Patents by Inventor William M. Acree
William M. Acree has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20030170251Abstract: This invention provides a feline vaccine composition comprising an immunogenically active component having inactivated mammalian chlamydial cells or antigens derived therefrom, in combination with an effective amount of an immunogencally suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent chlamydia, e.g. C. psittaci, infections or diseases in felines, and may also be combined with other vaccine compositions or therapy. A process for producing C. psittaci suitable for use in the production of safe and effective chlamydia vaccines, and a method for preventing chlamydia infections or diseases in felines, are also provided.Type: ApplicationFiled: February 10, 2003Publication date: September 11, 2003Applicant: American Home Products CorporationInventors: Hsien-Jue Chu, Lloyd Chavez, William M. Acree, Lucille W.S. Chang
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Patent number: 6004563Abstract: This invention provides a feline vaccine composition comprising an immunogenically active component having inactivated mammalian chlamydial cells or antigens derived there-from, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent chlamydia, e.g. C. psittaci, infections or diseases in felines, and may also be combined with other vaccine compositions or therapy. A process for producing C. psittaci suitable for use in the production of safe and effective chlamydia vaccines, and a method for preventing chlamydia infections or diseases in felines, are also provided.Type: GrantFiled: June 6, 1995Date of Patent: December 21, 1999Assignee: American Home Products CorporationInventors: Hsien-Jue Chu, Lloyd Chavez, William M. Acree, Lucille W. S. Chang
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Patent number: 5811104Abstract: The present invention relates to the development of an efficacious vaccine against Feline Infectious Peritonitis Virus (FIPV). The invention provides the tools for the synthesis and manipulation of the structural and non-structural proteins of FIPV. These proteins are able to elicit an immune response in cats against FIPV. The recombinant virus vectors which express the E1 or N proteins of the virus or the recombinant produced viral proteins themselves are able to elicit an immune response.Type: GrantFiled: May 9, 1995Date of Patent: September 22, 1998Assignees: American Home Products Corporation, Scios, Inc.Inventors: Beverly Dale, Miles Yamanaka, William M. Acree, Lloyd G. Chavez, Jr.
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Patent number: 5780266Abstract: The present invention provides tools which are useful for the diagnosis of an animal's exposure to feline infectious peritonitis virus (FIPV) or susceptibility to FIPV. The diagnostic tools are composed of nucleic acid sequences which encode structural and nonstructural FIPV proteins and antibodies generated against FIPV proteins. The FIPV proteins may also be useful as subunit vaccines.Type: GrantFiled: March 30, 1994Date of Patent: July 14, 1998Assignees: Scios Inc., American Home Products CorporationInventors: Beverly Dale, Miles Yamanaka, William M. Acree, Lloyd G. Chavez, Jr.
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Patent number: 5679353Abstract: A bovine vaccine composition comprising an immunogenically active component having inactivated bovine Trichomonas cells or antigens derived therefrom, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or dilent. The vaccine composition is useful to prevent Tritrichomonas (Trichomonas), e.g., T. foetus, infection in bovine, and may also be combined with other vaccine compositions or therapy. A method for preventing Trichomonas infection in bovine is also provided.Type: GrantFiled: June 6, 1995Date of Patent: October 21, 1997Assignee: American Home Products CorporationInventors: Mark Hall, Bonnie Wallace, William M. Acree, Lloyd G. Chavez
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Patent number: 5242686Abstract: This invention provides a feline vaccine composition comprising an immunogenically active component having inactivated mammalian chlamydial cells or antigens derived therefrom, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent chlamydia, e.g. C. psittaci, infections or diseases in felines, and may also be combined with other vaccine compositions or therapy. A process for producing C. psittaci suitable for use in the production of safe and effective chlamydia vaccines, and a method for preventing chlamydia infections or diseases in felines, are also provided.Type: GrantFiled: November 7, 1990Date of Patent: September 7, 1993Assignee: American Home Products CorporationInventors: Hsien-Jue Chu, Lloyd Chavez, William M. Acree, Lucille W. S. Chang
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Patent number: 5223253Abstract: This invention provides a bovine vaccine composition comprising an immunogenically active component having inactivated bovine Trichomonas cells or antigens derived therefrom, in combination with an effective amount of an immunogenically suitable adjuvant; and a veterinary pharmaceutically acceptable carrier or diluent. The vaccine composition is useful to prevent Tritrichomonas (Trichomonas), e.g., T. foetusinfection in bovine, and may also be combined with other vaccine compositions or therapy. A method for preventing Trichomonas infection in bovine is also provided.Type: GrantFiled: September 28, 1989Date of Patent: June 29, 1993Assignee: American Home Products CorporationInventors: Mark Hall, Bonnie Wallace, William M. Acree, Lloyd G. Chavez
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Patent number: 5047238Abstract: An efficacious parenterally administered inactivated canine coronavirus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent canine coronavirus is produced. A method for propagation of the canine coronavirus and its attenuation and a method of evaluating the effectiveness of a canine coronavirus vaccine in canines is also disclosed.Type: GrantFiled: March 24, 1988Date of Patent: September 10, 1991Assignee: American Home Products CorporationInventors: William M. Acree, Bobby Edwards, John W. Black
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Patent number: 5013663Abstract: An efficacious parenterally administered modified live Canine Corona virus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent Canine Corona virus is produced. A method for propagation of the Canine Corona virus and its attenuation and a method of evaluating the effectiveness of a Canine Corona virus vaccine in canines is also disclosed.Type: GrantFiled: March 24, 1989Date of Patent: May 7, 1991Assignee: American Home Products CorporationInventors: William M. Acree, John W. Black
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Patent number: 4824785Abstract: An efficacious parenterally administered modified live Canine Corona virus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent Canine Corona virus is produced. A method for propagation of the Canine Corona virus and its attenuation and a method of evaluating the effectiveness of a Canine Corona virus vaccine in canines is also disclosed.Type: GrantFiled: January 22, 1986Date of Patent: April 25, 1989Assignee: American Home Products Corp. (Del)Inventors: William M. Acree, Bobby Edwards, John W. Black
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Patent number: 4567042Abstract: An efficacious parenterally administered inactivated canine coronavirus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent canine coronavirus is produced. A method for propagation of the canine coronavirus and its attenuation and a method of evaluating the effectiveness of a canine coronavirus vaccine in canines is also disclosed.Type: GrantFiled: June 7, 1984Date of Patent: January 28, 1986Assignee: American Home Products CorporationInventors: William M. Acree, Bobby Edwards, John W. Black
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Patent number: 4567043Abstract: An efficacious parenterally administered modified live Canine Corona virus vaccine which provides systemic, humoral protection and also protection of the intestinal tract in dogs from infection by virulent Canine Corona virus is produced. A method for propagation of the Canine Corona virus and its attenuation and a method of evaluating the effectiveness of a Canine Corona virus vaccine in canines is also disclosed.Type: GrantFiled: June 15, 1983Date of Patent: January 28, 1986Assignee: American Home Products Corporation (Del.)Inventors: William M. Acree, Bobby Edwards, John W. Black