Patents by Inventor William M. Maiese

William M. Maiese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plasmids derived from actinomadura species
    Patent number: 4983525
    Abstract: Plasmid DNA was isolated from two Actinomadura species and characterized by mapping the sites of restriction endonuclease cleavages and by calculation of total molecular size.
    Type: Grant
    Filed: July 2, 1987
    Date of Patent: January 8, 1991
    Assignee: American Cyanamid Company
    Inventors: Jerald S. Feitelson, William M. Maiese
  • Method for controlling chronic respiratory disease, fowl cholera and necrotic enteritis in avian species
    Patent number: 4968493
    Abstract: This invention provides a method for treating chronic respiratory disease, fowl cholera and necrotic enteritis in infected birds, by orally administering thereto a pharmaceutically effective amount of antibiotic LL-E19020.alpha., antibiotic LL-E19020.beta. or a physiologically acceptable salt thereof.
    Type: Grant
    Filed: June 19, 1989
    Date of Patent: November 6, 1990
    Assignee: American Cyanamid Company
    Inventors: Guy T. Carter, Michael Greenstein, Joseph J. Goodman, Donald B. Borders, William M. Maiese, Raymond T. Testa
  • Antibiotic LL-C19004
    Patent number: 4870019
    Abstract: A new antibacterial agent designated LL-C19004 is described, which antibacterial agent is produced through microbiological fermentation, under controlled conditions using a new species of Saccharothrix, Saccharothrix espanaensis (NRRL 15764).
    Type: Grant
    Filed: November 21, 1986
    Date of Patent: September 26, 1989
    Assignee: American Cyanamid Company
    Inventors: Jane P. Kirby, Donald B. Borders, May D. Lee, William M. Maiese, Raymond T. Testa, David P. Labeda
  • Culture and process for producing antibiotic LL-D42067alpha
    Patent number: 4774184
    Abstract: The invention is a process for the production by fermentation of the antibacterial and antiparasitic agents designated LL-D42067.alpha., to methods for its recovery and concentration from crude solutions and to processes for its purification. The invention includes within its scope the biologically pure culture of the antibiotic.
    Type: Grant
    Filed: August 14, 1985
    Date of Patent: September 27, 1988
    Assignee: American Cyanamid Company
    Inventors: Taikwang M. Lee, Donald B. Borders, Joseph J. Goodman, Raymond T. Testa, William M. Maiese, David P. Labeda
  • Antibiotic LL-E19020 .alpha. and .beta.
    Patent number: 4705688
    Abstract: This invention relates to antibiotic LL-E19020.alpha. and LL-E19020.beta. derived from the microorganism Streptomyces lydicus subspecies tanzanius NRRL 18036, which are useful as an antibacterial agent.
    Type: Grant
    Filed: June 30, 1986
    Date of Patent: November 10, 1987
    Assignee: American Cyanamid Company
    Inventors: Guy T. Carter, Michael Greenstein, Joseph J. Goodman, Donald B. Borders, William M. Maiese, Raymond T. Testa
  • Antibiotic LL-C19004
    Patent number: 4699790
    Abstract: A new antibacterial agent designated LL-C19004 is described, which antibacterial agent is produced through microbiological fermentation, under controlled conditions using a new species of Saccharothrix, Saccharothrix espanaensis (NRRL 15764).
    Type: Grant
    Filed: September 13, 1985
    Date of Patent: October 13, 1987
    Assignee: American Cyanamid Company
    Inventors: Jane P. Kirby, Donald B. Borders, May D. Lee, William M. Maiese, Raymond T. Testa, David P. Labeda
  • Antitumor agents LL-D49194.alpha..sub.1, LL-D49194.beta..sub.1, LL-D49194.beta..sub.2, LL-D49194.beta..sub.3, LL-D49194.gamma., LL-D49194.delta., LL-D49194.epsilon., LL-D49194.xi., LL-D49194.eta., LL-D49194.omega..sub.1, LL-D49194.omega..sub.2, and LL-D49194.omega..sub.3
    Patent number: 4626503
    Abstract: Antitumor agents LL-D49194.alpha..sub.1, LL-D49194.beta..sub.1, LL-D49194.beta..sub.2, LL-D49194.beta..sub.3, LL-D49194.gamma., LL-D49194.delta., LL-D49194.epsilon., LL-D49194.xi., LL-D49194.eta., LL-D49194.omega., LL-D49194.omega..sub.2 and LL-D49194.omega..sub.3.
    Type: Grant
    Filed: February 14, 1985
    Date of Patent: December 2, 1986
    Assignee: American Cyanamid Company
    Inventors: May D. Lee, Amedeo A. Fantini, David P. Labeda, William M. Maiese, Raymond T. Testa, Donald B. Borders
  • Antibiotic LL-D42067.alpha.
    Patent number: 4551533
    Abstract: Antibiotic LL-D42067.alpha. derived by aerobic fermentation of the microorganism Actinomadura madurae subspecies simaoensis NRRL 15734, useful as an antibacterial and antiparasitic agent.
    Type: Grant
    Filed: March 26, 1984
    Date of Patent: November 5, 1985
    Assignee: American Cyanamid Company
    Inventors: Taikwang M. Lee, Donald B. Borders, Joseph J. Goodman, Raymond T. Testa, William M. Maiese, David P. Labeda
  • Production of antibiotic FR-02A (efrotomycin) by streptomyces lactamdurans
    Patent number: 4065356
    Abstract: An antibiotic, designated FR-02A or efrotomycin, is obtained by culturing Streptomyces lactamdurans in a fermentation broth and extracting the whole broth with a water immiscible polar organic solvent to obtain the antibiotic FR-02A.
    Type: Grant
    Filed: March 1, 1977
    Date of Patent: December 27, 1977
    Assignee: Merck & Co., Inc.
    Inventors: William M. Maiese, Richard G. Wax
  • Antibiotic FR-02A and therapeutic compositions thereof
    Patent number: 4024251
    Abstract: This invention relates to a new antibiotic agent which also possesses growth promoting activity. The antibiotic is isolated from the fermentation broth of Streptomyces lactamdurans by solvent extraction and designated Efrotomycin.
    Type: Grant
    Filed: February 12, 1976
    Date of Patent: May 17, 1977
    Assignee: Merck & Co., Inc.
    Inventors: William M. Maiese, Richard G. Wax