Patents by Inventor William M. Appling
William M. Appling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240050636Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.Type: ApplicationFiled: October 24, 2023Publication date: February 15, 2024Applicant: Delcath Systems, Inc.Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
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Patent number: 11833286Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.Type: GrantFiled: July 7, 2021Date of Patent: December 5, 2023Assignee: Delcath Systems, Inc.Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
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Publication number: 20230211063Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: March 10, 2023Publication date: July 6, 2023Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 11633528Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: December 21, 2021Date of Patent: April 25, 2023Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20220111132Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: December 21, 2021Publication date: April 14, 2022Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 11241522Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: January 10, 2020Date of Patent: February 8, 2022Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20210330875Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.Type: ApplicationFiled: July 7, 2021Publication date: October 28, 2021Applicant: Delcath Systems, Inc.Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
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Patent number: 11083831Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.Type: GrantFiled: December 22, 2018Date of Patent: August 10, 2021Assignee: Delcath Systems, Inc.Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
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Publication number: 20200147288Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: January 10, 2020Publication date: May 14, 2020Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10569004Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: June 12, 2019Date of Patent: February 25, 2020Assignee: DELCATH SYSTEMS, INC.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20190328443Abstract: An energy delivery probe and method of using the energy delivery probe to treat a patient is provided herein. The energy delivery probe has at least one probe body having a longitudinal axis and at least a first trocar and a second trocar. At least a portion of each trocar is disposed with the at least one probe body. The distance between the first trocar and the second trocar is adjustable between a first position and a second position. Each of the deployed electrodes has an energy delivery surface of a sufficient size to create a volumetric ablation zone between the deployed electrodes. The energy delivery probe is connected to an energy source. At least one cable couples the energy delivery probe to the energy source.Type: ApplicationFiled: June 19, 2019Publication date: October 31, 2019Applicant: AngioDynamics, Inc.Inventors: Moss Kevin, William M. Appling
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Publication number: 20190314606Abstract: A medical device system is provided herein which has an elongated, flexible hollow member with an expandable infusion segment attached at the most distal end of the device. The device has a plurality of fluid infusion ports on the expandable infusion segment for delivering an intended fluid to a target site in a body lumen. Additionally, a method is provided herein for infusing an intended fluid to a target site within a body lumen.Type: ApplicationFiled: June 27, 2019Publication date: October 17, 2019Applicant: AngioDynamics, Inc.Inventors: Giorgio di Palma, William A. Cartier, William M. Appling
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Publication number: 20190290823Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: June 12, 2019Publication date: September 26, 2019Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10369264Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: September 10, 2018Date of Patent: August 6, 2019Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10350386Abstract: A medical device system is provided herein which has an elongated, flexible hollow member with an expandable infusion segment attached at the most distal end of the device. The device has a plurality of fluid infusion ports on the expandable infusion segment for delivering an intended fluid to a target site in a body lumen. Additionally, a method is provided herein for infusing an intended fluid to a target site within a body lumen.Type: GrantFiled: October 12, 2015Date of Patent: July 16, 2019Assignee: AngioDynamics, Inc.Inventors: Giorgio di Palma, William A Cartier, William M Appling
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Publication number: 20190117872Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.Type: ApplicationFiled: December 22, 2018Publication date: April 25, 2019Applicant: Delcath Systems, Inc.Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
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Patent number: 10238453Abstract: An endovascular laser treatment device for causing closure of a blood vessel uses an optical fiber adapted to be inserted into a blood vessel. An inner sleeve is arranged around a distal portion of the optical fiber core such that both distal ends of the inner sleeve and the optical fiber core form an enlarged light emitting face. The enlarged emitting face provides substantially lower power density while providing the same amount of total energy during a treatment session. An outer sleeve arranged around the inner sleeve acts as a spacer to position the light emitting face away from an inner wall of the blood vessel. The enlarged light emitting face and the outer sleeve acting as a spacer reduces the possibility of thermal run-away and device damage, and reduce the possibility of vessel perforations, leading to less bruising, post-operative pain and other clinical complications.Type: GrantFiled: October 15, 2015Date of Patent: March 26, 2019Assignee: AngioDynamics, Inc.Inventors: William M. Appling, Ralph A. Meyer, Theodore J. Beyer, William C. Hamilton, Jr., Joe D. Brown
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Patent number: 10195334Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.Type: GrantFiled: March 16, 2016Date of Patent: February 5, 2019Assignee: Delcath Systems, Inc.Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
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Publication number: 20190001044Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: September 10, 2018Publication date: January 3, 2019Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10098997Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: July 17, 2017Date of Patent: October 16, 2018Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton