Patents by Inventor William L. O'Brien

William L. O'Brien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240139512
    Abstract: An example system includes a first lead configured to be positioned in or beside a left internal jugular vein (IJV) of a patient to deliver a first stimulation signal to a first vagus nerve, the first lead including one or more first segmented electrodes positioned on a distal portion of the first lead and a first anchoring mechanism; a second lead configured to be positioned in or beside a right IJV of the patient to deliver a second stimulation signal to a second vagus nerve, the second lead including one or more second segmented electrodes positioned on a distal portion of the second lead and a second anchoring mechanism; and circuitry configured to deliver electrical energy to the first lead to deliver the first stimulation signal and the second lead to deliver the second stimulation signal to provide bilateral stimulation to the first vagus nerve and the second vagus nerve.
    Type: Application
    Filed: October 28, 2022
    Publication date: May 2, 2024
    Inventors: Randal C. Schulhauser, Richard J. O'Brien, Scott R. Stanslaski, Mark P. Ashby, Avram Scheiner, Becky L. Dolan, William Valls, JR., David J. Miller, Varun Umesh Kashyap, Peter N. Braido, Lilian Kornet
  • Patent number: 6072022
    Abstract: A polyester composition for use in facilitating separation of blood serum or plasma from a cellular portion of blood, the composition containing: (a) a multifunctional acid component comprising: (i) a benzene polycarboxylic acid, and derivatives thereof; and (ii) an aliphatic polycarboxylic acid having from about 16 to about 40 carbon atoms; and (b) a diol component, and wherein the multifunctional acid component and diol component are employed in an equivalent ratio ranging from about 0.8:1.1 to about 1.0:1.3.
    Type: Grant
    Filed: November 3, 1999
    Date of Patent: June 6, 2000
    Assignee: Henkel Corporation
    Inventors: William L. O'Brien, Dean A. Oester, Jeffrey A. Barnhorst, Lidia Kupczyk-Subotkowska, John P. Fisher
  • Patent number: 5986039
    Abstract: Polyesters are described which are substantially the condensation products of at least one dicarboxylic acid, at least one volatile diol and at least one hydroxyl-functional component with functionality greater than 2 which controls ultimate viscosity. The products are suitable vehicles for the formulated thixotropic gels for centrifugal separation of fluids such as serum into high and low density components of, for example, separation of mixtures of cells on the basis of density.
    Type: Grant
    Filed: October 16, 1997
    Date of Patent: November 16, 1999
    Assignee: Henkel Corporation
    Inventors: William L. O'Brien, Alan C. Kilbarger
  • Patent number: 5731391
    Abstract: A fluid which comprises an olefin-terminated polyester an unmodified polyester and a polymerized .alpha.-olefin is provided which facilitates the separation of blood into light and heavy phases via centrifugation in a blood collection vessel. The fluid is useful as a component of a partitioning composition formulated to have appropriate specific gravity to be positioned intermediate the light and heavy blood phases during centrifugation. A partitioning composition including a fluid of the invention provides a particular advantage in blood collection vessels used in therapeutic drug monitoring, due to the relatively low affinity between the fluid component of the composition and commonly monitored classes of drugs.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: March 24, 1998
    Assignee: Henkel Corporation
    Inventors: William L. O'Brien, Alan C. Kilbarger
  • Patent number: 5576367
    Abstract: Liquid polyester plasticizers, having a hydroxyl value of at least 25, are incorporated into vinyl resins, such as PVC, which are formed into gaskets for use on appliances made from textured coil stock, especially refrigerators or freezers. These plasticizers have no detrimental effect on the relatively soft surface coatings on such appliances.
    Type: Grant
    Filed: January 3, 1990
    Date of Patent: November 19, 1996
    Assignee: Henkel Corporation
    Inventors: William L. O'Brien, William J. Mertz
  • Patent number: 5556557
    Abstract: A polyester is provided which facilitates the separation of blood into light and heavy phases via centrifugation in a blood collection vessel. The polyester is useful as a component of a partitioning composition formulated to have appropriate specific gravity to be positioned intermediate the light and heavy blood phases during centrifugation. A partitioning composition including a polyester of the invention provides a particular advantage in blood collection vessels due to its lighter and more consistent coloration. The polyester composition can be prepared with relative ease compared to prior art polyesters useful in blood partitioning compositions.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 17, 1996
    Assignee: Henkel Corporation
    Inventors: William L. O'Brien, Alan C. Kilbarger
  • Patent number: 5506333
    Abstract: A polyester is provided which facilitates the separation of blood into light and heavy phases via centrifugation in a blood collection vessel. The polyester is useful as a component of a partitioning composition formulated to have appropriate specific gravity to be positioned intermediate the light and heavy blood phases during centrifugation. A partitioning composition including a polyester of the invention provides a particular advantage in blood collection vessels due to its lighter and more consistent coloration. The polyester composition can be prepared with relative ease compared to prior art polyesters useful in blood partitioning compositions.
