Abstract: The present invention relates to stable, aqueous antibody formulations. In some embodiments, the stable, aqueous formulations comprise about 2 mg/mL to about 100 mg/mL of an anti-IL5R antibody, and about 0.002% to about 0.01% polysorbate-20. Also provided are methods of making and methods of using such antibody formulations.

Abstract: The present invention relates to stable. aqucous antibody formulations. In some embodiments, the stable, aqueous formulations comprise about 2 mg/mL to about 100 mg/mL of an anti-IL5R antibody, and about 0.002% to about 0.01% polysorbate-20. Also provided are methods of making and methods of using such antibody formulations.

Abstract: An apparatus including an interface and a processor. The interface may be configured to receive area data and sensor data from a plurality of vehicle sensors. The processor may be configured to extract road characteristics for a location from the area data, predict expected sensor readings at the location for the plurality of sensors based on the road characteristics, calculate dynamic limits for the sensor data in response to the expected sensor readings and determine a plausibility of the sensor data received from the interface when the vehicle reaches the location. The sensor data may be plausible if the sensor data is within the dynamic limits. A confidence level of the sensor data may be adjusted in response to the plausibility of the sensor data.

Abstract: An apparatus including an interface and a processor. The interface may be configured to receive area data and sensor data from a plurality of vehicle sensors. The processor may be configured to extract road characteristics for a location from the area data, predict expected sensor readings at the location for the plurality of sensors based on the road characteristics, calculate dynamic limits for the sensor data in response to the expected sensor readings and determine a plausibility of the sensor data received from the interface when the vehicle reaches the location. The sensor data may be plausible if the sensor data is within the dynamic limits. A confidence level of the sensor data may be adjusted in response to the plausibility of the sensor data.

Abstract: In a projectile launch environment, a fuzing safety device independently generates its own voltage upon setback which then is then used to arm the projectile. The arming is done independently of any on board battery rise time, and setback scenarios are detected free of false impacts such as dropping or jostling. The fuzing safety device includes a piezoelectric sensor for detecting motion in the projectile.

Abstract: The present invention relates to stable, aqueous antibody formulations. In some embodiments, the stable, aqueous formulations comprise about 2 mg/mL to about 100 mg/mL of an anti-IL5R antibody, and about 0.002% to about 0.01% polysorbate-20. Also provided are methods of making and methods of using such antibody formulations.

Abstract: The present invention relates to stable, aqueous antibody formulations. In some embodiments, the stable, aqueous formulations comprise about 2 mg/mL to about 100 mg/mL of an anti-IL5R antibody, and about 0.002% to about 0.01% polysorbate-20. Also provided are methods of making and methods of using such antibody formulations.

Abstract: An electromagnetic fire control system that includes a conductive surface and a power source such that the power source supplies power so that the conductive surface generates an electric field, the electric field is manipulated and interacts with a fire such that the fire is controlled.

Abstract: The present invention relates to stable, aqueous antibody formulations. In some embodiments, the stable, aqueous formulations comprise about 2 mg/mL to about 100 mg/mL of an anti-IL5R antibody, and about 0.002% to about 0.01% polysorbate-20. Also provided are methods of making and methods of using such antibody formulations.

Abstract: The present invention provides formulations of proteins comprising a variant Fc region that improve the stability in part by reducing the propensisty of such molecules to rapidly aggregate. The invention provides both liquid and lyophilized formulations either of which can be utilized to generate a high protein concentration liquid suitable for administration to a subject. The invention further provides methods of utilizing the formulations of the present invention for therapeutic or prophylactic treatment of diseases and disorders or for diagnostic purposes.

Abstract: The present invention provides formulations of proteins comprising a variant Fc region that improve the stability in part by reducing the propensisty of such molecules to rapidly aggregate. The invention provides both liquid and lyophilized formulations either of which can be utilized to generate a high protein concentration liquid suitable for administration to a subject. The invention further provides methods of utilizing the formulations of the present invention for therapeutic or prophylactic treatment of diseases and disorders or for diagnostic purposes.

Abstract: Methods and systems for automated notification of exceptional states are described. A system may identify candidate exceptional state locations to inject program code and report reaching the exceptional state to a location. Such reporting may be to a local repository or remote receiver. A method may automate identifying exceptional state conditions and reporting attributes associated with the conditions.