KEATING, David LOWE
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Publication number: 20160303577Abstract: Various wear resistance designs may be applied to a reactor configured to facilitate chemical reactions, and/or comminution using shockwaves created in a supersonic gaseous vortex. The reactor may include a rigid chamber having a substantially circular cross-section. A first gas inlet may be configured to introduce a high-velocity gas stream into the chamber. A first replaceable wear part may be disposed in the chamber to absorb wear impact caused by the gas stream. In some implementations, the first replaceable wear part may be a cylindrical rod continuously fed into the chamber. In some implementations, the first replaceable wear part may be coated with, or composed of, a catalytic material, and/or may be electrically isolated from the rest of the reactor. In some implementations, a second gas inlet may be disposed to steer the gas stream to a desired area within the chamber to even out the wear impact.Type: ApplicationFiled: April 17, 2015Publication date: October 20, 2016Inventors: Peter LANSELL, William KEATING, David LOWE
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Patent number: 9452434Abstract: Various wear resistance designs may be applied to a reactor configured to facilitate chemical reactions, and/or comminution using shockwaves created in a supersonic gaseous vortex. The reactor may include a rigid chamber having a substantially circular cross-section. A first gas inlet may be configured to introduce a high-velocity gas stream into the chamber. A first replaceable wear part may be disposed in the chamber to absorb wear impact caused by the gas stream. In some implementations, the first replaceable wear part may be a cylindrical rod continuously fed into the chamber. In some implementations, the first replaceable wear part may be coated with, or composed of, a catalytic material, and/or may be electrically isolated from the rest of the reactor. In some implementations, a second gas inlet may be disposed to steer the gas stream to a desired area within the chamber to even out the wear impact.Type: GrantFiled: April 17, 2015Date of Patent: September 27, 2016Assignee: LLT International (Ireland) Ltd.Inventors: Peter Lansell, William Keating, David Lowe
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Publication number: 20160168638Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.Type: ApplicationFiled: September 10, 2015Publication date: June 16, 2016Inventors: James A. Garrett, Sha-Sha Wang, Keith Thornton, Richard L. Moore, William Keating, William A. Nussbaumer, Craig C. Whiteford
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Publication number: 20150352558Abstract: Solid materials may be processed using shockwaves produced in a supersonic gaseous vortex. A high-velocity stream of gas may be introduced into a reactor. The reactor may have a chamber, a solid material inlet, a gas inlet, and an outlet. The high-velocity stream of gas may be introduced into the chamber of the reactor through the gas inlet. The high-velocity stream of gas may effectuate a supersonic gaseous vortex within the chamber. The reactor may be configured to facilitate chemical reactions and/or comminution of solid feed material using tensive forces of shockwaves created in the supersonic gaseous vortex within the chamber. Solid material may be fed into the chamber through the solid material inlet. The solid material may be processed within the chamber by nonabrasive mechanisms facilitated by the shockwaves within the chamber. The processed material that is communicated through the outlet of the reactor may be collected.Type: ApplicationFiled: June 6, 2014Publication date: December 10, 2015Applicant: LLT International (Ireland) Ltd.Inventors: Peter Lansell, William Keating, David Lowe
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Patent number: 9050604Abstract: A reactor may be configured to facilitate chemical reactions and/or comminution of solid feed materials. The reactor may be configured to make use of shockwaves created in a supersonic gaseous vortex. The reactor may include a rigid chamber having a substantially circular cross-section. A gas inlet may be configured to introduce a high-velocity stream of gas into the chamber. The gas inlet may be disposed and arranged so as to effectuate a vortex of the stream of gas circulating within the chamber. The vortex may rotate at a supersonic speed about a longitudinal axis of the chamber. A material inlet may be configured to introduce a material to be processed into the chamber. The material may be processed within the chamber by nonabrasive mechanisms facilitated by shockwaves within the chamber. An outlet may be configured to emit the gas and processed material from the chamber.Type: GrantFiled: June 6, 2014Date of Patent: June 9, 2015Assignee: LLT International (Ireland) Ltd.Inventors: Peter Lansell, William Keating, David Lowe
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Publication number: 20140141435Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.Type: ApplicationFiled: August 12, 2013Publication date: May 22, 2014Applicant: Beckton, Dickinson and CompanyInventors: James A. Garrett, Sha-Sha Wang, Keith Thornton, Richard L. Moore, William Keating, William A. Nussbaumer, Craig C. Whiteford
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Publication number: 20110105350Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.Type: ApplicationFiled: May 7, 2010Publication date: May 5, 2011Inventors: James A. Garrett, Sha-Sha Wang, Keith Thornton, Richard L. Moore, William Keating, William A. Nussbaumer, Craig C. Whiteford
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Patent number: 7767395Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.Type: GrantFiled: April 14, 2006Date of Patent: August 3, 2010Assignee: Becton, Dickinson and CompanyInventors: James A. Garrett, Sha-Sha Wang, Keith Thornton, Richard L. Moore, William Keating, William A. Nussbaumer, Craig C. Whiteford