    Type: Grant
    Filed: February 16, 1995
    Date of Patent: April 9, 1996
    Assignee: Henkel Corporation
    Inventors: William L. O'Brien, Alan C. Kilbarger
  • Patent number: 5124434
    Abstract: A polyester is provided which facilitates the separation of blood into light and heavy phases via centrifugation in a blood collection vessel. The polyester is useful as a component of a partitioning composition formulated to have appropriate specific gravity to be positioned intermediate the light and heavy blood phases during centrifugation. A partitioning composition including a polyester of the invention provides a particular advantage in blood collection vessels used in therapeutic drug monitoring, due to the relatively low affinity between the polyester component of the composition and commonly monitored classes of drugs.
    Type: Grant
    Filed: August 15, 1991
    Date of Patent: June 23, 1992
    Assignee: Henkel Corporation
    Inventor: William L. O'Brien
  • Patent number: 4698383
    Abstract: Liquid copolyesters useful as plasticizers for vinyl resins are provided. The copolyesters are obtained by the esterification of specific aliphatic dicarboxylic acid ester mixtures with 1,4-butanediol and an aliphatic saturated monofunctional alcohol. The copolyesters have acceptably low solidification points; they are resistant to hydrocarbon extraction; and they impart good low-temperature flexibility to PVC compositions plasticized therewith.
    Type: Grant
    Filed: March 9, 1987
    Date of Patent: October 6, 1987
    Assignee: National Distillers and Chemical Corporation
    Inventors: William J. Mertz, William L. O'Brien
  • Patent number: 4689429
    Abstract: Liquid copolyesters useful as plasticizers for vinyl resins are provided. The copolyesters are obtained by the esterification of specific aliphatic dicarboxylic acid ester mixtures with 1,4-butanediol and an aliphatic saturated monofunctional alcohol. The copolyesters have acceptably low solidification points; they are resistant to hydrocarbon extraction; and they impart good low-temperature flexibility to PVC compositions plasticized therewith.
    Type: Grant
    Filed: August 7, 1986
    Date of Patent: August 25, 1987
    Assignee: National Distillers and Chemical Corporation
    Inventors: William J. Mertz, William L. O'Brien
  • Patent number: 4103617
    Abstract: In impact printing mechanism for encoding magnetic or optical characters on documents, a hammer energy control is utilized for maintaining constant impact pressure for the various surface areas of such characters. The constant impact pressure is derived by selection of the correct hammer pulse width for the surface area of each character.
    Type: Grant
    Filed: January 10, 1977
    Date of Patent: August 1, 1978
    Assignee: NCR Canada Ltd. - NCR Canada Ltee
    Inventors: William L. O'Brien, Wayne M. Doran
  • Patent number: 4066587
    Abstract: The flow characteristics and rheological properties of thermoplastic polyesters and copolyesters are significantly improved by the addition of a polyamide resin thereto. In addition to improving the processability of the thermoplastic materials the polymeric additives also impart other desirable properties to the resulting manufactured products.
    Type: Grant
    Filed: September 7, 1976
    Date of Patent: January 3, 1978
    Assignee: Emery Industries, Inc.
    Inventors: Harold E. Mains, Frederick R. Williams, William L. O'Brien
  • Patent number: 4062819
    Abstract: The flow characteristics and rheological properties of high molecular weight thermoplastic polyamides are significantly improved by blending therewith a small amount of a polyamide derived from high molecular weight dibasic acids. In addition to improving the processability of the thermoplastic resin, the blends and manufactured articles produced therefrom have other desirable properties.
    Type: Grant
    Filed: September 7, 1976
    Date of Patent: December 13, 1977
    Assignee: Emery Industries, Inc.
    Inventors: Harold E. Mains, Frederick R. Williams, William L. O'Brien
  • Patent number: 4062829
    Abstract: Polyester compositions containing organophosphorus derivatives as stabilizers are disclosed. Methods of stabilizing polyesters are also provided by incorporating the organophosphorus derivatives during processing to prevent thermal and catalytic decomposition, and with improvements in resin color, molecular weight retention and mechanical properties. This invention also affords an efficient method of inhibiting the decomposition activity of the first stage catalyst in the production of high polymeric condensation polyester resins.
    Type: Grant
    Filed: November 8, 1976
    Date of Patent: December 13, 1977
    Assignee: Emery Industries, Inc.
    Inventor: William L. O'Brien
  • Patent number: 4043981
    Abstract: Flame retardant high molecular weight linear copolyesters capable of being formed into fibers and filaments and which exhibit a high degree of thermal and ultraviolet stability are obtained using ethoxylated 3,5-dibromo-4-hydroxybenzoic acid.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: August 23, 1977
    Assignee: Emery Industries, Inc.
    Inventor: William L. O'Brien