Abstract: Techniques are described for providing a threat analysis platform capable of automating actions performed to analyze security-related threats affecting IT environments. Users or applications can submit objects (e.g., URLs, files, etc.) for analysis by the threat analysis platform. Once submitted, the threat analysis platform routes the objects to dedicated engines that can perform static and dynamic analysis processes to determine a likelihood that an object is associated with malicious activity such as phishing attacks, malware, or other types of security threats.

Abstract: The present invention relates to novel blood-brain barrier (BBB) penetrable substituted bicyclic derivatives that can selectively inhibit ROCK2 and/or Rho-kinase mediated phosphorylation of myosin light chain phosphates, compositions comprising the derivatives, methods for preparing the derivatives and/or compositions, and methods for using the derivatives and/or compositions.

Abstract: Disclosed herein are embodiments of a wound treatment apparatus with electronic components integrated within a wound dressing. In some embodiments, a wound dressing apparatus can comprise a wound dressing. The wound dressing can comprise an absorbent material, an electronics unit comprising a negative pressure source, the electronics unit integrated within the wound dressing and at least partially encapsulated by a flexible film. The electronics unit can include translucent or transparent components that allow light to travel through to reach adhesives or coatings on the electronic components that would otherwise be obscured.

Abstract: A device including a rod with a tip and a channel formed in the tip. The device further includes a containment member including a first end and a second end opposite the first end. The second end is coupled to the tip, and the containment member includes an opening positioned at the first end. An expansion string and a compression string are coupled to the opening of the containment member. The expansion string extends through the channel in the tip.

Abstract: In one embodiment, a depassivating circuit includes a battery, a resistive load coupled to the battery, and a magnetic field sensor. The magnetic field sensor detects a presence of a magnetic field. The magnetic field sensor depassivates the battery by causing current from the battery to flow through the resistive load, in response to the presence of the magnetic field. The magnetic field sensor detects removal of the magnetic field. The magnetic field sensor ends depassivation of the battery, in response to the removal of the magnetic field.

Abstract: Disclosed herein are embodiments of a wound treatment apparatus with electronic components integrated within a wound dressing. In some embodiments, a wound dressing apparatus can comprise a wound contact layer, an absorbent layer over the wound contact layer, the absorbent layer comprising one or more apertures, a cover layer configured to cover and form a seal over the wound contact layer and the absorbent layer, and an electronics assembly comprising a negative pressure source. A portion of the cover layer overlying the one or more apertures in the absorbent layer can be configured to be compressed within the aperture in the absorbent layer when negative pressure is applied to the wound dressing apparatus. The compressed cover layer can indicate a level of negative pressure below the cover layer. In some embodiments, the wound dressing apparatus can comprise an indicator material layer and a cover layer configured to cover and form a seal over the wound contact layer and the indicator material layer.

Abstract: Methods, systems, and apparatus for simulating a quantum system. In one aspect, a method includes performing a first quantized quantum algorithm on an initial quantum state to simulate time evolution of a fermionic system and generate a time evolved quantum state; and measuring, by the quantum computer, the time evolved quantum state to obtain one or more reduced density matrices in first quantization, the measuring including performing a classical shadows method that applies separate random Clifford channels to each qubit register of multiple qubit registers that represent respective occupied orbitals in the fermionic system.

Abstract: The present disclosure relates to an electronic smoking article that provides for improved aerosol delivery. Particularly, the article provides for separate delivery of two or more components of an aerosol precursor composition to one or more heaters so as to control the rate of delivery or the rate of heating of the separate components of the aerosol precursor composition.

Abstract: A method is disclosed for improving the solubility of a poorly soluble drug compound such as by mixing the poorly water-soluble drug compound (such as alprostadil, sildenafil, tadalafil, vardenafil, avanafil, or a pharmaceutically acceptable salt of any thereof) with a non-nutritive sugar such as rubusoside, rebaudioside A, dulcoside B, dodecyl-?-D-maltoside (DDM), or stevioside, or any combination thereof in the presence of a pharmaceutically acceptable solvent such as ethanol and then removing the solvent to creating a water-soluble drug-sugar complex.

Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.

