Abstract: There are provided in accordance with the present invention crystalline gatifloxacin pentahydrate represented by the formula in a highly homogeneous form with respect to other crystalline forms thereof.

Abstract: There are provided in accordance with the present invention crystalline gatifloxacin pentahydrate represented by the formula 1

Abstract: Cultivation of a strain of the microorganism Micromonospora sp. A.T.C.C. No. 53481, yields the novel antibiotic substance glyphomicin, which is a mixture of glyphomicin A and glyphomicin B.

Abstract: Antibacterial activity is exhibited by .beta.-lactams having a sulfonic acid salt substituent in the 1-position and an amino or acylamino substituent in the 3-position.

Abstract: Aerocavin, a novel antibiotic substance having the structure ##STR1## and aerocyanidin, a novel antibiotic substance having the structure ##STR2## can be prepared by cultivation of the microorganism Aerocavin caviae SC 14,030 A.T.C.C. No. 53434.

Abstract: A method and apparatus for restoring a beach by raising the level of the beach between the high tide line and the low tide line of the beach in which an elongated rectangular net of nylon cord is suspended from a temporary supporting structure generally perpendicular to the high tide line of the beach and extending from the high tide line to at least the low tide line, said net having a uniform mesh sized to prohibit passage through said net of the larger rocks, coral and shells present on the sea floor and having a weighted bottom edge resting upon the sea floor and a top edge suspended above the high tide level of the sea, wherein said net remains suspended between the high tide line and the low tide line for a period of at least twelve hours, and then said net and its supporting structure are removed from the beach.

Abstract: Aerocavin, a novel antibiotic substance having the structure ##STR1## and aerocyanidin, a novel antibiotic substance having the structure ##STR2## can be prepared by cultivation of the microorganism Aerocavin caviae SC 14,030 A.T.C.C. No. 53434.

Abstract: A pharmaceutically acceptable salt of (R)-3-(acetylamino)-3-methoxy-2-oxo-1-azetidinesulfonic acid can be prepared by culturing Chromobacterium violaceum A.T.C.C. No. 31532 at about 25.degree. C. under submerged aerobic conditions on an aqueous nutrient medium containing an assimilable carbohydrate and nitrogen source.

Abstract: Cultivation of a strain of the microorganism Pseudomonas cepacia SC 11,783, A.T.C.C. No. 39356 yields a novel antibiotic substance which is made up of two compounds, i.e., 5-[3-[3-(hepta-1,2-dien-4,6-diynyl)oxiran-2-yl]-3-hydroxy-1-propanyl]dihyd ro-2(3H)-furanone and 5-[[3-[3-(hepta-1,2-dien-4,6-diynyl)-2-oxiranyl]-2-oxiranyl]hydroxymethyl] dihydro-2(3H)-furanone.

Abstract: Culturing aerobically Serratia sp. SC 11,482 A.T.C.C. No. 39006 in a culture medium containing assimilable carbon and nitrogen sources yields 1-carba-2-penem-3-carboxylic acid.

Abstract: Culturing aerobically Agrobacterium radiobacter no. 31700 in a culture medium containing carbon and nitrogen sources yields the antibiotic substance EM5400, comprising salts of certain azetidinesulfonic acid derivatives.

Abstract: A mixture of antibiotic substances designated polymyxin F is obtained by the cultivation under controlled conditions of a strain of Bacillus circulans, and is active against gram-negative and gram-positive bacteria. This strain of Bacillus circulans has been deposited in the American Type Culture Collection as A.T.C.C. No. 31228.