Patents by Inventor William M. Acree

William M. Acree has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030170251
    Abstract: This invention provides a feline vaccine composition comprising an immunogenically active component having inactivated mammalian chlamydial cells or antigens derived therefrom, in combination with an effective amount of an immunogencally suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent chlamydia, e.g. C. psittaci, infections or diseases in felines, and may also be combined with other vaccine compositions or therapy. A process for producing C. psittaci suitable for use in the production of safe and effective chlamydia vaccines, and a method for preventing chlamydia infections or diseases in felines, are also provided.
    Type: Application
    Filed: February 10, 2003
    Publication date: September 11, 2003
    Applicant: American Home Products Corporation
    Inventors: Hsien-Jue Chu, Lloyd Chavez, William M. Acree, Lucille W.S. Chang
  • Patent number: 6004563
    Abstract: This invention provides a feline vaccine composition comprising an immunogenically active component having inactivated mammalian chlamydial cells or antigens derived there-from, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent chlamydia, e.g. C. psittaci, infections or diseases in felines, and may also be combined with other vaccine compositions or therapy. A process for producing C. psittaci suitable for use in the production of safe and effective chlamydia vaccines, and a method for preventing chlamydia infections or diseases in felines, are also provided.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 21, 1999
    Assignee: American Home Products Corporation
    Inventors: Hsien-Jue Chu, Lloyd Chavez, William M. Acree, Lucille W. S. Chang
  • Patent number: 5811104
    Abstract: The present invention relates to the development of an efficacious vaccine against Feline Infectious Peritonitis Virus (FIPV). The invention provides the tools for the synthesis and manipulation of the structural and non-structural proteins of FIPV. These proteins are able to elicit an immune response in cats against FIPV. The recombinant virus vectors which express the E1 or N proteins of the virus or the recombinant produced viral proteins themselves are able to elicit an immune response.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: September 22, 1998
    Assignees: American Home Products Corporation, Scios, Inc.
    Inventors: Beverly Dale, Miles Yamanaka, William M. Acree, Lloyd G. Chavez, Jr.
  • Patent number: 5780266
    Abstract: The present invention provides tools which are useful for the diagnosis of an animal's exposure to feline infectious peritonitis virus (FIPV) or susceptibility to FIPV. The diagnostic tools are composed of nucleic acid sequences which encode structural and nonstructural FIPV proteins and antibodies generated against FIPV proteins. The FIPV proteins may also be useful as subunit vaccines.
    Type: Grant
    Filed: March 30, 1994
    Date of Patent: July 14, 1998
    Assignees: Scios Inc., American Home Products Corporation
    Inventors: Beverly Dale, Miles Yamanaka, William M. Acree, Lloyd G. Chavez, Jr.
  • Patent number: 5679353
    Abstract: A bovine vaccine composition comprising an immunogenically active component having inactivated bovine Trichomonas cells or antigens derived therefrom, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or dilent. The vaccine composition is useful to prevent Tritrichomonas (Trichomonas), e.g., T. foetus, infection in bovine, and may also be combined with other vaccine compositions or therapy. A method for preventing Trichomonas infection in bovine is also provided.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 21, 1997
    Assignee: American Home Products Corporation
    Inventors: Mark Hall, Bonnie Wallace, William M. Acree, Lloyd G. Chavez
  • Patent number: 5242686
    Abstract: This invention provides a feline vaccine composition comprising an immunogenically active component having inactivated mammalian chlamydial cells or antigens derived therefrom, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent chlamydia, e.g. C. psittaci, infections or diseases in felines, and may also be combined with other vaccine compositions or therapy. A process for producing C. psittaci suitable for use in the production of safe and effective chlamydia vaccines, and a method for preventing chlamydia infections or diseases in felines, are also provided.
    Type: Grant
    Filed: November 7, 1990
    Date of Patent: September 7, 1993
    Assignee: American Home Products Corporation
    Inventors: Hsien-Jue Chu, Lloyd Chavez, William M. Acree, Lucille W. S. Chang
  • Patent number: 5223253
    Abstract: This invention provides a bovine vaccine composition comprising an immunogenically active component having inactivated bovine Trichomonas cells or antigens derived therefrom, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent Tritrichomonas (Trichomonas), e.g., T. foetusinfection in bovine, and may also be combined with other vaccine compositions or therapy. A method for preventing Trichomonas infection in bovine is also provided.
    Type: Grant
    Filed: September 28, 1989
    Date of Patent: June 29, 1993
    Assignee: American Home Products Corporation
    Inventors: Mark Hall, Bonnie Wallace, William M. Acree, Lloyd G. Chavez
  • Patent number: 5047238
    Abstract: An efficacious parenterally administered inactivated canine coronavirus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent canine coronavirus is produced. A method for propagation of the canine coronavirus and its attenuation and a method of evaluating the effectiveness of a canine coronavirus vaccine in canines is also disclosed.
    Type: Grant
    Filed: March 24, 1988
    Date of Patent: September 10, 1991
    Assignee: American Home Products Corporation
    Inventors: William M. Acree, Bobby Edwards, John W. Black
  • Patent number: 5013663
    Abstract: An efficacious parenterally administered modified live Canine Corona virus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent Canine Corona virus is produced. A method for propagation of the Canine Corona virus and its attenuation and a method of evaluating the effectiveness of a Canine Corona virus vaccine in canines is also disclosed.
    Type: Grant
    Filed: March 24, 1989
    Date of Patent: May 7, 1991
    Assignee: American Home Products Corporation
    Inventors: William M. Acree, John W. Black
  • Patent number: 4824785
    Abstract: An efficacious parenterally administered modified live Canine Corona virus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent Canine Corona virus is produced. A method for propagation of the Canine Corona virus and its attenuation and a method of evaluating the effectiveness of a Canine Corona virus vaccine in canines is also disclosed.
    Type: Grant
    Filed: January 22, 1986
    Date of Patent: April 25, 1989
    Assignee: American Home Products Corp. (Del)
    Inventors: William M. Acree, Bobby Edwards, John W. Black
  • Patent number: 4567042
    Abstract: An efficacious parenterally administered inactivated canine coronavirus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent canine coronavirus is produced. A method for propagation of the canine coronavirus and its attenuation and a method of evaluating the effectiveness of a canine coronavirus vaccine in canines is also disclosed.
    Type: Grant
    Filed: June 7, 1984
    Date of Patent: January 28, 1986
    Assignee: American Home Products Corporation
    Inventors: William M. Acree, Bobby Edwards, John W. Black
  • Patent number: 4567043
    Abstract: An efficacious parenterally administered modified live Canine Corona virus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent Canine Corona virus is produced. A method for propagation of the Canine Corona virus and its attenuation and a method of evaluating the effectiveness of a Canine Corona virus vaccine in canines is also disclosed.
    Type: Grant
    Filed: June 15, 1983
    Date of Patent: January 28, 1986
    Assignee: American Home Products Corporation (Del.)
    Inventors: William M. Acree, Bobby Edwards, John W. Black