Patents by Inventor William M. Appling

William M. Appling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240050636
    Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.
    Type: Application
    Filed: October 24, 2023
    Publication date: February 15, 2024
    Applicant: Delcath Systems, Inc.
    Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
  • Patent number: 11833286
    Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: December 5, 2023
    Assignee: Delcath Systems, Inc.
    Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
  • Publication number: 20230211063
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: March 10, 2023
    Publication date: July 6, 2023
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 11633528
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: December 21, 2021
    Date of Patent: April 25, 2023
    Assignee: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Publication number: 20220111132
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 14, 2022
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 11241522
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: February 8, 2022
    Assignee: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Publication number: 20210330875
    Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.
    Type: Application
    Filed: July 7, 2021
    Publication date: October 28, 2021
    Applicant: Delcath Systems, Inc.
    Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
  • Patent number: 11083831
    Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.
    Type: Grant
    Filed: December 22, 2018
    Date of Patent: August 10, 2021
    Assignee: Delcath Systems, Inc.
    Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
  • Publication number: 20200147288
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: January 10, 2020
    Publication date: May 14, 2020
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 10569004
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: February 25, 2020
    Assignee: DELCATH SYSTEMS, INC.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Publication number: 20190328443
    Abstract: An energy delivery probe and method of using the energy delivery probe to treat a patient is provided herein. The energy delivery probe has at least one probe body having a longitudinal axis and at least a first trocar and a second trocar. At least a portion of each trocar is disposed with the at least one probe body. The distance between the first trocar and the second trocar is adjustable between a first position and a second position. Each of the deployed electrodes has an energy delivery surface of a sufficient size to create a volumetric ablation zone between the deployed electrodes. The energy delivery probe is connected to an energy source. At least one cable couples the energy delivery probe to the energy source.
    Type: Application
    Filed: June 19, 2019
    Publication date: October 31, 2019
    Applicant: AngioDynamics, Inc.
    Inventors: Moss Kevin, William M. Appling
  • Publication number: 20190314606
    Abstract: A medical device system is provided herein which has an elongated, flexible hollow member with an expandable infusion segment attached at the most distal end of the device. The device has a plurality of fluid infusion ports on the expandable infusion segment for delivering an intended fluid to a target site in a body lumen. Additionally, a method is provided herein for infusing an intended fluid to a target site within a body lumen.
    Type: Application
    Filed: June 27, 2019
    Publication date: October 17, 2019
    Applicant: AngioDynamics, Inc.
    Inventors: Giorgio di Palma, William A. Cartier, William M. Appling
  • Publication number: 20190290823
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: June 12, 2019
    Publication date: September 26, 2019
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 10369264
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: August 6, 2019
    Assignee: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 10350386
    Abstract: A medical device system is provided herein which has an elongated, flexible hollow member with an expandable infusion segment attached at the most distal end of the device. The device has a plurality of fluid infusion ports on the expandable infusion segment for delivering an intended fluid to a target site in a body lumen. Additionally, a method is provided herein for infusing an intended fluid to a target site within a body lumen.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: July 16, 2019
    Assignee: AngioDynamics, Inc.
    Inventors: Giorgio di Palma, William A Cartier, William M Appling
  • Publication number: 20190117872
    Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.
    Type: Application
    Filed: December 22, 2018
    Publication date: April 25, 2019
    Applicant: Delcath Systems, Inc.
    Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
  • Patent number: 10238453
    Abstract: An endovascular laser treatment device for causing closure of a blood vessel uses an optical fiber adapted to be inserted into a blood vessel. An inner sleeve is arranged around a distal portion of the optical fiber core such that both distal ends of the inner sleeve and the optical fiber core form an enlarged light emitting face. The enlarged emitting face provides substantially lower power density while providing the same amount of total energy during a treatment session. An outer sleeve arranged around the inner sleeve acts as a spacer to position the light emitting face away from an inner wall of the blood vessel. The enlarged light emitting face and the outer sleeve acting as a spacer reduces the possibility of thermal run-away and device damage, and reduce the possibility of vessel perforations, leading to less bruising, post-operative pain and other clinical complications.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: March 26, 2019
    Assignee: AngioDynamics, Inc.
    Inventors: William M. Appling, Ralph A. Meyer, Theodore J. Beyer, William C. Hamilton, Jr., Joe D. Brown
  • Patent number: 10195334
    Abstract: Provided is a filter apparatus, comprising two or more filter cartridges having a first end with an inlet and screen and a second end with an outlet and screen, and walls to contain a filter media held in a housing for holding the two or more filter cartridges in about the same orientation, and an attachment clamp connected to the housing. Also provided is a housing for holding two or more filter cartridges in about the same orientation and a method of using the filter apparatus and housing.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: February 5, 2019
    Assignee: Delcath Systems, Inc.
    Inventors: William M. Appling, Stephen N. Engelhard, Matthew G. Barton
  • Publication number: 20190001044
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: September 10, 2018
    Publication date: January 3, 2019
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 10098997
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: October 16, 2018
    Assignee: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton