Patents by Inventor William M. Bennett

William M. Bennett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition having reduced nephrotoxocity comprising a fatty acid containing component and cyclosporine
    Patent number: 5118493
    Abstract: Compositions comprising cyclosporine in combination with a vehicle comprising a fatty acid component comprising a fatty acid of the omega-3 or a pharmacologically acceptable salt thereof. Methods for mediating the nephrotoxic effect of cyclosporine and for reducing cyclosporine induced renal prostaglandins comprising administering said cyclosporine in combination with said fatty acid component or a pharmacologically acceptable salt thereof. Eicosapentaenoic acid and docosahexanoic acid are preferred omega-3 fatty acids of the present invention. The compositions and methods of the present invention are useful in clinical and preclinical therapeutic cyclosporine treatment of animals, including humans.
    Type: Grant
    Filed: January 11, 1991
    Date of Patent: June 2, 1992
    Assignees: Brigham and Women's Hospital, Oregon Health Sciences University
    Inventors: Vicki E. Kelley, William M. Bennett