Abstract: The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis.

Abstract: An aortic stent-graft may include a tubular graft extending from a proximal end to a distal end, the graft comprising a proximal sealing portion and an intermediate portion, wherein a proximal end of the intermediate portion abuts the distal end of the proximal sealing portion. At least one sealing stent may be attached to the proximal sealing portion. A first fenestration window is disposed in the intermediate portion. The first fenestration window has a length determined by the equation L=1.23*D?24 millimeters, where L is the length of the first fenestration window. D is between about 24 millimeters and 45 millimeters.

Abstract: A delivery system may include a stent-graft, a locking member, and one or more diameter reducing members. The stent-graft may include a tubular graft comprising first and second longitudinally extending sides disposed opposite each other and connected at a tangent line. When the locking member is in a locked position, the locking member restrains a surface of the graft against the cannula. The first diameter reducing member may be slidably connected to a first portion of the graft that is disposed proximate the tangent line and may be slidably connected to a second portion of the graft that is spaced circumferentially away from the tangent line. When the first diameter reducing member is in a restrained position, the second portion of the graft is drawn toward the first portion of the graft and the proximal portion of the stent-graft has a reduced diameter configuration with at least two lobes.

Abstract: A method of forming a surface structure of a component of a medical devices includes forming a fatigue-resistant portion, which entails forming a first layer comprising a transition metal selected from the group consisting of Ta, Nb, Mo, V, Mn, Fe, Cr, Co, Ni, Cu, and Si on at least a portion of a surface of the component, where the surface comprises a nickel-titanium alloy, and alloying the transition metal of the first layer with the nickel-titanium alloy of the surface. The method further includes forming a rough outer surface of the fatigue-resistant portion where the rough outer surface is adapted for adhesion of a material thereto.

Abstract: A woven fabric for a low profile implantable medical device includes a plurality of textile strands of a composite yarn aligned in a first direction interlaced with a plurality of textile strands of the composite yarn aligned in a second direction. The composite yarn includes a combination of a first material and a second material. The textile strands have a size between about 10 denier to about 20 denier. The first material has at least one characteristic different from the second material and the second material reacts favorably with blood when placed within an artery.

Abstract: A dilator tip (100) for deploying and positioning an endovascular device (570) at a treatment site includes an elongate body (105) having at least two substantially longitudinal channels (110) in an outer surface (105s) of the body and at least two deployment struts (115). Each deployment strut (115) has a free end (120) releasably attached to a proximal edge (575) of an endovascular device (570) to be deployed, a constrained end (125) restrained within one of the longitudinal channels (110), and a pivot portion (130) between the free end (120) and the constrained end (125). In an undeployed configuration of the dilator tip (100), the free ends (120) reside within the longitudinal channels (110), and in a deployed configuration of the dilator tip (100), the free ends (120) are pivotally extended away from the longitudinal channels (110) by way of the pivot portions (130).

Abstract: An endoluminal prosthesis includes a support structure including a curvilinear portion having a first strut and a second strut that meet at an apex. Disposed on the support structure is an anchor with an anchor body and one or more barbs extending outwardly from the anchor body. The anchor body can fit at least partially about, and can conform to the first strut, second strut, and the apex. A curved portion of the anchor and the curvilinear portion of the support structure can be co-formed, resulting in a secure interference fit so that welding, soldering, or other joining mechanisms can be avoided. Cutouts can be formed along the curved portion of the anchor to relieve stress or strain during the co-forming process.

Abstract: An implantable medical device includes a carrier element having a distal holding member (60) which includes a proximal connecting element (64) which is attached to a guidewire catheter (24) and a distal connecting element (68) which is attached to a dilator tip (20). A proximal connecting element (64) includes a plurality of ribs (74) which have a perpendicular shoulder (80) spaced from an enlarged head (82). The shoulder (80) supports and endmost stent (92) of a device held by the distal holding member (60). Guide wires (98) pass through lumens (86, 88) in the ribs (74) and enlarged head (82), these guidewires (98) being substantially straight. The ribs (74) support an implantable medical device both in the longitudinal direction and in the radial direction. The device (90) can also be pulled rather than pushed by means of the introducer assembly.

Abstract: An aortic stent-graft may include a tubular graft extending from a proximal end to a distal end, the graft comprising a proximal sealing portion and an intermediate portion, wherein a proximal end of the intermediate portion abuts the distal end of the proximal sealing portion. At least one sealing stent may be attached to the proximal sealing portion. A first fenestration window is disposed in the intermediate portion. The first fenestration window has a length determined by the equation L=1.23*D?24 millimeters, where L is the length of the first fenestration window. D is between about 24 millimeters and 45 millimeters.