Abstract: Embodiments of a negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a pump assembly, canister, and a wound dressing configured to be positioned over a wound. The pump assembly, canister, and the wound dressing can be fluidically connected to facilitate delivery of negative pressure to a wound. The pump assembly can present graphical user interface screens for controlling and monitoring delivery of negative pressure. The system can be configured to efficiently deliver negative pressure and to detect and indicate presence of certain conditions, such as low pressure, high pressure, leak, canister full, and the like. Monitoring and detection of operating condition can be performed by measuring one or more operational parameters, such as pressure, flow rate, and the like.

Abstract: Techniques are described for providing a threat analysis platform capable of automating actions performed to analyze security-related threats affecting IT environments. Users or applications can submit objects (e.g., URLs, files, etc.) for analysis by the threat analysis platform. Once submitted, the threat analysis platform routes the objects to dedicated engines that can perform static and dynamic analysis processes to determine a likelihood that an object is associated with malicious activity such as phishing attacks, malware, or other types of security threats.

Abstract: A platform for monitoring range of motion in a joint includes initiating a range of motion monitoring application and connecting the application to a video communication platform. Video data, comprising the joint of the patient, is received from the communication platform. The platform may be used to determine that the patient is in position for calculating a range of motion of the joint, and capture an image of the joint from the received video data. The platform receives, from a user, a selection of a first set of points used in measuring range of motion, and calculates a first angle measurement associated with the range of motion of the joint based on the selected set of points. The captured image is displayed together with an overlay comprising the first set of points and the first calculated angle, and the captured image and the overlay are stored to a storage device.

Abstract: A densitometer assembly comprises a pipe fabricated from a high-yield steel, a radioactive source, and a detector. The radioactive source is mounted on an exterior wall of the pipe and is adapted to emit gamma radiation in a defined beam. The detector is mounted on an opposing, facing exterior wall of the pipe in alignment with the gamma radiation beam and is adapted to detect gamma radiation.

Abstract: Techniques are described for providing a threat analysis platform capable of automating actions performed to analyze security-related threats affecting IT environments. Users or applications can submit objects (e.g., URLs, files, etc.) for analysis by the threat analysis platform. Once submitted, the threat analysis platform routes the objects to dedicated engines that can perform static and dynamic analysis processes to determine a likelihood that an object is associated with malicious activity such as phishing attacks, malware, or other types of security threats.

Abstract: Various embodiments disclosed relate to a method of quality control for a biological sample. The method can include receiving genetic data sequenced from the biological sample, determining whether an endogenous control is apparent in the genetic data, and in the event that the endogenous control is apparent in the genetic data, determining whether the biological sample is contaminated. The genetic data can be analyzed for sequences from both pathogen genetic material and mitochondrial genetic material. The endogenous control can be determined based on whether at least a threshold amount of the genetic data includes sequences for the mitochondrial genetic material.

Abstract: A determination is made whether a requested transaction of a certain type or class is available (i.e., suitable for execution or queueing) within a processing environment. In the case that a transaction of the certain type or class is not available, the request to be rejected is enabled, thus avoiding queuing of the requested transaction. Embodiments may thus provide a mechanism to protect a processing environment by avoiding the overhead of creating and removing specific transactions of the certain type or class.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. A wound dressing apparatus can comprises a wound contact layer, at least one absorbent layer, an electronics unit comprising a negative pressure source unit, and a cover layer. The electronics unit can comprise a plurality of sensors positioned on a printed circuit board and an inlet protection mechanism of the negative pressure source unit comprises a first recess in fluid communication with a first sensor and the outlet or exhaust mechanism negative pressure source unit comprises a second recess in fluid communication with a second sensor.

Abstract: A method of acid mist suppression in copper electrowinning is described. In various embodiments, at least one liquid licorice root extract, powdered licorice root extract, or reconstituted licorice extract is added in an amount sufficient to the acidic electrolyte solution of the copper electrowinning process to suppress acid mist from the acidic electrolyte solution during the copper electrowinning process. In various embodiments, combinations of licorice extract and surfactant show synergies in acid mist suppression during copper electrowinning.

Abstract: Implementations provide methods including actions of processing patient data to generate one or more graphical representations of the patient data, at least one graphical representation of the one or more graphical representations including a waveform, displaying at least one waveform segment of the waveform, and displaying calipers associated with the at least one waveform segment, each caliper being associated with an interval, where displaying the calipers includes, for each caliper: receiving a measurement value of the interval associated with the caliper, determining respective positions of a first handle and a second handle of the caliper based on the measurement, and displaying the first handle and the second handle in the respective positions relative to the at least one waveform segment.