Patents by Inventor William L. Stanley

William L. Stanley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4167447
    Abstract: Insolubilized but active enzymes are prepared in a variety of ways. In one embodiment of the invention an aqueous solution of an enzyme is mixed with chitosan dissolved in water at pH 3-7 and an insolubilized product is precipitated therefrom by addition of alkali or a source of sulfate ions. Another embodiment of the invention involves contacting solid chitosan sulfate with an aqueous solution of the enzyme to be immobilized. In yet another embodiment of the invention solid chitosan is cross-linked with a polyfunctional cross-linking agent and then contacted with an aqueous solution of an enzyme. Enzymes insolubilized in accordance with the invention retain a substantial part of their original activity.
    Type: Grant
    Filed: March 24, 1978
    Date of Patent: September 11, 1979
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Merle S. Masri, Virginia G. Randall, William L. Stanley
  • Patent number: 4113567
    Abstract: Insolubilized but active enzymes are prepared by mixing an aqueous solution of the enzyme with a modified phenolic polymer. The phenolic polymer is modified by introducing into the polymer chain either aldehyde groups or diazonium salt groups. The so-produced enzyme products retain a substantial part of the original enzyme activity.
    Type: Grant
    Filed: August 25, 1977
    Date of Patent: September 12, 1978
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Merle S. Masri, Virginia G. Randall, William L. Stanley
  • Patent number: 4089746
    Abstract: Insolubilized but active enzymes are prepared by mixing an aqueous solution of the enzyme with an aqueous solution of chitosan and then adding a polyfunctional cross-linking agent to form a gel. The so-produced gel is reacted with a reducing agent to form a granular insolubilized enzyme, which has retained a substantial part of its original activity.
    Type: Grant
    Filed: July 19, 1976
    Date of Patent: May 16, 1978
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Merle S. Masri, Virginia G. Randall, William L. Stanley
  • Patent number: 4069106
    Abstract: Insolubilized but active enzymes are prepared by mixing an aqueous solution of the enzyme with reduced keratin-containing material. The invention is particularly useful for insolubilizing sulfhydryl-containing enzymes such as urease.
    Type: Grant
    Filed: January 13, 1977
    Date of Patent: January 17, 1978
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: William L. Stanley, Glenn G. Watters, Bock G. Chan
  • Patent number: 3972918
    Abstract: Tyrosine and 3,4-dihydroxyphenylalanine (DOPA) are separated from a mixture thereof by applying the mixture to a polymer of p-vinylbenzene boronic acid, and then serially eluting the tyrosine and DOPA.
    Type: Grant
    Filed: June 28, 1974
    Date of Patent: August 3, 1976
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: William L. Stanley, Carl A. Elliger, Bock G. Chan
  • Patent number: 3951820
    Abstract: Substances which are subject to microbial spoilage are preserved by addition of a cinnamyl phenol, e.g., 2-cinnamyl-phenol, 4-cinnamyl-phenol, 2-methoxy-4-cinnamyl-phenol, 2-cinnamyl-5-methoxy-quinol, etc.
    Type: Grant
    Filed: February 21, 1973
    Date of Patent: April 20, 1976
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Leonard Jurd, A. Douglas King, Jr., William L. Stanley
  • Patent number: 3936393
    Abstract: Substances which are subject to microbial spoilage are preserved by addition of a cinnamyl phenol, e.g., 2-cinnamylphenol, 4-cinnamyl phenol, 2-methoxy-4-cinnamyl-phenol, 2-cinnamyl-5-methoxy-quinol, etc.
    Type: Grant
    Filed: April 17, 1973
    Date of Patent: February 3, 1976
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Leonard Jurd, A. Douglas King, Jr., William L. Stanley