Abstract: The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis.

Abstract: An endoluminal prosthesis includes a support structure including a curvilinear portion having a first strut and a second strut that meet at an apex. Disposed on the support structure is an anchor with an anchor body and one or more barbs extending outwardly from the anchor body. The anchor body can fit at least partially about, and can conform to the first strut, second strut, and the apex. A curved portion of the anchor and the curvilinear portion of the support structure can be co-formed, resulting in a secure interference fit so that welding, soldering, or other joining mechanisms can be avoided. Cutouts can be formed along the curved portion of the anchor to relieve stress or strain during the co-forming process.

Abstract: A composite woven fabric for a low profile implantable medical device having a plurality of textile strands of a first material aligned in a first direction interlaced with a plurality of textile strands of a second material. The textile strands have a size between about 10 denier to about 20 denier. The first material has at least one characteristic different from the second material and the second material reacts more favorably with blood when placed within an artery.

Abstract: A woven fabric for a low profile implantable medical device includes a plurality of textile strands of a composite yarn aligned in a first direction interlaced with a plurality of textile strands of the composite yarn aligned in a second direction. The composite yarn includes a combination of a first material and a second material. The textile strands have a size between about 10 denier to about 20 denier. The first material has at least one characteristic different from the second material and the second material reacts favorably with blood when placed within an artery.

Abstract: A delivery system may include a stent-graft, a locking member, and one or more diameter reducing members. The stent-graft may include a tubular graft comprising first and second longitudinally extending sides disposed opposite each other and connected at a tangent line. When the locking member is in a locked position, the locking member restrains a surface of the graft against the cannula. The first diameter reducing member may be slidably connected to a first portion of the graft that is disposed proximate the tangent line and may be slidably connected to a second portion of the graft that is spaced circumferentially away from the tangent line. When the first diameter reducing member is in a restrained position, the second portion of the graft is drawn toward the first portion of the graft and the proximal portion of the stent-graft has a reduced diameter configuration with at least two lobes.

Abstract: A dilator tip (100) for deploying and positioning an endovascular device (570) at a treatment site includes an elongate body (105) having at least two substantially longitudinal channels (110) in an outer surface (105s) of the body and at least two deployment struts (115). Each deployment strut (115) has a free end (120) releasably attached to a proximal edge (575) of an endovascular device (570) to be deployed, a constrained end (125) restrained within one of the longitudinal channels (110), and a pivot portion (130) between the free end (120) and the constrained end (125). In an undeployed configuration of the dilator tip (100), the free ends (120) reside within the longitudinal channels (110), and in a deployed configuration of the dilator tip (100), the free ends (120) are pivotally extended away from the longitudinal channels (110) by way of the pivot portions (130).

Abstract: The disclosure relates to an intraluminal medical device. The medical device comprises a main graft, a first extension graft, and a second extension graft. The main graft comprises a proximal end, a distal end, and a body extending between the proximal end and distal end. The distal end of the main graft comprises a first branch and a second branch, the branches extending distally from the body. The first and second extension grafts comprise at least one stent and have a body reinforcing portion and a branch reinforcing portion. The body reinforcing portions have a larger expanded dimension than the expanded dimension of the respective branch reinforcing portion. The body reinforcing portions, together, have an expanded dimension that is generally equal to the expanded dimension of the outer graft body.

Abstract: The disclosure relates to an intraluminal medical device. The medical device comprises a main graft, a first extension graft, and a second extension graft. The main graft comprises a proximal end, a distal end, and a body extending between the proximal end and distal end. The distal end of the main graft comprises a first branch and a second branch, the branches extending distally from the body. The first and second extension grafts comprise at least one stent and have a body reinforcing portion and a branch reinforcing portion. The body reinforcing portions have a larger expanded dimension than the expanded dimension of the respective branch reinforcing portion. The body reinforcing portions, together, have an expanded dimension that is generally equal to the expanded dimension of the outer graft body.

Abstract: An implantable device having a composite weave graft is disclosed. The device comprises a graft body forming a lumen defining a longitudinal axis and comprising proximal and distal ends. The graft body comprises a composite of low dernier yarns and polymeric yarns configured for low profile delivery and radial elongation relative to the longitudinal axis during use. The graft body has a first portion and a second portion extending from the first portion. The first portion comprises at least one expandable stent radially attached thereto for support and the second portion having corrugations for enhanced kink resistance.