Abstract: The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.

Abstract: An edge seal for sealing an outer surface of a lower electrode assembly configured to support a semiconductor substrate in a plasma processing chamber, the lower electrode assembly including an annular groove defined between a lower member and an upper member of the lower electrode assembly. The edge seal includes an elastomeric band configured to be arranged within the groove, the elastomeric band having an annular upper surface, an annular lower surface, an inner surface, and an outer surface. When the elastomeric band is in an uncompressed state, the outer surface of the elastomeric band is concave. When the upper and lower surfaces are axially compressed at least 1% such that the elastomeric band is in a compressed state, an outward bulging of the outer surface is not greater than a predetermined distance. The predetermined distance corresponds to a maximum outer diameter of the elastomeric band in the uncompressed state.

Abstract: Training sets of images used for training machine vision systems for object recognition may be augmented via various training set augmentation methods. The machine vision systems trained via the augmented training sets may be further used in an augmented reality procedural guidance system for guiding an operator to complete one or more steps with respect to one or more objects. The training set augmentations may include one or more of an object motion augmentation, a camera motion augmentation, an object herding or clumping augmentation, an object size reduction augmentation, a diversified background augmentation, and a diversified background augmentation with synthetic background images. In some instances, machine vision systems may also be alternatively or concurrently trained to use optically distinguishable markers to recognize objects.

Abstract: The present disclosure provides a surgical shunt assembly tool that provides a more efficacious grip on the catheter tubes and prevent the tip of the catheter from buckling while the catheter is pushed onto the tip of the valve during installation of shunts during CSF shunt surgery. The tool includes standard handles such as used in a shodded mosquito tool having a clamping jaw integrated into the distal end section of the handle. The distal jaw includes two forcep jaw sections each having a proximal end integrally formed with a distal end of a distal end arm section of one of the two handle arms, and a distal end section extending away from the distal end arm section. The distal end sections of the forcep jaw sections are cylindrically shaped such that when the forcep jaw is closed by bringing the two forcep jaw sections together, a cylinder is formed having a diameter substantially equal to a diameter of a catheter tube to be attached to a shunt valve tip.

Abstract: A system, method, and computer readable medium includes obtaining activities of members of the online social networking system and social graph data of the members and computing an influence score for one of the members by combing an access to content score with an activities score. The access to content score is based on a number of social graph connections of the one of the members with other members and the activities score is based on a number of activities by the member with content items posted to the online social networking system by other members and activities by other members with content items posted by the member. A user interface displays a user interface screen to display the influence score in relation to the member and, in response to a selection, displays an influence score calculation screen including graphical illustrations of the access to content and activities scores.

Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably osculating at least a portion of a subject's ocular globe while applying a force sufficient to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, such as retinal, corneal, and pupil imaging. The components may include an optical contact surface that has a radius of curvature that is greater than the radius of curvature of a subject's cornea.

Abstract: A method for detecting stick-slip in a drillstring includes (a) measuring a parameter that is a function of a torque applied to the drillstring by a top drive system over a selected time period, the measuring being performed by at least one surface sensor that produces measurement data including torque values over a frequency range; (b) filtering out measurement data that has a frequency outside a selected frequency band, the selected frequency band including a resonant frequency of the drillstring; (c) identifying a minimum and a maximum torque value in the filtered measurement data and determining a difference of these two values; (d) determining a surface stick-slip index by dividing the difference of the maximum and minimum torque values by an average torque value over the selected time period; and (e) displaying the surface stick-slip index on a display.

Abstract: A film, coating, appliqué and method to eliminate paint removal via hazardous methods and maintain effective corrosion inhibition via employment of a re-useable coating. Embodiments of the invention generally relate to a multilayer film having a first layer constructed of at least one electro-active polymer, a second layer constructed of at least one flexible electrically-conductive solid, and a third layer constructed of at least one inert polymer.

Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably osculating at least a portion of a subject's ocular globe while applying a force sufficient to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, such as retinal, corneal, and pupil imaging. The components may include an optical contact surface that has a radius of curvature that is greater than the radius of curvature of a subject's cornea.

Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably osculating at least a portion of a subject's ocular globe while applying a force sufficient to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, such as retinal, corneal, and pupil imaging. The components may include an optical contact surface that has a radius of curvature that is greater than the radius of curvature of a subject's cornea.

Abstract: Provided are methods for noninvasively assessing intracranial pressure (“ICP”) based on optic nerve sheath diameter (“ONSD”) and a blood velocity metric, such as pulsatility or resistivity index. Also provided are related devices and systems for performing the claimed methods.

Abstract: A method for detecting stick-slip in a drillstring includes (a) measuring a parameter that is a function of a torque applied to the drillstring by a top drive system over a selected time period, the measuring being performed by at least one surface sensor that produces measurement data including torque values over a frequency range; (b) filtering out measurement data that has a frequency outside a selected frequency band, the selected frequency band including a resonant frequency of the drillstring; (c) identifying a minimum and a maximum torque value in the filtered measurement data and determining a difference of these two values; (d) determining a surface stick-slip index by dividing the difference of the maximum and minimum torque values by an average torque value over the selected time period; and (e) displaying the surface stick-slip index on a display.

Abstract: A film, coating, appliqué and method to eliminate paint removal via hazardous methods and maintain effective corrosion inhibition via employment of a re-useable coating. Embodiments of the invention generally relate to a multilayer film having a first layer constructed of at least one electro-active polymer, a second layer constructed of at least one flexible electrically-conductive solid, and a third layer constructed of at least one inert polymer.

Abstract: A method to generate renewable high performance composites and thermoplastics. These materials can be generated from a renewable phenol (syringaldehyde) that can be derived from lignocellulosic biomass. The use of syringaldehyde as a precursor to composites has the potential to reduce the cost and environmental impact of structural materials, while meeting or exceeding the performance of current petroleum derived resins.

Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably applanating at least a portion of a subject's ocular globe so as to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, as well as methods of assessing intracranial pressure that are based, at least in part, on the degree of papilledema, if any, present in the subject.

Abstract: A method to generate renewable high performance composites and thermoplastics. These materials can be generated from a renewable phenol (syringaldehyde) that can be derived from lignocellulosic biomass. The use of syringaldehyde as a precursor to composites has the potential to reduce the cost and environmental impact of structural materials, while meeting or exceeding the performance of current petroleum derived resins.

Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably applanating at least a portion of a subject's ocular globe so as to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, as well as methods of assessing intracranial pressure that are based, at least in part, on the degree of papilledema, if any, present in the subject.

Abstract: A new class of polymers based upon the radialene group as the parent repeating group and characterized by the following general formula: where R1, R2, R3, R4 are each independently any pi electron conjugated group, but not limited to: pyrrole, thiophene, benzene, naphthalene, furan, ethene, aniline, and n is an integer from 2 to 20,000. Furthermore, the individual R groups can be further functionalized with an alky group having 1 to 22 carbons; alkoxy group having 1 to 22 carbons; alkyl sulfonate having 1 to 22 carbons; alkyl phosphate group containing 1 to 22 carbons, alkoxy phosphate group having 1 to 22 carbons; ethenylendioxy group; propylene dioxy group.

Abstract: A method to generate renewable high performance composites and thermoplastics. These materials can be generated from a renewable phenol (syringaldehyde) that can be derived from lignocellulosic biomass. The use of syringaldehyde as a precursor to composites has the potential to reduce the cost and environmental impact of structural materials, while meeting or exceeding the performance of current petroleum derived resins.

Abstract: A method to generate renewable high performance composites and thermoplastics. These materials can be generated from a renewable phenol (syringaldehyde) that can be derived from lignocellulosic biomass. The use of syringaldehyde as a precursor to composites has the potential to reduce the cost and environmental impact of structural materials, while meeting or exceeding the performance of current petroleum derived resins.